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COLCORONA: Protective Effect of Colchicine in COVID-19

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d Jack Cush, MD

May 31, 2021

Lancet Respiratory Medicine has reported the results of the COLCORONA trial, showing that in patients with PCR-confirmed COVID-19 infection, colchicine led to a significantly lower rate of death or hospital admission from COVID.

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RheumNow Podcast – Heart, Lung & Liver (5.28.2021)

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d Jack Cush, MD

May 27, 2021

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

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News: EULAR Guidelines on Intraarticular Therapy EULAR has published evidence-based recommendations on the use of intra-articular therapies (IAT) based on the literature review and recommendations of a multidisciplinary international task force. https://t.co/Z6vC0x9zY1 https://t.co/gVCWMIJxtu

Links:

https://bit.ly/3covoo7

Dr. John Cush RheumNow ( View Tweet)

May 31, 2021

Study of National inpatient sample database (2015 to 2017) showed the frequency of atrial fibrillation in rheumatic disease (RD) pts finding that AF frequency highest in gout followed by vasculitis, and PMR. RD Mortality was 2 fold higher with AF. https://t.co/enno6hrKOI

Links:

https://bit.ly/2SHh4jx

Dr. John Cush RheumNow ( View Tweet)

May 31, 2021

A trial of sarilumab in 431 hospitalized COVID-19 patients on supplemental oxygen, Compared to placebo, sarilumab did not improve COVID outcomes https://t.co/postv1eK3F

Links:

https://bit.ly/34pRMsz

Dr. John Cush RheumNow ( View Tweet)

May 30, 2021

Kidney biopsies in patients with lupus – how early and how often? Dr. Fogo and Dr.Hogan explain why a kidney biopsy is critical for diagnosis and characterization of kidney involvement by SLE #SLEEducatorsNetwork. Sponsored by GSK US Medical Affairs https://t.co/ta3hliB9ls https://t.co/hJE6BNlNqk

Links:

https://bit.ly/34cs370

Dr. John Cush RheumNow ( View Tweet)

May 30, 2021

Pirfenidone, studied in 127 pts w/ CVD/CTD ILD, fibrotic interstitial pneumonia, chr hypersensitivity pneumonitis, & asbestoslung fibrosis. Pirefenidone had significantly less FVC% decline compared with placebo (p=0·043) https://t.co/H1s6ut4NhG

Links:

https://bit.ly/2RLVx9g

Dr. John Cush RheumNow ( View Tweet)

May 29, 2021

Dr. Samir V. Parikh from the #SLEEducatorsNetwork discusses the major treatment goals for lupus nephritis and the broader needs of the patient in this program- Defining Treatment Goals for Lupus Nephritis. Sponsored by GSK US Medical Affairs https://t.co/f2Y707H2kR https://t.co/4xMIBp2yEh

Links:

https://bit.ly/34d6qDD

Dr. John Cush RheumNow ( View Tweet)

May 29, 2021

RNL 2021: Treatment Advances in SpA: Dr. Nigil Haroon Dr. Nigil Haroon presents Treatment Advances in SpA at RheumNow Live 2021. https://t.co/9ZA0loThx6

Links:

https://bit.ly/3uu465G

Dr. John Cush RheumNow ( View Tweet)

May 29, 2021

News: Methotrexate Impairs COVID Vax Response https://t.co/M9d31UAxb7

Links:

https://bit.ly/3oVt6li

Dr. John Cush RheumNow ( View Tweet)

May 29, 2021

New podcast up! Download wherever podcasts are available. https://t.co/y95zS04pqw

Links:

https://bit.ly/3c10mSW

Dr. John Cush RheumNow ( View Tweet)

May 28, 2021

News: Efficacy of 6 Weeks Antibiotics with Prosthetic Joint Infections https://t.co/mSDEIKUL1h

Links:

https://bit.ly/34rZFOq

Dr. John Cush RheumNow ( View Tweet)

May 28, 2021

Danish registry study of 1,356 psoriasis and 370 PsA pts shows increased odd of coronary disease by CT Calcium scores - psoriasis w CACS ≥ 400 OR 1.25 (1.04-1.50); PsA CACS>0 OR 1.28 (1.00-1.64). Nearly a 49% incr risk in PSO (HR 1.49) https://t.co/jQSAV66TAi

Links:

https://bit.ly/3wFzTSW

Dr. John Cush RheumNow ( View Tweet)

May 28, 2021

Cross-sectional study RA and PFTs, shows among 2,008 cases, RA was assoc w/ increased odds of restrictive (OR 1.36) & obstructive patterns (OR 1.21) not explained by confounders like smoking. RA had lower predicted FEV1, FVC, FEV1/FVC https://t.co/cVxatLQCG4

Links:

https://bit.ly/34orrLK

Dr. John Cush RheumNow ( View Tweet)

May 28, 2021

Very cool article in Nature - Tissues, not blood, are where immune cells function https://t.co/NCBSBWhjTX

Links:

https://go.nature.com/3wErcYK

Dr. John Cush RheumNow ( View Tweet)

May 28, 2021

Meet the #SLEEducatorsNetwork in this disease education series where leading rheumatologists and nephrologists share their perspectives on lupus nephritis. Sponsored by GSK US Medical Affairs https://t.co/H9BqP9bW4i https://t.co/5AW1IRhBrC

Links:

https://bit.ly/3fNxoHh

Dr. John Cush RheumNow ( View Tweet)

May 28, 2021

RNL 2021: Best of times, worst of times (Keynote): Dr. Iain McInnes Dr. Iain McInnes presents his keynote lecture, Best of Times, Worst of Times..., at RheumNow Live 2021. https://t.co/v3hOYuJZad

Links:

https://bit.ly/3frZpUv

Dr. John Cush RheumNow ( View Tweet)

May 27, 2021

We'll be covering EULAR 2021 next week. Look for our coverage from June 3-8. https://t.co/YPNx8MBRn7

Dr. John Cush RheumNow ( View Tweet)

May 27, 2021

Unable to attend the Tuesday Night Rheumatology on RA and vaccines? Watch the replay below. https://t.co/hUFTjDAnsg https://t.co/ywCRjqg1To

Links:

https://bit.ly/3wHcLDx

Dr. John Cush RheumNow ( View Tweet)

May 27, 2021

Virtual DDW meeting this wk reports claims data comparing IBD to IBD with RA - IBD alone vs IBD w/ RA dx w/ more depression (21% vs 84%), anxiety (20% vs 47%). IBD w/ RA had more depression (OR 7.2); anxiety (OR, 1.25;) or both (OR, 2.3) https://t.co/B78xcJw584

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