Tuesday, 07 Apr 2020

TNF inhibitor

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03 Mar 2017 Social RT @USBiosimilars: #AAD2017 Surveyed physicians lack understanding of interchangeability. #Biosimilars Forum has info on this concept. http…
07 Apr 2016 Social Theres a new Biosimilar in the US called inflectra - some of the early talking points and issues covered @ RheumNow https://t.co/21JQlfxxY9
17 Feb 2020 Social Slovenian National TB Registry (a non-endemic area w/ TB rate 6/100k similar to US). 2429 TNFi exposed (RA, AS, PsA)-6% required TB chemoprophylaxis; 6 RA and 2 PsA developed TB; 2 pts died. The TB incidence rate for TNF Rx pop was 45-51/100kPYs https://t.co/tam5I17QO1
04 Nov 2017 Social RT @psufka: @_connectedcare My approach: If primary nonresponse to TNFi -> IL-17. If secondary nonresponse to TNFi -> 2nd TNFi #ACR17
06 Oct 2016 Social IRAK3 rs11541076 polymorphism yields 33% increase odds of response to TNFi. NLRP3 rs461266 has 25% fewer responses. https://t.co/qIuf7dJKU3
21 Nov 2015 Social Do patients on TNF inhibitors become "born again"? well enough to go bungee jumping and join the marines! https://t.co/e08St1MaIJ
20 Feb 2018 Social PANTS study:Personalized anti-TNF Therapy in Crohn Disease tests real-world eficacy, safety & immunogenicity of infliximab vs biosimilar CT- P13 vs adalimumab. Wk 54 remission rate was 40% INFX, 40% CTP13 & 34% in ADA; immunogenicity was 26%, 28%, 11% https://t.co/irhImH6ipP
24 Mar 2017 Social Amgens Amjevita (biosimilar of Humira) was approved by EMA for EU use in adult/Peds arthritis IBD, SpA & more https://t.co/O7JBrvtZgE
26 May 2016 Social TNF inhibitors & Traveling? 1 infusion or injection OK a Wk early or late 2 Forget the dry ice, keep syringe cool n dry (eg purse) on plane
25 Nov 2019 Social VERVE results - Live zoster vaccine safe and effective in >600 patients with autoimmune diseases treated wth TNFi abstr#0824 #ACR19 @CCalabreseDO https://t.co/F8ipuG08O3
08 Jul 2015 Social TNF inhib use causes steatohepatitis? VA report 8 pts shows TNFi, MTX & PNPLA3 gene mutations may be risks for NAFLD http://t.co/HuxmtZsU62
06 Sep 2015 Social 2013 global sales: ETN $11.1 bill, INFL 9.9 bill, ADA 8.9 bill. RA sales increase from $56B in 2013 to $80B in 2020 http://t.co/2zWeVhP3XF
17 Feb 2017 Social RT @DrRachelTate: Biosimilars - noninferior in switch trial from IFX and CT-P13 @RheumNow @RWCSmtg https://t.co/bBAaUWHGt1
31 Mar 2016 Social Infliximab rarely gives incr LFTs. 305 IBD pts sudied &shows that LFT elevations more likely from DMARDs than INFLX https://t.co/rfPK6bVXF2
08 Aug 2016 Slide of the day Tuberculosis Risk Reduction Measures
29 Feb 2016 Slide of the day How to manage TNFi during surgery
29 Aug 2016 Slide of the day Non-Tuberculous Mycobacterial Infection are Common with TNF Inhibitors
24 Jul 2019 Slide of the day anti-TNF Biosimilars in USA
09 Dec 2019 Slide of the day Even More Biosimilars
28 Oct 2019 Slide of the day New Biosimilars for Rheumatology - 2019