Friday, 15 Nov 2019

TNF inhibitor

Date Typesort ascending Title Save
23 Mar 2016 Social Real life H2H comparison 295 Humira & 84 Infliximab Rx Crohns showed non-significant equal failure rates (21 vs 25%) https://t.co/okUyyCE4nL
02 Apr 2017 Social Abbvie announces that Humira is now FDA approved for use in severe finger nail psoriasis. https://t.co/hRkbtCqWPn
31 May 2016 Social Recurrent acute anterior uveitis responds to golimumab 50 mg qmo; 12/15 eyes from B27+ AS pts going into remission https://t.co/0ttwTe56zv
06 Nov 2017 Social RT @japaoli19: Crib study shows no detectable levels of CZP on infants umbilical cords #ACR17 @RheumNow https://t.co/7C1ctxv76c
09 Jul 2015 Social 1964 Turkish pts Rx w/ TNF inhibitors- TB rate of 466/100,000. TB risk greatest w/ Behcets; lower if PPD >10mm http://t.co/rWJIBKA3MO
18 Oct 2016 Social TNF inhibitor use in 16 renal transplant pts w/ good efficacy, no decline in GFR x2yrs, but 1/2 had Serious infxns https://t.co/2UHyaiVOpM
13 Feb 2016 Social FDA arthritis advisory votes 21-3 in favor of approving the Celltrion CT-P13 (Inflectra) a biosimilar of infliximab https://t.co/P6R75QOB7j
03 Mar 2017 Social RT @USBiosimilars: #AAD2017 Surveyed physicians lack understanding of interchangeability. #Biosimilars Forum has info on this concept. http…
07 Apr 2016 Social Theres a new Biosimilar in the US called inflectra - some of the early talking points and issues covered @ RheumNow https://t.co/21JQlfxxY9
12 Jan 2018 Social 188 PsA pts receive 1st TNFi, 27% D/C by 24 mos (1/3 for primary inefficacy, 22% secondary inefficacy, 43% adverse events) Predictors of failure = female or metabolic syndrome-co-morbidities (HR = 2.65). https://t.co/VRdikUSQ0f
30 Aug 2016 Social Drug retention rates are same between elderly and younger RA pts on TNFi. D/C for AE in old and efficacy in young. https://t.co/ZPXlXvVpTS
21 Nov 2016 Social Retrosp study of Humira in 40 pts (66 eyes) w/ Behcets ocular dz showed signif less flares (200-->8.5/100PY) w/ ADA https://t.co/t8ldrYptGD
21 Nov 2015 Social Do patients on TNF inhibitors become "born again"? well enough to go bungee jumping and join the marines! https://t.co/e08St1MaIJ
24 Mar 2017 Social Amgens Amjevita (biosimilar of Humira) was approved by EMA for EU use in adult/Peds arthritis IBD, SpA & more https://t.co/O7JBrvtZgE
26 May 2016 Social TNF inhibitors & Traveling? 1 infusion or injection OK a Wk early or late 2 Forget the dry ice, keep syringe cool n dry (eg purse) on plane
04 Nov 2017 Social RT @psufka: @_connectedcare My approach: If primary nonresponse to TNFi -> IL-17. If secondary nonresponse to TNFi -> 2nd TNFi #ACR17
08 Jul 2015 Social TNF inhib use causes steatohepatitis? VA report 8 pts shows TNFi, MTX & PNPLA3 gene mutations may be risks for NAFLD http://t.co/HuxmtZsU62
20 Feb 2018 Social PANTS study:Personalized anti-TNF Therapy in Crohn Disease tests real-world eficacy, safety & immunogenicity of infliximab vs biosimilar CT- P13 vs adalimumab. Wk 54 remission rate was 40% INFX, 40% CTP13 & 34% in ADA; immunogenicity was 26%, 28%, 11% https://t.co/irhImH6ipP
06 Oct 2016 Social IRAK3 rs11541076 polymorphism yields 33% increase odds of response to TNFi. NLRP3 rs461266 has 25% fewer responses. https://t.co/qIuf7dJKU3
17 Feb 2017 Social RT @DrRachelTate: Biosimilars - noninferior in switch trial from IFX and CT-P13 @RheumNow @RWCSmtg https://t.co/bBAaUWHGt1