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From BiTE to TriTE: Progress of T-cell Engagers in RMDs

The EULAR 2026 Congress in London showcased growing interest in T-cell engagers as a novel strategy to achieve deep B-cell depletion and drug-free remission in refractory rheumatic and musculoskeletal diseases (RMDs).

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Imaging in SpA: are we seeing a clearer picture?

As EULAR2026 comes to a close, practical learnings take precedence as clinicians head back to their clinics. Among them, the 2026 EULAR Update on Imaging Recommendations in SpA stands out.

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“Science is organized knowledge. Wisdom is organized life.” - Immanuel Kant

Dr. John Cush @RheumNow (  View Tweet)

NK Cells Without a CAR: AB-101 Is Neither CAR-T nor CAR-NK Much of the meeting came for the next CAR T readout. AB-101 drew attention for a different reason. It depletes B cells by a completely different route. https://t.co/8eZyDxL7wu https://t.co/Nvbj1NQb5A
Dr. John Cush @RheumNow (  View Tweet)
NEW FROM ACR: Clinical responses with an IL-23i in patients with active PsA See the efficacy and safety data through ~5 years in the RheumNow poster hall. Sponsored by AbbVie Medical Affairs + Health Impact. https://t.co/mT6WkG6Q6D https://t.co/nXZSaHj16m
Dr. John Cush @RheumNow (  View Tweet)
When Patients with RA Choose Their Treatment, Outcomes Are Better — Here's the Data Dr. Aurelie Najm discusses abstract OP0204 presented in London at the EULAR 2026 Congress. https://t.co/7mjclBgobB https://t.co/o9fuV5FRMv
Dr. John Cush @RheumNow (  View Tweet)
Obinutuzumab drives histologic remission in lupus nephritis At #EULAR2026, new data from the phase III REGENCY trial add to the case for obinutuzumab in lupus nephritis. Investigators report deep intrarenal B-cell depletion and significantly higher rates of histological https://t.co/13HY1qIDcj
Dr. John Cush @RheumNow (  View Tweet)
RA-ILD in the Age of Treat-to-Target: Put the Probe on the Chest RA inflammation may be under control, but RA-associated ILD remains a major challenge. At #EULAR2026, experts highlighted that ILD is one of the few RA outcomes not improving in the biologic era. Three new https://t.co/Qujhl3ktRp
Dr. John Cush @RheumNow (  View Tweet)
What’s New in Psoriatic Arthritis: A Whirlwind Tour At #EULAR2026, Prof. Dennis McGonagle highlighted three key PsA trends: the rise of single-cell and spatial transcriptomics, progress toward personalized care (though not yet fully realized), and the next frontier of defining https://t.co/zN4K92UnW9
Dr. John Cush @RheumNow (  View Tweet)
RA-ILD: Screening risk and genetic susceptibility Two abstracts presented at EULAR 2026 add important insights into identifying patients at risk for RA-ILD and understanding the genetic mechanisms that may underpin disease development. https://t.co/IABp8NhUtS https://t.co/j8UHK2GRd7
Dr. John Cush @RheumNow (  View Tweet)
Vasculitis Updates: Glucocorticoid use in AAV and GCA Vasculitis Updates: Glucocorticoids are the cornerstone of initial therapy for AAV and GCA—quickly reducing inflammation and preserving organs. EULAR has issued recommendations on glucocorticoid use in ANCA‑associated and https://t.co/hIOKyXDxyb
Dr. John Cush @RheumNow (  View Tweet)

How many CAR-T’s do we need to test drive?

CAR-T at #EULAR2026 raised as many questions as it answered. Here's what we know, what we're still asking, and why the answers matter.

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Low dose Blinatumomab: Many Relapse with an Unexpected Surprise Dr. Alfred Kim discusses abstract OP0203 presented at EULAR 2026 in London. https://t.co/ir9pdwBnH4 https://t.co/yjjgcA2TRv
Dr. John Cush @RheumNow (  View Tweet)
Renal Biopsies in SLE Dr. Andrea Fava reporting from EULAR 2026 in London. https://t.co/naCyEAutbb https://t.co/XgdiXY3hiO
Dr. John Cush @RheumNow (  View Tweet)
When Patients with RA Choose Their Treatment, Outcomes Are Better — Here's the Data Dr. Aurelie Najm discusses abstract OP0204 presented in London at the EULAR 2026 Congress. https://t.co/hHQFffTXH0 https://t.co/tXv0SnGBz1
Dr. John Cush @RheumNow (  View Tweet)
PsA Topic Panel: EULAR 2026 Join Drs. Jack Cush, Peter Nash, Antoni Chan, and Nelly Ziade for an expert discussion on the most important psoriatic arthritis developments emerging from EULAR 2026. Abstracts discuss: OP0187, OP069, LB0001, POS0668, OP071 https://t.co/S7Fz5YR3V0 https://t.co/treaJ1OzwB
Dr. John Cush @RheumNow (  View Tweet)
Obinutuzumab drives histologic remission in lupus nephritis At #EULAR2026, new data from the phase III REGENCY trial add to the case for obinutuzumab in lupus nephritis. Investigators report deep intrarenal B-cell depletion and significantly higher rates of histological https://t.co/AlJ5I8s2JE
Dr. John Cush @RheumNow (  View Tweet)
EULAR 2026 RA Topic Panel https://t.co/lLSL6FW9sg

Dr. John Cush @RheumNow (  View Tweet)

RA-ILD in the Age of Treat-to-Target: Put the Probe on the Chest RA inflammation may be under control, but RA-associated ILD remains a major challenge. At #EULAR2026, experts highlighted that ILD is one of the few RA outcomes not improving in the biologic era. Three new https://t.co/FXCKlyKYfr
Dr. John Cush @RheumNow (  View Tweet)
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