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Infection or Disease Flare: What Tools Can Help Differentiate?
Differentiation between a flare of disease and infection in patients with autoinflammatory (AI) conditions, where fever is the hallmark, can be extremely difficult. Few studies have evaluated potential differentiators; and having such tools would meet a huge unmet need.
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Way to go Texas!
#ACRknowledgebowl winners #GullsofGalveston when they answered the final jeopardy round: This monogenic dz can mimic Behcet’s syndrome and occurs due to mutation in TNFAIP3 @utmbhealth #ACR21 @rheumnow
...What is ...Haploinsufficiency A20? https://t.co/ExjKqtykVy
TheDaoIndex KDAO2011 ( View Tweet)
Dr Sherbini @james_gwinnutt @khyrich on baseline factors associated with nausea and alopecia with MTX. Alcohol use (modifiable!) and 👩 assoc with both. Disease activity with nausea. HAQ with alopecia. Abstr#1444 #ACR21 @RheumNow #ACRBest https://t.co/e0BG9omnEv
Richard Conway RichardPAConway ( View Tweet)
axSpA and Depression
71 axSpA patients surveyed
Abnormal HADs-D scores ▶️Significantly worse BASDAI and AQoL scores
Severe PHQ-9 scores ▶️worse BASDAI, BASFI and ASQoL
Abst# 1305 #ACR21 @RheumNow https://t.co/Sf2Rm6z7ln
swethaann23 swethaann23 ( View Tweet)
#ACR21 Ab#1444 @AhmadSherbini. Factors ass w/ nausea & alopecia in MTX
⭐️Nausea & alopecia: ♀️, 🥃, activity score are risk factors
▶️EtOH highlights importance of folic acid in these pts!
@Rheumnow https://t.co/6UNUVh5ZW8 https://t.co/lxB2z2lXtu
Links:
Eric Dein ericdeinmd ( View Tweet)
Rheumatology Research Foundation Lecture: Learning lessons from @Google to harness #omics to better understand #RA
#ACR21 @RheumNow @RheumResearch https://t.co/NVAe2Rqo1O
Mrinalini Dey DrMiniDey ( View Tweet)
Love-hate relationship with #methotrexate. Side effects are common ex nausea/GI in 1/3 and alopecia in women. ?if you ask do you get more AES. Tough to treat especially SEs are early. ?Coach pt to help w persistence abst1444# @RheumNow #ACR21 https://t.co/NDQDVz8lk2
Janet Pope Janetbirdope ( View Tweet)
Dr Stewart @TonyMerriman2 report in 16,000 patients that repeat serum urate testing not superior to single measure in predicting incident gout over 9 years. Makes sense in general, maybe different in those with medication changes etc? Abstr#1449 #ACR21 @RheumNow https://t.co/69NofMNuB8
Richard Conway RichardPAConway ( View Tweet)
@NamrataRheum on outcomes in RA patients on RTX who get COVID-19. ⬆️hospitalisation, ICU, mech ventilation, but not mortality (in this cohort) Abstr#1445 #ACR21 @RheumNow https://t.co/8RcrzTdEb0
Richard Conway RichardPAConway ( View Tweet)
Guselkumab treatment of PsA improved Hgb levels and ⬇️ incidence of anemia
⭐️Anemia resolution associated with improved clinical status
#ACR21
#ACRBest
Abs#1331
@RheumNow
https://t.co/nbG7DpMDaR https://t.co/rxWsVfNqed
Robert B Chao, MD doctorRBC ( View Tweet)
#Uveitis is the most ⬆ freq xtra-articular manifestation in axSpA.
What factors are assoc'd w/AAU attacks?
👁🗨Active disease
👁🗨History of AAU
Bottomline: Treat axSpA, treat uveitis = better outcomes.
@RheumNow #ACR21 abs1314 https://t.co/O0kHulwJoP
sheila RHEUMarampa ( View Tweet)
#ACR21 Ab#1445. RTX & #covid19 outcomes
⭐️RTX ass. w/ ⬆️ COVID hospitalization, ICU admission, and ventilation
▶️ We need huge caution in pts that have not been vax'ed before RTX 💉💉
@Rheumnow https://t.co/6UNUVh5ZW8 https://t.co/R7jNb066m6
Links:
Eric Dein ericdeinmd ( View Tweet)
Yup, another large database shows more #hospitalizations with #RheumatoidArthritis with #rituximab but NOT higher mortality in matched analysis. Abst#1445 #ACR21 @RheumNow https://t.co/9XV8iX10sA
Janet Pope Janetbirdope ( View Tweet)
axSpA and Uveitis
Uveitis
🔼 in HLA-B27; Disease duration; Latin American pts
🔽 in Psoriasis
⭐️Uveitis was not significantly different in axSpA vs pSpA
Recurrent Uveitis
🔼disease duration and body mass index (BMI)
Abst #1307 #ACR21 @Rheumnow https://t.co/QDg8tOPgir
swethaann23 swethaann23 ( View Tweet)
Rheumatologists and Health Professionals: Join us tonight for RheumNow's #ACR21 Daily Recap at 7pm Eastern time . Register via the Zoom link below.
https://t.co/LLCt4wk1zj
Or visit our YouTube channel-RheumNow.
https://t.co/7S0YgJKPga https://t.co/pkmI8cLxni
Dr. John Cush RheumNow ( View Tweet)
Knowledge Bowl at #ACR21
⭐️Increased susceptibility to a certain most common adult vasculitis is conferred by this HLA allele
➡️HLA DRB10404
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Knowledge Bowl at #ACR21
⭐️The first lung fibrosis described in Sjogren's with lung biopsy showing benign polyclonal lymphocytes and plasma cells with a risk for malignant transformation.
➡️Lymphocytic Interstitial Pneumonia
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Get to know your program officer!
Plan in advance!
Attention to detail!
Key takeaways from the NIH Q and A #ACR21 @ashira_md @RheumNow
Bella Mehta bella_mehta ( View Tweet)
You know you made it when you name appears on #ACRknowledgebowl @RheumNow #ACR21 on a question about who deveoped criteria for #AOSD https://t.co/VR5NQOfS3r
TheDaoIndex KDAO2011 ( View Tweet)
Emerging Therapies in Spondyloarthritis: A Promising Pipeline by Dr. Olga Petryna (@DrPetryna ) #ACR21
https://t.co/9ggUAh0YJe https://t.co/WHpQp3GYBe
Links:
Dr. John Cush RheumNow ( View Tweet)