Friday, 20 Apr 2018

RA/Inflammatory arthritis

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01 Apr 2018 Social RT @RajkiranDudam: #Vasculitis @alfredmahr https://t.co/dLQfqRYtmr
29 Mar 2018 News Precision Genetics Can Predict Methotrexate Non-Responders
29 Mar 2018 Social Epigenetic architecture changes represented by a chromosome conformation signatures (IFNAR1, IL-21R, IL-23, CXCL13, IL-17A) can accurately PREDICT MTX Nonresponse in 90% of early RA pts (N=59) . https://t.co/FQPwcOffsT
27 Mar 2018 Social IL-37 is elevated in active adult-onset Still's disease and may be a biomarker of AOSD activity. IL-37 correlates with systemic score, IL-1β, IL-18, and IL-10. IL-37 is an antiiinflammatory cytokine that inhibits IL-18 activity. https://t.co/IFQrOpBKdi
25 Mar 2018 Social FDA Arthritis Advisory Committee tomeet on April 23rd to discuss the NDA for Eli Lilly's JAK inhibitor - baricitinib in moderate to severe RA. Discussion will be around risk:benefit assessment, dose selection & the risk of venous thromboembolic events. https://t.co/dQ4AdYZyQx
25 Mar 2018 Social The RheumNow Week in Review is up on the website https://t.co/uZJI2SoWlL ; or listen to the podcast on your iPhone, iTunes or here https://t.co/3KCu2GjosR
22 Mar 2018 Social Norfolk registry study of 431 inflammatory arthritis pts shows 82% still on MTX after 2 years. Early MTX failure associated with RF+, younger onset age, high DAS-28. MTX D/C for AE less likely if RF-positive https://t.co/kOrfaCnZaf
21 Mar 2018 Social Study from German RABBIT Registry of 885 RA patients treated with tocilizumab finds that treatment success with TCZ similar in pts with no, 1 or 2 prior bDMARD failures, but less with with ≥ 3 bDMARD failures. https://t.co/jAriEaPruP
20 Mar 2018 Social FDA Arthritis Advisory Committee will meet on April 23rd to discuss the NDA for Eli Lilly's JAK inhibitor - baricitinib in moderate to severe RA. Discussion will be around risk:benefit assessment, dose selection & the risk of venous thromboembolic events. https://t.co/dQ4AdYZyQx
19 Mar 2018 Social Flares are frequent in patients in 120 RA undergoing arthroplasty (THA, TKA); by 6 wks 63%. Flare more freq with higher disease activity (OR=2), ESR, CRP, Pain; but not affected by biologic use. https://t.co/4hdn5nTQZO
19 Mar 2018 News Using Synovial Tissue Biopsies to Develop Precision Medicine for Rheumatoid Arthritis
16 Mar 2018 Social The RheumNow Week in Review is UP! Dr. Cush reviews tales from intestinal crypts, the friendly skies & the hips of hockey players. Also the microbiome & lupus, ENT GPA and rare opportunistic infx w/ biologics. https://t.co/tgtkgt8RVe
13 Mar 2018 Social An Italian 89 pt GPA study finds ENT involvement in 72%; tend to be younger w/ less renal disease. Sinonasal sx in 58%,otitis media/otomastoiditis in 35%. ENT involvement predicted better outcomes and milder GPA w/ lower renal dz and mortality rate. https://t.co/UWjzzloxm9
12 Mar 2018 Social Idiopathic pulm fibrosis is assoc with UIP pattern on CT. Connective tissue dz -ILD syndrome should be suspected with 3 CT signs - “straight-edge” sign, “exuberant honeycombing” sign, & “anterior upper lobe” sign - more common in CTD-ILD than IPF https://t.co/fQoOowZgNE
09 Mar 2018 Social The RheumNow Week in Review is Up! Listen here https://t.co/83DtTD8k9L or view it there https://t.co/WpLP2XXFAw
08 Mar 2018 Social Xeljanz (tofacitinib) - No dose adjustment is needed with mild renal impairment. Drug has not been studied in RA/PsA pts with baseline creatinine clearance < 40 mL/ min https://t.co/AvgEzObEAa
07 Mar 2018 Social RT @drhectorchinoy: Mycophenolate safety update from @MHRAgovuk either patient or female partner use reliable contraception on mycophenolat…
06 Mar 2018 Social Study of 176 #RA patients shows that those who eat fish 2 or more times per week have better disease control with significantly lower DAS28 scores. For each additional serving of fish per week, DAS28-CRP was significantly reduced by 0.18. https://t.co/vbsyv0SxSU
05 Mar 2018 Social 30 pts with GCA were assessed by MRA - Less than half had normal MRA at baseline and MRA were weakly sensitive to Clinical change. This preliminary report suggests MRA is NOT useful or predictive in MRA https://t.co/aheWOMKtCE
26 Feb 2018 Social Checkout #RWCS video by rheumatology Fellow Dr. Natasha Zohuri as she presents a cool case of an RA imitator later diagnosed as???? https://t.co/0UIbMajNWx