Wednesday, 01 Apr 2020

RA/Inflammatory arthritis

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17 Jan 2020 Social 23% of RA patients have moderate-to-severe Obstructive Sleep Apnea (AHI ≥ 15) - study of RA patients 199 patients underwent PSG, OSA is more common in RA than in the general population, but there is no relationship with disease activity. https://t.co/noojvYmtMk
17 Jan 2020 Social Actress Tatum O'Neal, 56, was diagnosed with rheumatoid arthritis at age 50, but had symptoms for almost 10 years. https://t.co/DotJHTLU3h
13 Jan 2020 Social 128 pts w/ Breast Cancer were evaluated for rheumatic complaints. Ultimately 1/3 developed an inflammatory rheumatic disease; most common being RA (8%), Sjogrens (6%) & PsA (5%). Arthralgias were more common with aromatase inhibitor use. https://t.co/d9CqWfRrXD
10 Jan 2020 Social UK study of 2701 Early arthritis pts Dx in 3 different eras finds that from those dx in 2010, 59% were estimated to reach low disease activity compared with 48% with diagnosis in 2002 and 32% with diagnosis in 1990. https://t.co/rn2cYLID6V
09 Jan 2020 Social JAMA Case challenge: 61yoM with seronegative RA x yrs (rx w/ MTX and biologics) develops intermittent fever (38C), asymmetric polyarthralgias, & 50 lb Weight Loss, CRP 7.7mg/L. No response to TCZ and developed diarrhea. What do you do next? https://t.co/QkGca1qp9r
09 Jan 2020 Social Dr. Heidi Jacobi #UTSW says limited SSc has slowly progressive skin thickening of the distal extremities but also the face and neck.
09 Jan 2020 Social Dr. Heidi Jacobi #UTSW says Raynauds, puffy digits and a +ANA should raise suspicion of systemic sclerosis. Also Carol tunnel syndrome may be a presenting feature
07 Jan 2020 Social CORRONA registry 880 RA pts developed a solid cancer. 42% taking bDMARD/tsDMARD; 5% switched biologics w/in 36 mos & 10% started a new biologic- w/ most changing to a TNFi (53%). ACR guidelines say to Rx regardless of solid tumor https://t.co/pPgnYNdT7Q
07 Jan 2020 Social high-dose trivalent inactivated influenza vaccine (HD-TIV) was studied in 696 RA patients compared to standard-dose quadrivalent flu vaccine - Seroconversion was 3 fold higher w/ HD-TIV, no differences in side effects and no increase in RA flares https://t.co/1JBs95vGSA
06 Jan 2020 Social Claims data from RA patients (n = 12,182), shows that screening for hyperlipidemia was suboptimal (compared to Diabetes pts), Those seeing a PCP and Rheum were 36% more likely to be screened. https://t.co/j661loTDGk
06 Jan 2020 Social From the 9/11 World Trade Center registry, 118 persons found w/ a CTD (RA=71, Sjӧgrens 22, SLE 20, myositis 9,MCTD 7, PSS 4. Responders w/ intense dust cloud exposure had 2 fold CTD risk & Community members w/ PTSD had 3‐fold risk. https://t.co/07GhloezNA
04 Jan 2020 Social 2019 YEAR IN REVIEW Podcast is up! Superheros, women, New Drugs, Novel Approaches, Failed drugs, MTX, Who's killing medicine & low dose pred Watch here>> https://t.co/sYb3KvivJK or Podcast Listen on iTunes https://t.co/FlPe6BQ3BW or Soundcloud >> https://t.co/FlPe6BQ3BW
02 Jan 2020 Social Rates of "indeterminate" results on quantiferon-IT assays were found to be significantly higher in systemic vasculitis (21%) than nonvasculitis pts and controls (7-7.5%). Indeterminate predictors were Syst vasculitis (OR 9.64), high NLR (OR 1.70). https://t.co/roZINmKgZ1
02 Jan 2020 Social anti-MDA5+ amyopathic dermatomyositis (ADM) with ILD is severe and refractory. NEJM letter reports on 18 ADM Rx w/ tofacitinibs who showed better 6 mo survival (100% vs 78%) (P=0.04) and improved ferritin, FVC, DLCO, & CT Chest over time. https://t.co/H8JPkVrQqR
02 Jan 2020 News Best of 2019 - War on RA - Part 1: Walk on the Moon
31 Dec 2019 Social Study of 182 hospitalized adult-onset Still's disease patients shows predictive factors for developing macrophage activation syndrome to include: 1. Splenomegaly (OR 5.7), 2. pericarditis (OR 6.5), and 3. ferritin >2000 (OR 4.7). https://t.co/CNcIDrbU77
31 Dec 2019 News Best of 2019 - War on RA - Part 3: Useless Drugs
30 Dec 2019 Social Im starting a War on RA. I need you go get mad. Read it here https://t.co/oIekFqSZVN or watch it here https://t.co/4mBzQBSys0
27 Dec 2019 Social The Best Rheums go to the Best Meetings - RHEUMNOW LIVE - March 13-14-15 2020 Great Venue =Fort Worth. Short Lectures, interactive sessions, Q&A panels, TED (like) Talks, digital, streaming and much more. You dont want to miss this meeting! https://t.co/69Y3QyU3Wc
27 Dec 2019 Social Study of 690 ambulatory patients examined RDW, ESR, CRP and showed RDW is increased in inflammatory disorders (RA, SpA) and elevated RDW has a 48–95% sensitivity and 66–95% specificity for inflammatory disease. https://t.co/dSdG1WTJY8