CONTACT trial compared colchicine 0.5 mg tid vs naproxen 250 mg tid in treating 399 patients with acute #gout. Both drugs equally controlled patient pain, but colchicine had more diarrhea (46% vs 20%) and headache (20.5% vs 10.7%) in first 7 days. https://t.co/APVz98RcBO

• Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose…

RA pts have a high prevalence of osteoporosis (OP-34%) & vertebral osteoporotic Fx (VOPF-20%). OP risk with Older age, female sex, lower BMI, higher Dz activity & severity. VOPF risk driven by older age & higher GC daily dose. https://t.co/BbSmUHPrHf

• Prevalence and risk factors associated with vertebral osteoporotic fractures in…

NEJM: 77 yoF with Calcinosis & Systemic Sclerosis. 2-yr Hx of painful swelling of her fingertips. Skin findings of SSc, capillaroscopy shows dropout, disorganization & enlarged capillaries. Xrays showed calcifications - pt referred for surgical excision https://t.co/DKnTyp69eI

• http://bit.ly/2oNyrjR

Study of ANA+ people without lupus or CTD shows that fatigue does not increase odds of having lupus or CTD. 1/3 of ANA referrals had FM and fatigue was correlated with widespread pain. https://t.co/g8NqHzLngw

• Fatigue severity in anti-nuclear antibody-positive individuals does not correla…