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Consequence of aged immune system.
Connie Weyand.
#RNL2024
@RheumNow https://t.co/gfCTfzulR9
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Inflammation or Inflammaging? The aging immune system in the host predisposes the development of RA, Cornelia Weyand, #RNL2024 @RheumNow https://t.co/30Zbf8kRXs
Dr. Antoni Chan synovialjoints ( View Tweet)
Aging in RA: "(RA) is due to a poorly functioning immune system which increases a patients risk of CVD, infection, and cancer. The aging immune system additionally affects this process. We must consider this clinically, we must protect our aging patients without over… https://t.co/TlHyTxPMNc https://t.co/JBVg4uqn6A
Dr. Rachel Tate uptoTate ( View Tweet)
Aging in RA: "(RA) is due to a poorly functioning immune system which increases a patients risk of CVD, infection, and cancer. The aging immune system additionally affects this process. We must consider this clinically, we must protect our aging patients without over… https://t.co/TlHyTxPMNc https://t.co/JBVg4uqn6A
Dr. Rachel Tate uptoTate ( View Tweet)
#RNL2024 @RheumNow
As we age, we gain not just wisdom, but also "Inflammaging"
Immune system changes in our inflammatory cells lead to:
- Poor vaccine response
- High risks for infections
- High risk for CVD
- High risk for autoimmunity https://t.co/golMAPR0ZI
Eric Dein ericdeinmd ( View Tweet)
Useful resource on dietary guidance in RA from @ACRheum focusing on a MD-like diet #RNL2024 @RheumNow https://t.co/QplaQ1caxv.
Dr. Antoni Chan synovialjoints ( View Tweet)
Vit d and omega 3 reduces incidence of RA.
Hani El Gabalawy.
#RNL2024
@RheumNow https://t.co/BGGbLvMhhT
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Good number of ACPA positive patients reverts to ACPA negative in 5 years.
Hani El Gabalawy.
#RNL2024
@RheumNow https://t.co/yLxO0ulsam
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Dr. Kavanaugh: "Role of alcohol on inflammation? It's part of the Mediterranean diet!"
Dr. Guma:"The data is mixed; polyphenols may be beneficial; alcohol in limited quantities was allowed in studies"
Dr. Weber:" Be careful w/EtOH in pts w/palpitations"
#RNL2024 @rheumnow
TheDaoIndex KDAO2011 ( View Tweet)
Do you use the ASA24?
Dr. Gabalawy asked Dr. Guma about this index at the #RNL2024. These indices don't quite encompass all aspects of the ACR recommended Mediterranean diet, for example, but could be useful in developing better assessments for patients and their diet.… https://t.co/v4Fu43u7et https://t.co/CTV2IaJ1xW
Dr. Rachel Tate uptoTate ( View Tweet)
Do you use the ASA24?
Dr. Gabalawy asked Dr. Guma about this index at the #RNL2024. These indices don't quite encompass all aspects of the ACR recommended Mediterranean diet, for example, but could be useful in developing better assessments for patients and their diet.… https://t.co/v4Fu43u7et https://t.co/CTV2IaJ1xW
Dr. Rachel Tate uptoTate ( View Tweet)
Panel discussion online and in person on #rheumatoidarthritis #RNL2024 Dr. Weber discusses with Dr. Guma, Dr. Gabalawy and @rheumnow ways to assess CV risk in patients by looking at family history, inflammation, comorbidities, imaging studies https://t.co/yM58kvr7CR
TheDaoIndex KDAO2011 ( View Tweet)
How do you communicate risk/benefit to patients? @RADoctor's recent publication highlighted by Dr. H. Gabalawy at #RNL2024 @RheumNow
1. Increase awareness
2. Include numbers for context
3. Make it easy for patients to understand those numbers
4. Use absolute risks
5. Avoid 1 in… https://t.co/DqmgD2j5Wp https://t.co/v6CQAX9YRr
Dr. Rachel Tate uptoTate ( View Tweet)
How do you communicate risk/benefit to patients? @RADoctor's recent publication highlighted by Dr. H. Gabalawy at #RNL2024 @RheumNow
1. Increase awareness
2. Include numbers for context
3. Make it easy for patients to understand those numbers
4. Use absolute risks
5. Avoid 1 in… https://t.co/DqmgD2j5Wp https://t.co/v6CQAX9YRr
Dr. Rachel Tate uptoTate ( View Tweet)
Managing patients with clinically suspect arthritis (CSA), <20% of ACPA positive patients without arthralgia develop RA in 5 years, Hani El Gabalwy #RNL2024 @RheumNow https://t.co/RKaDsozhXl
Dr. Antoni Chan synovialjoints ( View Tweet)
Per this study: 40% of pts had RA at 5 years and 40% were seronegative at 5 years. (See red line box) Interesting finding from Dr. H. Gabalawy #RNL2024 @RheumNow https://t.co/m5zJkDO2bk
Dr. Rachel Tate uptoTate ( View Tweet)
“Less than 20% of low +CCP patients who are asymptomatic will develop RA over 5 years” – Dr. Gabalawy recommends lifestyle changes (STOP smoking, Mediterranean diet, exercise) ; a substantial proportion will revert to ACPA neg state #RNL2024 @RheumNow https://t.co/yyHwVZWOf0
TheDaoIndex KDAO2011 ( View Tweet)
Why should we care about preclinical RA? Goal: to treat once and stop the trajectory of the disease. – Dr. Gabalawy #RNL2024 @rheumnow https://t.co/afbpvrZV8v
TheDaoIndex KDAO2011 ( View Tweet)
<20% of anti-CCP+ pts without arthralgia with develop RA in 5 years!
Dr. H. Gabalawy
#RNL2024 @RheumNow https://t.co/OXe7EWfCmc
Dr. Rachel Tate uptoTate ( View Tweet)
Rheums are "all over the map" but tend to skew conservatively when treating pre-clinical RA.
Dr. H Gabalawy discusses the results of a case-driven polling question at #RNL2024 @RheumNow.
Be sure to register at https://t.co/DXQ0KCelIh to hear his, and other, lectures to weigh… https://t.co/Yo3ChNwNIO https://t.co/wD3AMUDNr9
Links:
Dr. Rachel Tate uptoTate ( View Tweet)