NEJM: evolution of pyoderma gangrenosum skin lesions https://t.co/vsgQhsjY5q https://t.co/INrbTIc9kX
Links:
Dr. John Cush @RheumNow( View Tweet )
In 530 #GCA pts, relapses seen in 46%; but severe relapse (ischemi/aortic events) in 3%. Severe GCA relapse pts more likely to be younger at Dx(P=0.02), w/ more limb claudication(< 0.0001), fewer GCA-related cranial Sxs (<0.0001); but not higher mortality https://t.co/k7wgU6oMcn https://t.co/BKOfGmZ27u
Dr. John Cush @RheumNow( View Tweet )
Biomarker Predictors of Osteoarthritis
Science Advances has reported that Duke University researchers have validated a biomarkers of osteoarthritis that may be identified 2 years before the appearance of radiographic OA. S
https://t.co/z5Tg9pAgqO https://t.co/ltY4rEg9p3 https://t.co/AjCKaUW59X
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Dr. John Cush @RheumNow( View Tweet )
Full-read Overview of Macrophage Activation Syndrome - a rare complication of autoimmune inflammatory rheumatic dz; assoc w/ Still’s disease SLE, Kawasaki, dermatomyositis, RA, Sjögren’s. Precipitating factors, including genetics & infections reviewed https://t.co/LmL3BPmo6c https://t.co/OkfwpzNLAL
Dr. John Cush @RheumNow( View Tweet )
🏆Dr. Georg Schett's pioneering work in CAR-T for #autoimmune disease has landed him among the TIME100 Most Influential People in Health
“Not only are the patients in drug-free remission, but I believe many are cured of their autoimmune disease," he said
https://t.co/Rj7FpkluNg
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Healio Rheumatology @HealioRheum( View Tweet )
Articular Findings Sarcoidosis:
- Acute arthritis: Lg Jt Oligoarthritis; Loffgrens syndrome (hilar LN, arthritis, E. nodosum)
- Acute > Chronic arthritis
- Chronic arthritis: tenosynovitis, oligo- &polyarthritis, dactylitis, erosions or Jaccouds arthritis
Dr. John Cush @RheumNow( View Tweet )
Prospective look at 25 280 older adults (mean 74yrs) w/ incident fracture, shows impact of multimorbidity by Charlson Comorbid Index (CCI). If CCI =2-3, Incr risk of subseq Fx (16-25%) & death (HR ~2); If CCI=4+, Fx Risk ^33-48%, death HR~4. https://t.co/6wnhFNiSXH https://t.co/Xy2y0ANDRd
Dr. John Cush @RheumNow( View Tweet )
Prevalence of MSK presentations in practice = 21.1%, based on UK practice cohort. Most common: pain in LS spine (18%) & knee (17%). Re-presentations of existing Dx made up 74% all MSK consultations. Steroid injx given to 1/3 of knee consults https://t.co/nTioq1lCEB https://t.co/ecm8Kxz2cu
Dr. John Cush @RheumNow( View Tweet )
Chikungunya arthritis Metanalysis & good full-read review - 8 studies showing chronic arthritis (CCA) in minority of infected;, polyarticular, looks like RA, few seropositive, few w/ erosions on imaging. CCA may be progressive w/ irreversible damage https://t.co/Da7bKtM6oC https://t.co/OGBbIiGAc5
Dr. John Cush @RheumNow( View Tweet )
What a racket! Pharmacy benefit managers make billions collecting fees from payers & rebates from Pharma. 2022, these 3 (CVS Caremark, Express Scripts, OptumRx) control 79% of PBM market.Why is Congress dragging their feet here? Overview read from Reuters https://t.co/m5AnMFtEhf https://t.co/m5EwfcNMdo
Dr. John Cush @RheumNow( View Tweet )
Chikungunya arthritis Metanalysis & good full-read review - 8 studies showing chronic arthritis (CCA) in minority of infected;, polyarticular, looks like RA, few seropositive, few w/ erosions on imaging. CCA may be progressive w/ irreversible damage https://t.co/8NdBCGTfxF https://t.co/SLt5COmKVf
Dr. John Cush @RheumNow( View Tweet )
The lateral foot/ankle anatomy 🥰 https://t.co/yuGt1seUd4
Faraz Sethi @farazzledphysio( View Tweet )
Did you know the first clinical controlled trials were done on sailors with scurvy? They were randomized to: a quart of cider, HCl, 2 spoons of vinegar, pint of sea water, spicy nutmeg paste w/ water vs. 2 oranges and a lemon. Guess which sailors fared best? #RheumGR @UTSWRheum https://t.co/fAeCeIxZ9e
TheDaoIndex @KDAO2011( View Tweet )
#peritendinous #ultrasoundguidedinjection with #osteniltendon for Tendinopathy of the #tibialisposterior #tendon #mskus #pocus #pocushub #GElogiqE10r3 https://t.co/8qe1G27tAl
Dr Jörg Dünkel @SportklinikBern( View Tweet )
Biopsy Results in Sjogren's Syndrome Save
A prospective study from the Netherlands analyzed the comparative value of simultaneous labial and parotid salivary gland biopsies performed in patients with sicca complaints and suspected SjD.
