Friday, 23 Mar 2018

RA/Inflammatory arthritis

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24 Jan 2018 Social Metanalysis of 6 studies 9,045 PM/DM pts shows inflammatory myositis associated with increased risk of Venous Thromboembolic events (OR =4.31) & risk of DVT (OR =4.85) or PE (OR =4.74)
19 Jan 2018 News Weight Loss Linked to RA Improvement
18 Jan 2018 Social RT @jeffsparks: Our latest paper is out showing that weight loss is associated with improved #rheumatoidarthritis disease activity in real-…
17 Jan 2018 News IL-1 and IL-6 Inhibition Preferred in Systemic JIA
15 Jan 2018 Social Cohort study of 204 myositis pts shows 6.4% develop opportunistic infx (OI) - 55% occuring in 1st yr, strongly assoc w/ high dose Steroids, biologics use, fever @onset, 4+ immunosuppressive use
15 Jan 2018 Social Taiwan claims study of 18267 RA patients (vs 73k non-RA) - RA pts have 2 fold increase in Hearing loss; moreso in men, elderly; worse w/ HTN and CV comrobidities. Lower rates seen w/ all RA therapy, NSAIDs, Pred, DMARDs, TNFi
13 Jan 2018 Social RheumNow Wk in Review is Up! Ca/Vit D & Fx, Cost of RA care, Kyrstexxa Sales, Weekly Arava. Chk out podcast
11 Jan 2018 Social Metanalysis of #RA cost of care (12 papers, only1/3 good) -Tot direct medical costs ~ $12,509 for all RA pts; $36,053 for bDMARD users; RA-specific costs were $3,723 all RA patients and $20K for bDMARD users
10 Jan 2018 Social Checkout Dr. Kathryn Dao's #ACR17 video on early RA presentations from ACR 2017 in San Diego.
10 Jan 2018 Social 8,534 FMF Israeli pts were found to have a lower risk of Cancer (SIR 0.66;(95% CI 0.55–0.77). Is inflamm related CA risk different with disorders of adaptive vs innate immunity?
09 Jan 2018 News Increasing Adverse Events Seen with Higher Disease Activity in Early RA
09 Jan 2018 News Small Joint Surgeries Drop Among RA Patients
03 Jan 2018 News Despite Increasing Metric Use, They Are Not Widespread in Rheumatoid Care
03 Jan 2018 Social RA, Type 1 Diabetes & Celiac disease share common genetic links with following genes PTPN22, TNFAIP3, CTLA4
03 Jan 2018 Social Claims data show HBV Testing in RA starting DMARD is low in USA (20.3%) & Taiwan (24.5%), US does >1HBV test (43.4% vs 16.3%) compared w/ Taiwan. MUST do HBsAg, HBcAb, HBsAb, HCV Ab before DMARDs/Biologics
02 Jan 2018 Social Autologous stem cell (ASC) Rx looks favorable for systemic sclerosis ( recent safety review of 18 ASC pts showed 4 death shows a strong need to optimize Pt selection to reduce toxicity.
02 Jan 2018 News Bone Marrow Edema May be Found in Normals, Athletes and Military Recruits
02 Jan 2018 Social CORRONA RA Registry Study of 566 ABA initiators and 1715 TNFi initiators shows that CCP POSITIVITY predicted a good response to Abatacept but not TNFi.
28 Dec 2017 Blog The Story Teller (Best of 2017)
27 Dec 2017 Social Nice Review of the Treatment of idiopathic Inflammatory Myopathies by Parker and Chinoy @drhectorchinoy; Covers MTX, AZA, IVIG, CTX, RTX, calcineurin inhib & biologics. Full text from European Medical Journal.