Wednesday, 22 Jan 2020

TNF inhibitor

Date Typesort descending Title Save
07 Dec 2015 Social RA on TNFi: 53% nonadherent, 20% markedly so. Nonadherence assoc w/ Low dz activity, comorbidity, age, MD-Pt discord https://t.co/ixsMCYad8R
30 Mar 2016 Social @RonanTKavanagh Fear of unknown is reason to ask for help (didnt happen). Stopping biologics will results in flare. Inflamm +XRT = bad news
08 Nov 2017 Social RT @uptoTate: 84% of cardiac sarcoidosis pts refractory to immunosuppressive tx responded to TNFi. #ACR17 @RheumNow #2904 https://t.co/vTOL…
26 Oct 2016 Social In Ireland, Pfizer has cut the price of Enbrel to match the price of Benepali - an ETN biosimilar. https://t.co/AKdp5bhHoc
19 Dec 2018 Social Study from the UK BSRBR registry shows 34 cancers & 41 deaths in 709 pts. Risk of CA w/ TNFi was not increased (SIR 0.94; 95% CI 0.65,1.34) (but for 2 fold incr risk of nonmelanoma skin CA) & all-cause mortality rate was increased (SMR 1.56) from CV events https://t.co/6HSnw5SOF8
09 Mar 2017 Social Analysis of FDA FAERS database shows TNF inhibitor ISRs are lower in pts >70yrs & lower when TNFi combined w/ MTX https://t.co/B4t6ivsQDG
22 Oct 2015 Social Goofiest report of the week: Blueberries augment etanercept effects in JIA - plausible but still goofy. https://t.co/OjsAsXpDWQ
18 Sep 2016 Social TNFi induced Psoriasis can be treated w/ TNFi D/C, another TNFi (48-85% recurrence) or Stelara. Good short review https://t.co/t2Hb7kA4ru
20 May 2015 Social TNFi Rx RA patients who also took MTX, had a significantly lower risk (64% less) for future large joint replacement. http://t.co/CQ211se7je
24 Jan 2017 Social Janssen has applied to FDA for new indications (AS, PsA) for golimumab based on GO-ALIVE, GO-VIBRANT trials https://t.co/qTZMJtWmya
09 May 2019 Social Analysis of claims data compared hospitalized infection rates among 11,248 matched pairs of new initiators of abatacept or TNF inhibitors. Serious hosp infections were significantly lower in ABA vs infliximab (HR 0.63; 0.47-0.85), but similar to ETN & ADA https://t.co/JhXlC7p1A7
14 Jul 2015 Social ESPGHAN cautions on biosimilar use; studies on safety & immunogenicity should be mandatory in children w/ IBD http://t.co/Gpa6HmP2U5
22 Apr 2017 Social FDA approves another infliximab biosimilar - Renflexis (Infliximab-abda) from Bioepis, distributed in US by Merck. https://t.co/r74qr73XaI
24 Mar 2016 Social 1st TNFi H2H results are in: EXXELERATE study Cimzia vs Humira shows equal ACR20 @3mo (69 v 71%) & LDAS @2y(35 v 33) https://t.co/qvcQdnAlxy
06 Nov 2017 Social RT @uptoTate: Anti-TNF drugs could be safe following paternal exposure in pregnancy outcomes. #ACR17 @RheumNow #1312 https://t.co/G4s9zyOhoY
09 Jun 2016 Social Do all TNFi work the same way? J Exp Med article suggests unique Humira MOA, expanding functional Foxp3+ Treg cells https://t.co/2zf6u8Q39J
25 Oct 2018 Social RT @NicoleBitencou5: Use of antiTNF in childhood does NOT appear to increase risk of malignancy in adults according to Medicare claims data…
04 Mar 2017 Social RT @ACRheum: #Biosimilars: What Do Patients Need to Know? Read the Q&A blog post from @AngusWorthing & @ACRSimpleTasks → https://t.co/GP9wC…
15 Sep 2015 Social Health Canada is reviewing few reports of schizophrenia & psychiatric dz associated with Enbrel use. http://t.co/pAFr2CSE1k
22 May 2017 Social Survey of 364 UK RA pts shows that giving info on TNFi helps 1/3 and scares 1/3. Many misconceptions about safety https://t.co/lM8gxjjulk