Friday, 23 Aug 2019

TNF inhibitor

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06 Nov 2017 Social RT @uptoTate: Anti-TNF drugs could be safe following paternal exposure in pregnancy outcomes. #ACR17 @RheumNow #1312 https://t.co/G4s9zyOhoY
24 Mar 2016 Social 1st TNFi H2H results are in: EXXELERATE study Cimzia vs Humira shows equal ACR20 @3mo (69 v 71%) & LDAS @2y(35 v 33) https://t.co/qvcQdnAlxy
09 Jun 2016 Social Do all TNFi work the same way? J Exp Med article suggests unique Humira MOA, expanding functional Foxp3+ Treg cells https://t.co/2zf6u8Q39J
20 May 2015 Social TNFi Rx RA patients who also took MTX, had a significantly lower risk (64% less) for future large joint replacement. http://t.co/CQ211se7je
09 May 2019 Social Analysis of claims data compared hospitalized infection rates among 11,248 matched pairs of new initiators of abatacept or TNF inhibitors. Serious hosp infections were significantly lower in ABA vs infliximab (HR 0.63; 0.47-0.85), but similar to ETN & ADA https://t.co/JhXlC7p1A7
24 Jan 2017 Social Janssen has applied to FDA for new indications (AS, PsA) for golimumab based on GO-ALIVE, GO-VIBRANT trials https://t.co/qTZMJtWmya
14 Jul 2015 Social ESPGHAN cautions on biosimilar use; studies on safety & immunogenicity should be mandatory in children w/ IBD http://t.co/Gpa6HmP2U5
22 Apr 2017 Social FDA approves another infliximab biosimilar - Renflexis (Infliximab-abda) from Bioepis, distributed in US by Merck. https://t.co/r74qr73XaI
18 Apr 2016 Social Celltrion chief executive said that Inflectra expected to be priced ~20-30% lower than Remicade in the US. https://t.co/ceCHuYubzK
25 Oct 2018 Social RT @NicoleBitencou5: Use of antiTNF in childhood does NOT appear to increase risk of malignancy in adults according to Medicare claims data…
01 Dec 2016 Social Good overview TB risk on TNFi (0.79%), all tx & recovered but 1 death. 76% restarted TNFi with only 1.3% TB recurr https://t.co/DQbeFmWmLX
04 Mar 2017 Social RT @ACRheum: #Biosimilars: What Do Patients Need to Know? Read the Q&A blog post from @AngusWorthing & @ACRSimpleTasks → https://t.co/GP9wC…
15 Sep 2015 Social Health Canada is reviewing few reports of schizophrenia & psychiatric dz associated with Enbrel use. http://t.co/pAFr2CSE1k
22 May 2017 Social Survey of 364 UK RA pts shows that giving info on TNFi helps 1/3 and scares 1/3. Many misconceptions about safety https://t.co/lM8gxjjulk
16 Feb 2016 Social Infliximab induced skin manifestations (23%) includes eczema and psoriasis like lesions - 41% were exacerbations https://t.co/8V9T2tyIL4
31 May 2016 Social Samsung Bioepis Flixabi (a Remicade biosimilar) approved for all 6 indications in 28 EU states & Norway, Iceland. https://t.co/oHwkbozHSG
14 May 2015 Social RheumNow: Major liver toxicity is rare with TNF inhibitors, minor LFTs are common. http://t.co/bJAmMFxJvq
04 Jan 2017 Social TNF inhibitor survival in 2687 Finnish pts - 27% discontinue TNFi in 12 mos. Worse w/ CZP & Rem, better w/ combo MTX https://t.co/13vJxWGWCs
24 Mar 2017 Social RT @DanielHSolomon: MI Risk 39% Lower for Patients With RA Taking TNF Inhibitors https://t.co/7ihHmdNPNy via @medscape
30 Nov 2015 Social Amgen submits BLA application to the FDA for their version of adalimumab/HUMIRA (ABP 501) biosimilar https://t.co/KRjewSNeqf