Tuesday, 18 Jun 2019

TNF inhibitor

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09 May 2019 Social Analysis of claims data compared hospitalized infection rates among 11,248 matched pairs of new initiators of abatacept or TNF inhibitors. Serious hosp infections were significantly lower in ABA vs infliximab (HR 0.63; 0.47-0.85), but similar to ETN & ADA https://t.co/JhXlC7p1A7
29 Mar 2019 News FDA Approves Cimzia for Non-Radiographic Axial Spondyloarthritis
13 Mar 2019 News Lower TNF Inhibitor Persistence in Spondylitis
22 Feb 2019 News The Risk of Tuberculosis with TNF Inhibitors
11 Feb 2019 ACR Video QD Clinic - Breast Cancer & a TNF Inhibitor
06 Feb 2019 Social The EMAs CHMP has issued a eceived a positive opinion for 2 TNF inhibitor biosimilars: Idacio (adalimumab) and Kromeya (adalimumab). For the treatment of select inflammatory and autoimmune disorders https://t.co/lz7EvtTcTB
24 Jan 2019 Social Using FMF-KI knockout mice (high TNF levels) researchers find TNF signaling drives pyrin & inflammasome activation; TNF is a critical modulator of pyrin of pyrin-inflammasomopathies like FMF. This is why TNF inhib sometimes work in inflammasomopathies. https://t.co/0EvuTI57tn
19 Dec 2018 Social Study from the UK BSRBR registry shows 34 cancers & 41 deaths in 709 pts. Risk of CA w/ TNFi was not increased (SIR 0.94; 95% CI 0.65,1.34) (but for 2 fold incr risk of nonmelanoma skin CA) & all-cause mortality rate was increased (SMR 1.56) from CV events https://t.co/6HSnw5SOF8
25 Oct 2018 Social RT @WIRheum: MTB screening in patients on TNFi When to re-screen? Neg to pos conversion discovered in a small number of cases Often in p…
25 Oct 2018 Social RT @NicoleBitencou5: Use of antiTNF in childhood does NOT appear to increase risk of malignancy in adults according to Medicare claims data…
23 Oct 2018 ACR Video Dr. Janet Pope: TB Testing and TNF Inhibitors
21 Aug 2018 Social TB Study of 550 RA, PsA, AS patients on TNF inhibitors from Romania (population risk is 97 per100k PY): incidence of TB on TNFi to be 1348.0, 862.1 and 540.2 per 100k Pt-Yrs (measured as TST >5, TST>10mm, QFT) https://t.co/SIkefJg909
03 Aug 2018 News Higher Infection Rates for Infliximab in Psoriasis
19 Jul 2018 News Biomarker Combo Predicts TNF Inhibitor Responses
12 Jun 2018 News TNF Inhibitors Don't Increase Cancer Risk in Children
11 Jun 2018 News Risk of Psoriasis Complicating TNF Inhibitor Therapy
09 Apr 2018 News Favorable Certolizumab Safety Profile in Pregnancy
05 Mar 2018 News Severe Stevens-Johnson and Toxic Epidermal Necrolysis Syndromes May Respond to Etanercept
20 Feb 2018 News Pediatric Use of TNF inhbitors Does Not Increase Malignancy Risk
20 Feb 2018 Social PANTS study:Personalized anti-TNF Therapy in Crohn Disease tests real-world eficacy, safety & immunogenicity of infliximab vs biosimilar CT- P13 vs adalimumab. Wk 54 remission rate was 40% INFX, 40% CTP13 & 34% in ADA; immunogenicity was 26%, 28%, 11% https://t.co/irhImH6ipP