Thursday, 20 Feb 2020

RA/Inflammatory arthritis

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23 Jan 2020 Social RT @hausmannMD: 60% The percentage of patients at @NIH's autoinflammatory disease cohort that are undifferentiated and do not have a specif…
23 Jan 2020 Social In 80 RA pts, SJC & TJC flares seen in 36% of pts. Pt-reported flares usually reflected incr Dz activity (MD exam & US). Pts & clinicians agreed in 79–93% of joints, moreso SJ than TJ. Using US, there was high specificity (>86%) & low sensitivity (<34%)
23 Jan 2020 Social #UTSW Dr Lauren Nassi on JIA - enthesitis related arthropathy or ERA. 80% are B27+. May develop AS or SpA much later. They respond very well to TNF inhibitors
23 Jan 2020 Social #UTSW Dr Lauren Nassi on JIA - long term outcomes in Oligoarticular jia is not so benign. Half go on to polyarticular disease
23 Jan 2020 Social #UTSW Dr Lauren Nassi on JIA- red flags with Oligoarticular JIA Painful joint Hip involvement High acute phase reactants
23 Jan 2020 Social #UTSW Rheum GR Rounds Dr Lauren Nassi on JIA - JIA accounts for 50-70% of all cases in a pediatric rheum clinic
22 Jan 2020 News Low Risk of Inflammatory Arthritis in Hidradenitis Suppurativa Patients
19 Jan 2020 Social RT @ACR_Journals: Early View from Arthritis Care & Research: Association of Seropositivity and Mortality in Rheumatoid Arthritis and the I…
17 Jan 2020 Social RT @drdavidliew: The future is bedside-to-bench: "Systemic comparison (of immunotherapy irAEs) with canonical forms of (inflamm arthritis).…
17 Jan 2020 Social The RheumNow Podcast is up! Steroids and organ damage; same day hip replacments? Tulips and d-Dimers. Watch in on RheumNow>> or listen to the podcast in your car on Android Auto, Apple car play or
17 Jan 2020 Social 23% of RA patients have moderate-to-severe Obstructive Sleep Apnea (AHI ≥ 15) - study of RA patients 199 patients underwent PSG, OSA is more common in RA than in the general population, but there is no relationship with disease activity.
17 Jan 2020 Social Actress Tatum O'Neal, 56, was diagnosed with rheumatoid arthritis at age 50, but had symptoms for almost 10 years.
13 Jan 2020 Social 128 pts w/ Breast Cancer were evaluated for rheumatic complaints. Ultimately 1/3 developed an inflammatory rheumatic disease; most common being RA (8%), Sjogrens (6%) & PsA (5%). Arthralgias were more common with aromatase inhibitor use.
10 Jan 2020 Social UK study of 2701 Early arthritis pts Dx in 3 different eras finds that from those dx in 2010, 59% were estimated to reach low disease activity compared with 48% with diagnosis in 2002 and 32% with diagnosis in 1990.
09 Jan 2020 Social JAMA Case challenge: 61yoM with seronegative RA x yrs (rx w/ MTX and biologics) develops intermittent fever (38C), asymmetric polyarthralgias, & 50 lb Weight Loss, CRP 7.7mg/L. No response to TCZ and developed diarrhea. What do you do next?
09 Jan 2020 Social Dr. Heidi Jacobi #UTSW says limited SSc has slowly progressive skin thickening of the distal extremities but also the face and neck.
09 Jan 2020 Social Dr. Heidi Jacobi #UTSW says Raynauds, puffy digits and a +ANA should raise suspicion of systemic sclerosis. Also Carol tunnel syndrome may be a presenting feature
07 Jan 2020 Social CORRONA registry 880 RA pts developed a solid cancer. 42% taking bDMARD/tsDMARD; 5% switched biologics w/in 36 mos & 10% started a new biologic- w/ most changing to a TNFi (53%). ACR guidelines say to Rx regardless of solid tumor
07 Jan 2020 Social high-dose trivalent inactivated influenza vaccine (HD-TIV) was studied in 696 RA patients compared to standard-dose quadrivalent flu vaccine - Seroconversion was 3 fold higher w/ HD-TIV, no differences in side effects and no increase in RA flares
06 Jan 2020 Social Claims data from RA patients (n = 12,182), shows that screening for hyperlipidemia was suboptimal (compared to Diabetes pts), Those seeing a PCP and Rheum were 36% more likely to be screened.