https://t.co/meJgf7dI8N https://t.co/zHg6SgiufS
Dr. John Cush @RheumNow( View Tweet )
Best Imaging in Giant Cell Arteritis - US, PET, MRI?
Imaging is often instrumental in diagnosing and staging patients diagnosed with giant cell arteritis (GCA).
https://t.co/LXVB6cHDfO https://t.co/ArLNdEPuVx
Dr. John Cush @RheumNow( View Tweet )
Cross-sectional study of7887 NY & IL nurses: between 2018-21 top reasons for 2287 leaving nursing were planned retiring (39%), burnout (26%), insufficient staffing (21%), family obligations (18%) & COVID (17%)-- all addressable by health care employers https://t.co/Ls6p060mFB https://t.co/Pxpa8fqchz
Dr. John Cush @RheumNow( View Tweet )
We must consider this clinically, we must protect our aging patients without over immunosuppressing them." Dr. Weyand #RNL2024
Dr. John Cush @RheumNow( View Tweet )
RCT 302 Dupuytren contracture pts Rx w/ Surgery (n 101), needle fasciotomy (101), or collagenase injx (100). 292 & 284 completed; Success (>50% improved) @3 mos was same: 71%, 73% & 73%. @ 2 yrs, surgery was superior (78% vs. 50% or 65%) https://t.co/K74p1xpnZx https://t.co/xaC4pdPSFQ
Dr. John Cush @RheumNow( View Tweet )
JAMA: Industry Payments to Physicians ($12.13 billion 2013-22)
1 Ortho: $1,360,744,428
2 Neuro: $1,322,668,751
3 Cardio: $1,293,613,594
4 Heme/onc: $825,799,685
5 Int medicine: $588,249,423
6 Endo: $546,513,674
7 FP: $479,105,369
8 Rheum: $464,858,022
https://t.co/GCWchn9IMz https://t.co/6sRwOWm83y
Dr. John Cush @RheumNow( View Tweet )
CDC surveillance data 2019–2021 identified cases:
- 59,655 coccidioidomycosis
- 3,595 histoplasmosis
- 719 blastomycosis (unusually high fatality rate in 2021 of 17%; typically 8%–10%) https://t.co/cDC0nuZLsb https://t.co/Q4QkNtNvJc
Dr. John Cush @RheumNow( View Tweet )
7 Updates on Prosthetic Joint Infections
These are excerpts and takeaway summaries from several literature reports addressing the diagnosis and outcomes of prosthetic joint infections (PJI).
https://t.co/ulKvFBOeNx https://t.co/0rKNsvYZ14
Dr. John Cush @RheumNow( View Tweet )
Quote: ""I got the message. All of us get the message, sooner or later. If you get it before it's too late or before you're too old, you'll pull through all right." ~ Nat King Cole https://t.co/dtGqztmJie
Dr. John Cush @RheumNow( View Tweet )
Should all patients with #polymyalgia rheumatics be screened for #giantcellarteriitis with vascular #ultrasound? A recent viewpoint summarizes the evidence:
📊prevalence of subclinical GCA may be as high as 25%
https://t.co/UL6gWRdE5R https://t.co/EAlRyNNWYt
Links:
Annals of the Rheumatic Diseases @ARD_BMJ( View Tweet )
GEM: Dysphagia in myositis pts is from skeletal muscle involvement, causing upper pharyngeal dysphagia, but may also manifest as dysphonia, nasal regurgitation, or aspiration (w/ risk of pneumonia). https://t.co/MOyfdCJywC
Dr. John Cush @RheumNow( View Tweet )
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