Friday, 15 Dec 2017

TNF inhibitor

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18 Apr 2015 Social Listeria outbreaks recently. @risk Pts include infliximab, otherTNFi, MTX & Pred; rarely RTX or ABA, Mortality 11-27% http://buff.ly/1DVjSsR 
04 May 2015 News DRESS Trial Shows TNFi Dose Reduction is Possible - Without Major Flares
14 May 2015 News Hepatotoxicity and TNF Inhibitors
14 May 2015 Social RheumNow: Major liver toxicity is rare with TNF inhibitors, minor LFTs are common. http://t.co/bJAmMFxJvq
17 May 2015 News Adalimumab Gets FDA Orphan Drug Status for Use in Hidradenitis Suppurativa
20 May 2015 Social TNFi Rx RA patients who also took MTX, had a significantly lower risk (64% less) for future large joint replacement. http://t.co/CQ211se7je
22 May 2015 News Amgen & Abbvie Increase the Price of TNF Inhibitors
27 May 2015 News Nonadherence to Self-Injected Biologics is High
28 May 2015 Social Pt directed TNFi dose reduction in 58 Ank Spondylitis pts 94% effective @6 mos but only maintained in 54% over 2 yrs http://t.co/ALU5YezW6t
05 Jun 2015 News Conventional DMARDs extend TNF inhibitor drug survival in patients with spondyloarthropathies
15 Jun 2015 Social #EULAR2015 OPTTIRA study: 97 LDAS RA pts (#SAT0150) tapered TNFi by 1/3 ->14% flares, 2/3-> 34% flares. 45% D/C TNFi http://t.co/hE5aHROD6P
18 Jun 2015 News Frequency of Infliximab Infusion Reactions
23 Jun 2015 News Adherence to ETN/MTX is Greater Than Triple DMARD Therapy
29 Jun 2015 Social EU approves Simponi for Rx of adults with severe, non-radiographic axial spondyloarthritis, based on GO-AHEAD study. http://t.co/FqnMq2MpIY
30 Jun 2015 News Utility of Drug Levels and Anti-Drug Antibodies When Starting TNF inhibitors
01 Jul 2015 Social EMA recommends Humira for Rx of hydradenitis suppurativa based on >6000 pts. FDA granted orphan status in May 2015 http://t.co/WNn9ed3bXB
05 Jul 2015 Social Hospira's Infectra biosimilar sold at 45% discount by a major French hospital group covering 1/4 of French population http://t.co/KSQoi6hG29
05 Jul 2015 News Adalimumab Drug Levels Predict Efficacy
08 Jul 2015 Social TNF inhib use causes steatohepatitis? VA report 8 pts shows TNFi, MTX & PNPLA3 gene mutations may be risks for NAFLD http://t.co/HuxmtZsU62
08 Jul 2015 News Neurologic Events with TNF Inhibitor Therapy