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Knowledge Bowl at #ACR21
⭐️This HLA allele confers a risk for a severe psoriasis phenotype, typically guttate type.
➡️HLA Cw6
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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Abst1344 #ACR21 @RheumNow observational study of pts w/PsA treated w/b&tsDMARD:pts who achieve MDA (22.8% of pts at 6 mo) more likely to maintain the initiated bDMARD or tsDMARD Rx & less likely to switch from the initiated bDMARD/tsDMARD https://t.co/egFDHV3eQs
Olga Petryna DrPetryna ( View Tweet)
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#ACRknowledge bowl question asks the 5 D’s of Charcot joint, but really there are 6. #ACR21 @rheumnow.
1. Distended
2. Disorganized
3. Dislocated
4. Debris (intraarticular bodies, which can be seen with synovial osteochondramotosis)
5. Density increased (sclerosis)
6. Destruction https://t.co/g0YsIFsEtv
TheDaoIndex KDAO2011 ( View Tweet)
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#ACR21 Abs#1367.
Scleroderma pts with absent contractility (AC) associated with diffuse cutaneous disease, cardiac involvement, more severe Raynaud's.
⭐️14/67 AC pts died during study (21%), none without AC
⭐️15/16 Ro52+ pts had AC (p=0.06)
https://t.co/GAuOiV5ScC @Rheumnow
Links:
Eric Dein ericdeinmd ( View Tweet)
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Knowledge Bowl at #ACR21
⭐️In this triad seen in TB arthritis, one can see juxta-articular osteopenia, peripheral osseous erosions, and late joint space narrowing
➡️Phermister's triad
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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#volcosporin good ~lupus nephritis added to #MMF but underbelly - side effects like but ?less than #cyclosporin. #FDA update - ⬆️hypertension and nephrotoxicity, infection #ACR21 @RheumNow https://t.co/w5nLLSTlrB
Janet Pope Janetbirdope ( View Tweet)
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Knowledge Bowl at #ACR21
⭐️Which HLA allele confers an increased risk for anterior uveitis and inflammatory sacroillitis?
➡️HLA-B27
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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BAFF & APRIL support B cell development, diff, survival.
ALPN-303: Antagonist of both BAFF & APRIL
💠⬇️B cell fxn & Ab production,⬇️Plasma cells
💠⬇️UProt, dsDNA, renal immune complexes (mouse model)
💠Pending human studies
https://t.co/kzVpUDuNWs
#ACR21 Abst#1429 @RheumNow
Pedro Castillo _Castillo_Pedro ( View Tweet)
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My summary article on some of the many abstracts at #ACR21 on #WorkParticipation in #axSpA.
Featured abstracts in this article:
#0358 https://t.co/LrZYWqCuOm
#0362 https://t.co/flL5MiqDL8
@RheumNow
https://t.co/tu5L0yIVIV
Links:
Mrinalini Dey DrMiniDey ( View Tweet)
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Are you using less #rituximab in #SLE during #COVID #ACR21 @RheumNow #Lupus hub
Janet Pope Janetbirdope ( View Tweet)
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#ACR21 Knowledge Bowl Final Question: Vasculitis Mimics: @RheumNow https://t.co/laD3oO8Uq9
Eric Dein ericdeinmd ( View Tweet)
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1st Place in #ACR21 #Rheum Knowledge Bowl Gulls of Galveston
Congrats to Daniel Gonzalez and Aparna Das!
@RheumNow @UTMBProvost @UTMBInternalMed https://t.co/nXjy0CD1uY https://t.co/fAUTE3V8lo
Akhil Sood MD AkhilSoodMD ( View Tweet)
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Knowledge Bowl at #ACR21
⭐️This disease featuring purple-red papulosquamous eruptions, on the hands and elsewhere, can have preceding painless erosive symmetrical arthritis at the DIPs, and has a 30% malignancy risk.
➡️Multicentric Reticulohistiocytosis
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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Top Influencers of #acr21: @ACRheum @rheum_cat @RheumNow @RichardPAConway @CreakyJoints @KDAO2011 @alhkim More 📊 https://t.co/vyMAwk1Mia
Symplur Hashtags healthhashtags ( View Tweet)
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Knowledge Bowl at #ACR21
⭐️This HLA allele can be seen in a certain vasculitis where panuveitis is a possibility and has a venulitis predilection
➡️HLA B51
@RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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If you need a #knee replacement move out of Ontario. More income disparity of access to #TKR in Ontario vs Pennsylvania. Lack of universal #healthcare in 🇨🇦. Oh Canada we fail. @RheumNow #ACR21 abst#1037 https://t.co/kobUlT3Ugr
Janet Pope Janetbirdope ( View Tweet)
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Novel way to treat inflammatory arthritis!
A bioengineered probiotic bacterium, L. reuteri (LrS235) was found effective to reduce inflammation and clinical signs of inflammation in rats with inflammatory arthritis.
Abst # 1707 #ACR21 @rheumnow https://t.co/UC28yRlGYP
TheDaoIndex KDAO2011 ( View Tweet)
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"Baseline and routine EKGS are NOT required for SLE patients just because they are on HCQ!" - Dr. HM Belmont. "The drug has been demonized due to its use in COVID patients. We don't need to hold HCQ for EMR alerts (e.g, with cipro, SSRIs, etc)." Abstr#1743 #ACR21 @rheumnow https://t.co/5Bxavo6dRg
TheDaoIndex KDAO2011 ( View Tweet)
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Wager question that cemented the winners: @UTMB:
⭐️This monogenic disease can mimic Behcet's & occurs d/t mutat in TNFAIP3.
➡️Haploinsufficiency A20
Congrats to the winners & all contestants, including the top 2 finalists: @MGHrheumatology & @EmoryUniversity!
#ACR21 @RheumNow https://t.co/LZqsBKiPL8
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
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Anti-NETs antibodies in #COVID.
1️⃣ correlate➖ w/ SpO2/FiO2 ratio (IgG r=-0.17 IgM r=-0.30
2️⃣correlate➕ w/ ⬆️D-dimer (IgG r=0.33 IgM r=0.19
3️⃣ ⬆️ in pts requiring MV
In a study of 328 pts. Probably driving complement activation!
#ACR21 #Abst1430 @RheumNow https://t.co/2MCrLueTzN
Aurelie Najm AurelieRheumo ( View Tweet)