Wednesday, 21 Nov 2018

RA/Inflammatory arthritis

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12 Sep 2018 News Mediterranean Diet Reduces Risk of Rheumatoid Arthritis
11 Sep 2018 Social 12 mos study (U-Act-Early) 108 Rx naive RA patients were treated in a T2T manner w/ MTX and then HCQ and tofacitinib added after 6 mos w/ inadequate response. @12 mos IR was seen in 52% and predicted by Higher DAS28, current smoking and no alcohol intake https://t.co/mkaNQ8AyME
10 Sep 2018 Social Gilead and Galapagos Announce TORTUGA Phase 2 Study of Filgotinib (JAK 1 inhib) in Ankylosing Spondylitis with filgotinib ASAS20 response of 76% vs 40% PBO response (p<0.0001). https://t.co/0s8xc8za4h
10 Sep 2018 Social #Scleroderma Research Foundation will collaborate with 11 US universities in establishing CONQUER: a national, longitudinal patient registry for scleroderma. Leaders include Victoria Shanmugan (GWU), Jessica Gordon (HSS), & Shervin Assassi (UT Houston) https://t.co/lKs4W14iNI
10 Sep 2018 Social Red cell distribution width RDW interpretation is a useful tool in clinical practice to distinguish between articular inflammatory and non‐inflammatory joint diseases, as with CRP. RDW seems to be a surrogate marker of the inflammatory process. https://t.co/Z2Ql5FZMxH
10 Sep 2018 Social 325 pts with Early RA received either MTX or MTX + HCQ. At 6 mos the combination MTX/HCQ patients had signifificantly greater EULAR good responses and DAS28-CRP values; but differences were less by 12 mos. Rx intensification was more in MTX monoRx group https://t.co/zTy0KNx1X7
05 Sep 2018 Social RT @DrPetryna: Rheum disease associated secondary MAS does not only happen in auto-inflammatory syndromes; it can complicate virtually any…
31 Aug 2018 Social Unmet Needs in in Still’s Disease -results of 257 Rheum Survey on how to treat, when to use biologic, best biologic & more. Did you know that 20% of Rheums dont see Stills and 60% of referrals from PCP, Hospitalists & ID Docs https://t.co/iv300uSO8J’s-disease#.W4iPBanKroM.twitter
29 Aug 2018 Social My observation is that new consults who present for joint issues while on ADHD meds are likely to have sleep and myofascial pain problems (alone or in addition to other findings)
26 Aug 2018 Social Adult, Acute, Asymmetric Oligoarticular inflammatory arthritis - Whats your differential Dx? PsA, Spa, Reactive, IBD, Sarcoid, undifferentiated arthritis, CPPD, RA, chlamydia, Lyme ? Dont forget Gout, gonococccal Arthritis, TB!
24 Aug 2018 Social Treatments Do Not Increase Infection Risk in Ankylosing Spondylitis | RheumNow - Rheumatology News & Information https://t.co/YTvDyOAzSN
24 Aug 2018 Social Study of 21 pts w/ cutaneous polyarteritis nodosa (PAN), 40% relapsed; Predictors of relapse included elevated CRP, ANC, neutrophil-to-lymphocyte ratios, and elevated systemic immune-inflammation indices. https://t.co/9tyEl1NjF2
23 Aug 2018 Social Comparative study of pregnant women with RA (n=657), JIA (170) vs 564 controls shows RA and JIA have 2 fold higher rates of pre-term delivery and risk of PTD was highest w/ RA activity and corticosteroid use. https://t.co/FPmtPbtxUM
23 Aug 2018 Social 1st Ceremonial Burial of Dead Words in Rheumatology - The Rheumatology Dead Word Cemetary (CTD, Rheumatism, CREST, MCTD, and more) https://t.co/k3f5HgCCiQ
22 Aug 2018 Social Adult, Acute, Asymmetric Oligoarticular inflammatory arthritis - Whats your differential Dx? PsA, Spa, Reactive, IBD, Sarcoid, undifferentiated arthritis, CPPD, RA, chlamydia, Lyme ?
20 Aug 2018 Slide of the day Dealing with Comorbidities
19 Aug 2018 Social Swedish Registry study of 2631 RA pts with Cancer - 20% received TNFi , rest did not. There was no increase in cancer recurrence on TNFi (HR 1.06; 95% CI, 0.73 to 1.54). Rheums should treat aggressively the arthritis and leave cancer to the oncologist https://t.co/2Na7OeGqnE
16 Aug 2018 News Early Exposure to Passive Smoke May Up Risk for RA Later in Life
15 Aug 2018 News Tumor Necrosis Factor Inhibitors Do Not Increase the Risk of Cancer Recurrence
13 Aug 2018 News Cardiovascular Benefits of Maintaining Biologic Therapy