Wednesday, 18 Sep 2019

TNF inhibitor

Date Typesort ascending Title Save
01 Mar 2016 Social Prior hx of Cancer in IBD patients does not preclude the use of TNF inhibitors. https://t.co/D58N3Jj2cQ
30 Apr 2016 Social Metanalysis: TNFi assoc w/ increase risk of perioperative infx (SSI): BUT risk decreases >38% w/ temporary cessation https://t.co/PdZ1QLidvN
26 Jan 2018 Social RheumNow Wk in Review is up. Discussing MPO bronchiectasis, $$ biologics, comorbidity in myositis, secondary TNF failure & ADAbs. Listen here https://t.co/wmVyjrzOB1 Watch there https://t.co/32q2qojDZC
10 Mar 2017 Social 2015 study of 4504 IBD pts shows TNFi use has 2 fold risk of central demyelinating Dz, w/ absolute risk 3.9/10000 PY https://t.co/v0MMvasUic
01 Jul 2015 Social EMA recommends Humira for Rx of hydradenitis suppurativa based on >6000 pts. FDA granted orphan status in May 2015 http://t.co/WNn9ed3bXB
24 Jan 2019 Social Using FMF-KI knockout mice (high TNF levels) researchers find TNF signaling drives pyrin & inflammasome activation; TNF is a critical modulator of pyrin of pyrin-inflammasomopathies like FMF. This is why TNF inhib sometimes work in inflammasomopathies. https://t.co/0EvuTI57tn
08 Nov 2015 Social RT @DrPetryna: #ACR15 #yearinreview TNFi tapering is more successful than complete TNFi withdrawal in established RA pts @RheumNow
24 Oct 2016 Social J&J will compete w/ price of Inflectra through a variety of innovative contracting options, discounts & rebates to payers, providers, & PBMs
07 Nov 2017 Social RT @DrPetryna: #2453 #acr17 no difference in disease activity&PRO with ADA after MTX d/c at 6mo:LDA 42%ADAvs40%ADA+MTX @RheumNow https://t.…
22 Jul 2015 Social Comparative biologic risk of TB Among 75000 pts: 31 TB due to TNFi, 1 w/ ABA; none w/ RTX, TCZ, Tofa, ustekinumab http://t.co/cG8ranlUCN
07 Dec 2015 Social Amgen filed its application for ABP-501 (Humira biosimilar) for approval w/ the EMA; includes Pso, RA, switch data https://t.co/Rfr6Z3XYQt
16 Sep 2016 Social Humira price has increased 6% q 3month for 3 yrs - now $15 billion/yr in USA - what wil happen when biosimilars hi https://t.co/gmX8TeD4ll
28 Apr 2016 Social Metanalysis: TNFi assoc w/ increase risk of perioperative infx (SSI): BUT risk decreases >38% w/ temporary cessation https://t.co/yuSudErjlj
08 Mar 2017 Social Case and Review- Etanercept and other TNFi can be safely used to treat HIV positive patients. https://t.co/Ak0YE8XuuO
29 Jun 2015 Social EU approves Simponi for Rx of adults with severe, non-radiographic axial spondyloarthritis, based on GO-AHEAD study. http://t.co/FqnMq2MpIY
25 Oct 2018 Social RT @WIRheum: MTB screening in patients on TNFi When to re-screen? Neg to pos conversion discovered in a small number of cases Often in p…
06 Oct 2015 Social Enbrels patent (2029) being challenged by Sandoz's etanercept biosimilar recently filed w/ the FDA http://t.co/73CDlh4l05
22 Feb 2016 Social Emery & colleagues plan to study rapidity/depth of remission of VERY early Enbrel (@1st visit) in early RA (VEDERA) https://t.co/UsoUlt9PoH
23 Mar 2016 Social Real life H2H comparison 295 Humira & 84 Infliximab Rx Crohns showed non-significant equal failure rates (21 vs 25%) https://t.co/okUyyCE4nL
18 Oct 2016 Social TNF inhibitor use in 16 renal transplant pts w/ good efficacy, no decline in GFR x2yrs, but 1/2 had Serious infxns https://t.co/2UHyaiVOpM