Friday, 21 Sep 2018

RA/Inflammatory arthritis

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19 Jul 2018 News The Lung in RA: Little Progress
18 Jul 2018 Social Study of 132 Systemic Sclerosis pts shows a significant minority with arthralgia, synovitis, contractures and erosions. RF+ in 15.7% of limited, 9% diffuse & 20% of overlapt pts. Double RF/CCP + assoc w/ arthralgia and erosions https://t.co/NpOKQD1Vqx
17 Jul 2018 News Ultrasound Tenosynovitis Predicts RA Development
17 Jul 2018 Social Retrospective study of 40K newly Dx RA pts shows only half receive DMARD within 12 mos! 53% initiating a DMARD, 2.6% initiating a biologic. Rates did not change between 2009-2012. RxStarts likely w/ POS, RF+, Rheumatologist Dx https://t.co/JtnmU77L2Z
16 Jul 2018 Social RA Adherence to1st bDMARD was suboptimal even in effectively treated pts. Study of 10374 pts, 1 yrs adherence rates = 46%; 2nd Yr = 34%; lowest for golimumab and highest for infliximab. Among 30%, effectively Tx pts, 2yr adherence =59% https://t.co/35vN57DxRW
16 Jul 2018 Social Population study 8 Latin American countries finds among indigenous people the prevalence of MSK/Rheum disorders is 35%: back pain 13%, OA 10%, regional pain 6%, RA 1.3%,and SpA 0.1%. https://t.co/r4y8N2FUrg
15 Jul 2018 Social 5304 pts with back pain, only 124 patients had new‐onset Inflam LBP (IBP). After 13 yrs, only 31% of IBP progressed to SpA; That IBP often resolves may explain difference betw prevalence of IBP (3–6%) & the prev of SpA (0.4–1.3%) https://t.co/e1OeflZuaU
13 Jul 2018 News The Diverse Fate of Seronegative Rheumatoid Arthritis
12 Jul 2018 Social From 5304 pts with back pain, only 124 patients had new‐onset Inflam LBP (IBP). After 13.2 yrs, only 31% of IBP progressed to SpA; That IBP often resolves may explain difference betw prevalence of IBP (3–6%) & the prev of SpA (0.4–1.3%) https://t.co/e1OeflZuaU
11 Jul 2018 Social RT @ARD_BMJ: Absence of ultrasound inflammation is associated with no subsequent radiographic progression, while being in ACR/EULAR Boolean…
11 Jul 2018 Social Canadian population studies shows that hyperlipidemia monitoring (mostly by PCPs) was poor for 5587 RA and 5613 controls; Lipids were measured in 56.6 and 59.5%, respectively https://t.co/gPRf8fIqHf
09 Jul 2018 Social Early Arthritis Clinic in Australia (2008-15) shows significant delays: Sx onset to rheumatology review = 26.4 wks. Patient delay (8.7 wks) was the longest delay-predicted overall delay. Tx Delays assoc w/ lower Dz severity & socioeconomic disadvantage https://t.co/giLD90q76K
09 Jul 2018 Social 76 early RA pts in remission at 1 year were studied (including MRI) at baseline and at 12 months. Despite remission a majority had MRI inflammation (43% synovitis, 39% BM edema, 9% tenosynovitis), and 33% showed MRI progression of bone erosions. https://t.co/VTVxTXXtcU
05 Jul 2018 Social My Approach to Difficult RA, some different thoughts/approaches, 7 drugs you've never used and more https://t.co/IyQ90A7nlU
04 Jul 2018 Social The diagnosis of Still’s disease (SJIA) hinges on what pathology? RheumNow Live Vote - 4Q survey for Rheumatologists only - https://t.co/uUwxEiccmr
04 Jul 2018 Social Systemic JIA (Still’s disease) is driven by which cytokine? TNF, IL-1, IL-6, or IL-18. Rheumatologist Survey – answer here >> https://t.co/uUwxEiccmr
03 Jul 2018 Blog Best of 2017: Rules for Drug Cessation with Infection
03 Jul 2018 Social Which Cytokine is most important in the pathogenesis of systemic JIA (Still’s disease). RheumNow Survey for RHEUMATOLOGISTS - please vote here>> https://t.co/uUwxEiccmr
02 Jul 2018 Social How do Rheumatologists diagnose Still’s disease (SJIA) A Rheumatologist survey - Make Your views count; RHEUMS vote HERE https://t.co/uUwxEiccmr
02 Jul 2018 Social In early arthritis clinics in Leeds and UK ERAS study (454 &895 pts), DMARD free remission seen in 15-9.4%; predictors included acute onset, short Sx duration, NO smoking, No Xray damage, Seronegativity, absent HLA shared epitope alleles https://t.co/3yulHyrS4O