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    RT @doctorRBC: Deucravacitinib: TYK2 inhibitor in pts with active SLE
    Phase 2, randomized, double blind, placebo-control

    Robert B Chao, MD doctorRBC

    1 year 10 months ago
    Deucravacitinib: TYK2 inhibitor in pts with active SLE Phase 2, randomized, double blind, placebo-controlled study Met primary endpoint SRI response across all doses No death, MACE, VTE, systemic infections @RheumNow #EULAR2022 ABST#LB0004 https://t.co/yAM8qUZgee
    RT @doctorRBC: Sarilumab in pts with relapsing PMR - Phase 3 trial
    Sarilumab +14 week steroid taper - higher sustained R

    Robert B Chao, MD doctorRBC

    1 year 10 months ago
    Sarilumab in pts with relapsing PMR - Phase 3 trial Sarilumab +14 week steroid taper - higher sustained Remission than w/o sarilumab (28% vs 10%) Less flare occurrences Sarilumab noted to have higher incidences of neutropenia, arthralgia @RheumNow #EULAR2022 ABST#LB0006 https://t.co/SeetkBsYI3
    RT @synovialjoints: Witholding MTX after both doses or only after the second dose of ChAdOx1 vaccine yields higher antib

    Dr. Antoni Chan synovialjoints

    1 year 10 months ago
    Witholding MTX after both doses or only after the second dose of ChAdOx1 vaccine yields higher antibody repsonse compared to continuing MTX. Witholding MTX after second dose reduced the risk for flare. Data from MIVAC 1 and 2 #EULAR2022 @RheumNow LB https://t.co/GfL4eDXchb
    RT @synovialjoints: In bDMARD-naive patients with PsA, the 24 week efficacy and safety of BKZ in BE OPTIMAL LB0001 by Mc

    Dr. Antoni Chan synovialjoints

    1 year 10 months ago
    In bDMARD-naive patients with PsA, the 24 week efficacy and safety of BKZ in BE OPTIMAL LB0001 by McInnes et al. At Week 16 ACR50 44% BKZ, 10% PBO, ADA 46%. PASI 90 at Week 16, 62% BKZ, PBO 3%, ADA 41% and benefit continued to Week 24 #EULAR2022 @RheumNow https://t.co/LRZoxzM57J
    RT @doctorRBC: New biomarker for atherosclerosis, cardiovascular risk and disease activity in axSpA?
    Low Irisin associat

    Robert B Chao, MD doctorRBC

    1 year 10 months ago
    New biomarker for atherosclerosis, cardiovascular risk and disease activity in axSpA? Low Irisin associated with subclinical atherosclerosis, high CV risk and more severe disease activity in axSpA @RheumNow #EULAR2022 ABST#POS0327
    RT @RichardPAConway: Prof Hoi @alberta_hoi Anti-Sm in SLE. Present in 17%. Assoc severe disease activity, "classic" SLE

    Richard Conway RichardPAConway

    1 year 10 months ago
    Prof Hoi @alberta_hoi Anti-Sm in SLE. Present in 17%. Assoc severe disease activity, "classic" SLE manifestations, specific serologic and proteomic profile. Argues for Sm+ SLE being a specific subset (or even a "different" disease?) @RheumNow #EULAR2022 POS0774 https://t.co/a5dToAuao9
    RT @Janetbirdope: Sing an ARIAA! #Bestinclass Rx of arthralgia w +MRI showed delay of #rheumatoid arthritis w #Abatacept

    Janet Pope Janetbirdope

    1 year 10 months ago
    Sing an ARIAA! #Bestinclass Rx of arthralgia w +MRI showed delay of #rheumatoid arthritis w #Abatacept vs #placebo. NNT to prevent 1 RA [is 8 w Rx for 1 yr & then d/c-Yrs ago #MTX delayed onset of RA but benefit waned after d/c Rx. Both ?RA spectrum POS0531 @RheumNow #EULAR2022
    RT @doctorRBC: Bimekizumab: IL-17A and F inhibitor for tx of PsA - BE OPTIMAL trial reached primary endpoint: ACR50 44%

    Robert B Chao, MD doctorRBC

    1 year 10 months ago
    Bimekizumab: IL-17A and F inhibitor for tx of PsA - BE OPTIMAL trial reached primary endpoint: ACR50 44% vs. placebo Efficacy as early as 2 weeks No MACE, uveitis, IBD, deaths @RheumNow #EULAR2022 ABST#LB0001 https://t.co/sHRRwLlChi
    RT @drdavidliew: 72% of you would treat some high-risk subclinical arthralgias with MTX

    and Marta Mosca, in the #EULAR2

    David Liew drdavidliew

    1 year 10 months ago
    72% of you would treat some high-risk subclinical arthralgias with MTX and Marta Mosca, in the #EULAR2022 highlights, broadly agrees OP0070 Leiden data showed better function and presenteeism. And that’s a win in my book @RheumNow https://t.co/BqTLy4HBWR https://t.co/cwzJkH0f71
    RT @drdavidliew: Biosimilars and COVID vaccines have made nocebo more pertinent than ever.

    How do we combat it?
    First l

    David Liew drdavidliew

    1 year 10 months ago
    Biosimilars and COVID vaccines have made nocebo more pertinent than ever. How do we combat it? First line is good communication, and the foot soldiers are the right phrases. Language matters. #EULAR2022 @RheumNow https://t.co/U0Chv9ia1G
    RT @Yuz6Yusof: #OP0004 #EULAR2022 In line with EULAR President’s preech to go Digital, Prof Mosca highlighted a study

    Md Yuzaiful Md Yusof Yuz6Yusof

    1 year 10 months ago
    #OP0004 #EULAR2022 In line with EULAR President’s preech to go Digital, Prof Mosca highlighted a study which showed assessment of joints in RA could be done by taking photos and analysed their dorsal skin folds using convolutional neural network @RheumNow https://t.co/h03mieTcQt
    RT @drdavidliew: Post-ORAL Surveillance, the @eular_org RA treatment guidelines had to change.

    In the 2022 version:
    JAK

    David Liew drdavidliew

    1 year 10 months ago
    Post-ORAL Surveillance, the @eular_org RA treatment guidelines had to change. In the 2022 version: JAKi now separate sentence following bDMARDs, with proviso to mention risk. Sometimes guidelines have to tell us what we’ve all inevitably been expecting #EULAR2022 @RheumNow https://t.co/RPbPNi3vcW
    RT @ericdeinmd: #EULAR2022 POS0285
    130K UK patients had incident gout bw 2004-2020
    ⭐️Only 29% started on ULT w/in 12

    Eric Dein ericdeinmd

    1 year 10 months ago
    #EULAR2022 POS0285 130K UK patients had incident gout bw 2004-2020 ⭐️Only 29% started on ULT w/in 12 mos ⭐️Target urate level only 14% in 2004, only to 17% in 2020 Updated EULAR guidelines in 2016: No statistical difference in ULT Rx or target attainment @Rheumnow