Thursday, 20 Feb 2020

RA/Inflammatory arthritis

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23 Jan 2020 Social RT @hausmannMD: 60% The percentage of patients at @NIH's autoinflammatory disease cohort that are undifferentiated and do not have a specif…
23 Jan 2020 Social In 80 RA pts, SJC & TJC flares seen in 36% of pts. Pt-reported flares usually reflected incr Dz activity (MD exam & US). Pts & clinicians agreed in 79–93% of joints, moreso SJ than TJ. Using US, there was high specificity (>86%) & low sensitivity (<34%) https://t.co/jMRQg5fUuS
23 Jan 2020 Social #UTSW Dr Lauren Nassi on JIA - enthesitis related arthropathy or ERA. 80% are B27+. May develop AS or SpA much later. They respond very well to TNF inhibitors
23 Jan 2020 Social #UTSW Dr Lauren Nassi on JIA - long term outcomes in Oligoarticular jia is not so benign. Half go on to polyarticular disease https://t.co/eRv52dtyZY
23 Jan 2020 Social #UTSW Dr Lauren Nassi on JIA- red flags with Oligoarticular JIA Painful joint Hip involvement High acute phase reactants
23 Jan 2020 Social #UTSW Rheum GR Rounds Dr Lauren Nassi on JIA - JIA accounts for 50-70% of all cases in a pediatric rheum clinic
22 Jan 2020 News Low Risk of Inflammatory Arthritis in Hidradenitis Suppurativa Patients
19 Jan 2020 Social RT @ACR_Journals: Early View from Arthritis Care & Research: Association of Seropositivity and Mortality in Rheumatoid Arthritis and the I…
17 Jan 2020 Social RT @drdavidliew: The future is bedside-to-bench: "Systemic comparison (of immunotherapy irAEs) with canonical forms of (inflamm arthritis).…
17 Jan 2020 Social The RheumNow Podcast is up! Steroids and organ damage; same day hip replacments? Tulips and d-Dimers. Watch in on RheumNow>> https://t.co/QY3qxTEYv0 or listen to the podcast in your car on Android Auto, Apple car play or https://t.co/3aCQ6qEJPx
17 Jan 2020 Social 23% of RA patients have moderate-to-severe Obstructive Sleep Apnea (AHI ≥ 15) - study of RA patients 199 patients underwent PSG, OSA is more common in RA than in the general population, but there is no relationship with disease activity. https://t.co/noojvYmtMk
17 Jan 2020 Social Actress Tatum O'Neal, 56, was diagnosed with rheumatoid arthritis at age 50, but had symptoms for almost 10 years. https://t.co/DotJHTLU3h
13 Jan 2020 Social 128 pts w/ Breast Cancer were evaluated for rheumatic complaints. Ultimately 1/3 developed an inflammatory rheumatic disease; most common being RA (8%), Sjogrens (6%) & PsA (5%). Arthralgias were more common with aromatase inhibitor use. https://t.co/d9CqWfRrXD
10 Jan 2020 Social UK study of 2701 Early arthritis pts Dx in 3 different eras finds that from those dx in 2010, 59% were estimated to reach low disease activity compared with 48% with diagnosis in 2002 and 32% with diagnosis in 1990. https://t.co/rn2cYLID6V
09 Jan 2020 Social JAMA Case challenge: 61yoM with seronegative RA x yrs (rx w/ MTX and biologics) develops intermittent fever (38C), asymmetric polyarthralgias, & 50 lb Weight Loss, CRP 7.7mg/L. No response to TCZ and developed diarrhea. What do you do next? https://t.co/QkGca1qp9r
09 Jan 2020 Social Dr. Heidi Jacobi #UTSW says limited SSc has slowly progressive skin thickening of the distal extremities but also the face and neck.
09 Jan 2020 Social Dr. Heidi Jacobi #UTSW says Raynauds, puffy digits and a +ANA should raise suspicion of systemic sclerosis. Also Carol tunnel syndrome may be a presenting feature
07 Jan 2020 Social CORRONA registry 880 RA pts developed a solid cancer. 42% taking bDMARD/tsDMARD; 5% switched biologics w/in 36 mos & 10% started a new biologic- w/ most changing to a TNFi (53%). ACR guidelines say to Rx regardless of solid tumor https://t.co/pPgnYNdT7Q
07 Jan 2020 Social high-dose trivalent inactivated influenza vaccine (HD-TIV) was studied in 696 RA patients compared to standard-dose quadrivalent flu vaccine - Seroconversion was 3 fold higher w/ HD-TIV, no differences in side effects and no increase in RA flares https://t.co/1JBs95vGSA
06 Jan 2020 Social Claims data from RA patients (n = 12,182), shows that screening for hyperlipidemia was suboptimal (compared to Diabetes pts), Those seeing a PCP and Rheum were 36% more likely to be screened. https://t.co/j661loTDGk