Monday, 26 Jun 2017

RA/Inflammatory arthritis

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22 Mar 2017 Social Review of Chikungunya virus arthritis: Begins w/ fever, then rash;myalgia, arthralgia, <60% chr inflam polyarthritis
20 Mar 2017 Social #RA pts admitted to ICU w/ sepsis are more likely to have shock & severe sepsis, & more 3 yr mortality than non-RA
16 Mar 2017 News FDA Invites Open Commentary on Biosimilar Interchangeability
14 Mar 2017 Social CORRONA proves a "Window of Opportunity" - shorter Dz duration (<2yrs) assoc w/ greater ΔCDAI & LDA w/ abatacept Rx
10 Mar 2017 Social ESPOIR 602 Early RA study x7yrs: 2/3 on Pred. Low dose pred use not assoc w/ more AE, infx, HTN; but more Drug use.
09 Mar 2017 News Oral Bacteria Driving ACPA and Rheumatoid Arthritis
07 Mar 2017 Social Unmonitored Biologic DMARD discontinuation (w/o restarts) yields high flare rates, worse function, more Xray damage
07 Mar 2017 News Non-Ischemic Heart Failure in Rheumatoid Arthritis
06 Mar 2017 Social Women infected the Zika virus have a >20 fold greater risk of babies with (compared to before Zika epidemic).
05 Mar 2017 Social In TNFi failure RA patients Secukinumab is modestly better than PBO (~30% vs 18%) but not as good as ABAtacept (43%)
03 Mar 2017 News Psychologic Impact of Rheumatoid Arthritis on Men
02 Mar 2017 News Novel Mechanisms for Rheumatoid Arthritis
01 Mar 2017 Social Sternoclavicular arthritis is septic in 7.3%; extraarticular infection, cirrhosis & cancer are(2-4fold) risk factors
01 Mar 2017 News Rheumatoid Progression Slowing Down
27 Feb 2017 Social Study of 550 RA pts shows RA assoc ILD more likely w/ age, smoking, elevated LDH and RF positivity.
27 Feb 2017 Social Computational analysis reveals 8 genes underlying an inverse relationship between schizophrenia & #RA.
25 Feb 2017 Social Rheumatoid arthritis worldwide (8MM) market set to grow from $19.5 billion (in 2015) to $28.5B by 2025
24 Feb 2017 Social Review article on negative regulators of JAK/STAT signaling in #RA and #osteoarthritis.
24 Feb 2017 Social ?Which of following most influences risk of getting #RA? A) 1st degree relative w/ RA; B) RF 34 IU; C) CCP >250 IU; D) CarbP Ab+ (answer=C)
24 Feb 2017 Social Switched memory B Cells in RA spont make ACPA and correlate highly w/ serum anti-CCP3 (r=0.57)