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It's a Sore Subject
Cindy Chiu, DO, presents her poster at RWCS 2024.
https://t.co/Bl7mAL4grR https://t.co/9rLglObu4V
Dr. John Cush RheumNow ( View Tweet)
Mastery of knee arthrocentesis for internal medicine resident
Brian D. Jaros, MD, presents his poster at RWCS 2024.
https://t.co/xFoEGnj2QH https://t.co/DpW07jJTLf
Dr. John Cush RheumNow ( View Tweet)
Sinusitis Linked to 40% Heightened Risk of Rheumatic Disease
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EurekAlert!
The common inflammatory condition sinusitis is linked to a 40% heightened risk of a subsequent diagnosis of rheumatic disease, particularly in the 5 to 10 years preceding the start of symptoms, finds research published in the open access journal RMD Open.
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Australian study shows self-reported difficulties w/ ambulation (limited<=1 km) had a higher risk of hip and spinal fractures (32% to 219% more)/ Included 239 000 adults >45 yrs https://t.co/IWvKmPc2t8 https://t.co/CDYDzhMUoa
Dr. John Cush RheumNow ( View Tweet)
Congratulations to Drs. David Felson Tuhina Neogi of Boston University in being awarded a U19 5 yr grant to fund Novel Insights into Osteoarthritis, Pain and Function: The Multicenter Osteoarthritis (MOST) Study. https://t.co/fGU9Zk2ECs https://t.co/dtT0hu7aA1
Dr. John Cush RheumNow ( View Tweet)
Cochrane Review: How Good is Ultrasound Diagnosing GCA?
Is temporal artery ultrasound (US) equivalent or superior to the reference standard of temporal artery biopsy (TAB) when diagnosing giant cell arteritis (GCA)?
https://t.co/AcETp0TJBF https://t.co/eKVmaro7D0
Dr. John Cush RheumNow ( View Tweet)
BC, Canada study of 149,902 new rheumatology referrals showed 31% more referrals 2019–2020 (vs 2010–2011). New inflammatory arthritis increased (28% to 51%), delays decr by 22 days; but time to 1st DMARD in RA decreased by only 4 days (6%) to 62 days https://t.co/LEyWcI6ojn https://t.co/QdL8VP1C6q
Dr. John Cush RheumNow ( View Tweet)
2021 NHIS Survey data suggests the prevalence of immunosuppression in the USA is 6.6% (4.4% immunosuppressive Dz; 3.9% immunosuppressive meds; 1.8% both); higher in women 7.9% ages 60-69 (9.5%) & Alaskan/Native indian (8.4%) https://t.co/phFPRqpCbJ https://t.co/non7zpQVOL
Dr. John Cush RheumNow ( View Tweet)
FDA has issued new draft guidance on the "Use of Data Monitoring Committees in Clinical Trials", updating its 2006 guidance document. "..the DMC should have access to safety results as well as comparative efficacy results." https://t.co/F0vKOxCLq9 https://t.co/xBa4Q1ukqo https://t.co/KeBUsYIl6u
Links:
Dr. John Cush RheumNow ( View Tweet)
FDA has issued new draft guidance on the "Use of Data Monitoring Committees in Clinical Trials", updating its 2006 guidance document. "..the DMC should have access to safety results as well as comparative efficacy results." https://t.co/F0vKOxCLq9 https://t.co/xBa4Q1ukqo https://t.co/KeBUsYIl6u
Dr. John Cush RheumNow ( View Tweet)
Sarcoid arthritis (SA) seen in 19% of sarcoid pts. Metanalsysis of 49 articles (8574 pts) found Ankles most frequent (80%) followed by knees & wrists. Monoarthritis was uncommon (1%). Acute , 0-2, I2 55%). Acute SA (oligo & poly) was linked to E nodosum. https://t.co/j5toHlmyoA https://t.co/oC1yxvFHRJ
Dr. John Cush RheumNow ( View Tweet)
In 551 juvenile myositis pts, 36% had myositis assoc Abs (MAA); 13% had >1 MAA. MAA+ pts had more overlap dz (18 vs 6%, p<.001) & assoc w/ Raynauds (OR 2.44), ILD (OR 3.43), chronic Dz (OR 1.72), mortality (OR 3.76). # MAAs was assoc w/ mortality (OR 1.83) https://t.co/BXhasmel3Z
Dr. John Cush RheumNow ( View Tweet)
Study of 43 SSc patients w/ gangrene shows Smoking Hx ; positive-ACA, ANCA, APL Abs & high ESR were independent risk factors for digital gangrenes in SSc. Vasculitis and macrovascular disease may contribute to the progression of digital gangrene https://t.co/3DY2Hx19s0 https://t.co/BfXANmckwF
Dr. John Cush RheumNow ( View Tweet)
Could Weight-Loss Drug Improve Hip Replacement Outcomes?
The antidiabetic/weight-loss drug semaglutide either does or does not help patients undergoing THA avoid complications and other poor outcomes, according to 2 retrospective studies presented here.
https://t.co/bB2E4T2aiI https://t.co/EWVcQ01GuL
Dr. John Cush RheumNow ( View Tweet)
Board question/clinical pearl alert: Hairy Kidney Sign is an important indicator of Erdheim-Chester. Dr. @anisha_dua #RWCS24 @RheumNow @RWCSmtg - abnormal histiocytes now classified as malignancy - bone pain common presenting complaint - can see aorta, pleura, pericardium… https://t.co/XO5GXSNJZk https://t.co/gBn8Hii7F0
Dr. Rachel Tate uptoTate ( View Tweet)
Retrospective study of non–small cell lung cancer(NSCLC) pts Rx w/ immune checkpoint inhibitor finds that those who develop immune-related AE (irAEs) (n=803) have improved overall survival (23.7 vs 9.8 mos survival; P < .001) https://t.co/yiwJZJU10W https://t.co/fwFFlf7Q6L
Dr. John Cush RheumNow ( View Tweet)
Catastrophic APL has high mortality.. Use of triple Rx w pulse steroids, IV heparin and plasma exchange still only has 50% survival. #RWCS24 https://t.co/ycttHcpmjL
Dr. John Cush RheumNow ( View Tweet)
NJ leads on prior authorization legislation:
- Prior auth turnaround time is 24 hrs urgent requests
- Peer-to-peers for denials involves same specialty MD
- Transparency: companies have to share data on denials/reasons.
(29 states w/ active bills/reforms) https://t.co/pZlyW68DDL https://t.co/uc251qj2Gf
Dr. John Cush RheumNow ( View Tweet)
Full read overview of SJOGRENS SYNDROME, which can be Primary SS or Secondary (15% in SLE, 20% RA, & 30% systemic sclerosis). SS Organ involvement:
- CNS 2-17%
- Renal <=10%
- ILD 10-20%
-MSK 45-56%
https://t.co/RElOFfP2xr https://t.co/aJI041VCuE
Dr. John Cush RheumNow ( View Tweet)
JAMA Clinical Challenge - Recurrent Fever, Rash, and Shortness of Breath in a 69-Year-Old. Admited with fever, fatigue, rash, right periorbital swelling, SOB, Palpable purpural, Serositis previously - whats your diagnosis? https://t.co/j6aSGffpPv https://t.co/du6pEo74xp
Dr. John Cush RheumNow ( View Tweet)