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ICYMI: Preventing COVID - Masks, Meters and Eyewear

Jul 09, 2020

A Lancet systematic review and meta-analysis provides the basis for physical distancing and the value of making as measures to prevent infection with coronavirus 2 (SARS-CoV-2) or COVID-19. The analysis included 172 observational studies, no randomised controlled trials and 44 relevant comparative studies involving 25 697 patients. 

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H2H UPA vs ABA RCT; UPA is clinically superior to ABA in DAS-CRP remission, ACR50, ACR70 at wk 12/24 (NOT diff in P… https://t.co/7lwVCSYjPu

Dr. John Cush @RheumNow (  View Tweet)

Jul 09, 2020
Avacopan is as effective as steroids in ANCA Assoc Vasculitis – 330 pt RCT AAV Rx w/ RTX or CTX but randomized to p… https://t.co/mxm5NAjZtL

Dr. John Cush @RheumNow (  View Tweet)

Jul 09, 2020
#EULAR2020 #op0201 nationwide cohort study: higher incidence of dementia in SLE (3.9/1000pys) vs non-SLE ( 2.73/1000pys). HR 1.43. SLE risk of Alzheimer’s 1.4x &risk of vascular dementia 1.6x Higher than non-SLE cohort.

Dr. John Cush @RheumNow (  View Tweet)

Jul 09, 2020

ICYMI: COVID-19 and Thrombotic Complications

Jul 08, 2020

Severe and fatal outcomes with coronavirus infection are often the result of the downstream damage that follows the viral infection. Rising high on the list of complications are the hematologic and vascular complications seen in severely affected patients, so much so that many centers are routinely anticoagulating hospitalized (but not ambulatory) COVID patients.

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AHRQ estimates that 40-80% of information a patient is told during an office visit is forgotten immediately, and that almost half of the information a patient does retain is actually incorrect https://t.co/XeGx2YXsOQ

Dr. John Cush @RheumNow (  View Tweet)

Jul 08, 2020
23 yoF with 1 mos digital ulcers, hair loss, sicca Sxs, dysphagia; No sclerodactyly but finger tips cyanotic w/ distal pitting scars, ischemic ulcers, periungual erythema & dilated nailfold capillaries (no hemorrhages). +tests for ANA, Ro52, Ro60 and Scl-70 Abs. How to treat?

Dr. John Cush @RheumNow (  View Tweet)

Jul 08, 2020
African-Americans with Ank Spondylitis have worse disease compared to whites. Study of 10,990 AS patients shows AA to have high frequency of anterior uveitis, hypertension, diabetes, depression, and heart disease and higher ESR and CRP levels.

Dr. John Cush @RheumNow (  View Tweet)

Jul 08, 2020

ICYMI: The Nine Lives of Hydroxychloroquine (Updated)

Jul 07, 2020

Hydroxychloroquine is one of many medications frequently used in rheumatology practice. Its remarkable versatility is attested by its routine use in lupus, in patients with an autoimmune coagulopathy, in patients with rheumatoid arthritis, as well as in those with a low-level inflammatory arthropathy.

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Rheumatology Round-Up from #EULAR2020 w/ Drs. Kavanaugh & Cush.

Dr. John Cush @RheumNow (  View Tweet)

Jul 07, 2020
#EULAR2020 #op0106 Cosentyx 150mg demonstrates clinical improvement in NrAxSpA Sx in Ph3 PREVENT @52wk. Significant improvement in ASAS40, BASDAI50& ASdAS-CRP ID.
Dr. John Cush @RheumNow (  View Tweet)
Jul 07, 2020
CDC guidelines for Rx of Latent Tuberculosis; Preferred: A) 3 months of once-weekly INH plus rifapentine (3HP); B) 4 months of daily rifampin (4R); C) 3 months of daily INH plus rifampin (3HR) - Shorter, safer, effective with higher completion rates.

Dr. John Cush @RheumNow (  View Tweet)

Jul 07, 2020

ICYMI: Outcomes of Critically-Ill COVID Patients in NYC

Jul 06, 2020

Lancet has reported COVID outcomes from NewYork-Presbyterian hospitals in NYC during March 2020 showing high rates of hospitalization, ICU admission, mechanical ventilation and death.  A prospective observational cohort study 2 2 NYC hospitals from March 2 to April 1, 2020, looking at laboratory-confirmed COVID-19 and were critically ill with acute hypoxaemic respiratory failure, and collected clinical, biomarker, and treatment data. The

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A msg from my nurse friend: “A blood clot from my pt yesterday. Covid lungs. I helped changed his code to DNR, talked to his son/ex wife/brother&sister to say goodbye. He asked if I would pray w/him. I prayed. He cried. Then I walked out & lost it.
k dao @KDAO2011 (  View Tweet)
Jul 06, 2020
Case Controlled Study of 482 RA patients with ILD vs 741 RA w/o IL found an inverse relationship Between MTX exposu… https://t.co/ljtaKO8pVZ

Dr. John Cush @RheumNow (  View Tweet)

Jul 06, 2020
Rheumatologist Question: early on, what do you tell your RA patient their chance of future drug free remission?

Dr. John Cush @RheumNow (  View Tweet)

Jul 06, 2020
Pleased to share our work detailing events around HCQ and COVID-19. Started through texts with @alhkim about the news cycle being a swinging pendulum. The figure tells it all. Proud to work with @rheum_covid.

Jeff Sparks @jeffsparks (  View Tweet)

Jul 06, 2020
Rheumatoid Arthritis: Pathogenesis, Prediction and Prevention – An Emerging Paradigm Shift https://t.co/uNDsLmgaN7 #RA #prevention #Rituximab - nice article, still think if repeated Ritux to eliminate pathogenic abs would significantly prevent RA

Peter Nash @drpnash (  View Tweet)

Jul 06, 2020

RheumNow Podcast – Gout Guidelines (7.3.20)

Jul 03, 2020

Dr Jack Cush reviews the journal reports and news from RheumNow this past week. Highlights include:

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