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American College of OBs & GYNS and the Society for Maternal-Fetal Medicine both enthusiastically endorse COVID Vaccination of pregnant women, given the delta variant, low vax rates in Preg women and poor COVID outcomes in preg. https://t.co/AmP5eOEgr3
Links:
Dr. John Cush @RheumNow ( View Tweet )
2 years 7 months ago
Study of 265 students w/ a positive COVID-19 test looked at 378 close contacts. Infx rates w both persons masked -7.7%, but when unmasked-32.4% (aORs = 4.9;)
https://t.co/fYdH33JbWR
Dr. John Cush @RheumNow ( View Tweet )
2 years 7 months ago
Baricitinib & Tofacitinib are effective in COVID-19 pts. These drugs are expensive; baricitinib is $44/tablet, but much lower for generics worldwide. 14 day course of TOFA would be >$1,400 in the US (but $600 in France, $25 in India) https://t.co/r2cn1H2z8i
Links:
Dr. John Cush @RheumNow ( View Tweet )
2 years 7 months ago
MMWR reports that during the COVID Delta variant era, Vaccination against COVID-19:
- Reduces risk of COVID-19 infection 5X
- Reduces risk of COVID-19 Hospitalization >10X
- Reduces risk of COVID-19 DEATH 10X
https://t.co/rMRY84xX5F
Links:
Dr. John Cush @RheumNow ( View Tweet )
2 years 7 months ago
Probenecid, an OAT3 inhibitor, has inhibitory effects on RNA viruses (influenza, RSV) & decreases ACE2 expression. May have utility in COVID-19 as it was shown to inhibit SARS-CoV-2 replication in animal models https://t.co/MClSjpqpSa
Dr. John Cush @RheumNow ( View Tweet )
2 years 7 months ago
Differential Dx of immune-mediated necrotizing myopathies (IMNM) - HMGCR & Signal recognition particle Abs; checkpoint inhibitors, anti-Mi2 dermatomyositis, antisynthetase syndr. antimitochondrial Abs, GVHD, SARS-CoV-2 infection https://t.co/hhizx5gAet
Links:
Dr. John Cush @RheumNow ( View Tweet )
2 years 7 months ago
Analysis of records from the Mass General Brigham healthcare system in the Boston area, shows that breakthrough infections (after receiving SARS-CoV-2 vaccines) in patients with SARDs are not uncommon, and may be severe or fatal.
https://t.co/Ri5QipR7YY https://t.co/TaTFTKfAzm
Links:
Dr. John Cush @RheumNow ( View Tweet )
2 years 7 months ago
Confused by all the different types of #COVID 19 tests? They are broken down in an easy-to-use tool here: https://t.co/P5jHhnzFej #Antigen #Antibody #PCR @CreakyJoints @IFAiArthritis @US_Pain @IAFaccess @colorofcci @patientaccess @aimedalliance @patientsrising @AARDATweets
Lupus Association @LADAOrg ( View Tweet )
2 years 7 months ago
3 of 4 COVID hospitalized in NJ are unvaccinated.
- 5.6 mill fully Vax; 2.7 mill unvaccinated,
- COVID hosp. rate of 4.33/100,000 fully vaccinated & 26.33/100,000 for unvaccinated.
- Unvaccinated are nearly 6 times more likely to be COVID hospitalized
https://t.co/nvDNODBlRW https://t.co/h3CcLXGLXG
Links:
Dr. John Cush @RheumNow ( View Tweet )
2 years 7 months ago
Telephone survey of 278 Rheumatic Pts during COVID (July 2020) showed 22% reduced/interrupted treatments, only 11 (4%) stopped. Decisions made by half (49%). Stop Reasons: anxiety (48%), IV Rx access (45%), Rx unavailability (6.5%) https://t.co/XgJ1TJsHJG
Links:
Dr. John Cush @RheumNow ( View Tweet )
2 years 7 months ago
