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Avacopan for ANCA Vasculitis Goes in Front of the FDA

MedPage Today
May 07, 2021

An FDA advisory panel will consider whether to recommend approval of an oral C5a inhibitor for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, with agency staff raising questions over the "clinical meaningfulness" of key study data.

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#LupusAwarenessMonth Dr. Janet Pope - Belimumab in SLE nephritis From ACR 2020 https://t.co/ZoMslbX5dF https://t.co/xnKXXRJ6wE
Dr. John Cush @RheumNow (  View Tweet)
May 07, 2021
#LupusAwarenessMonth Dr. Michelle Petri - Best Practices in Testing for Antiphospholipid Syndrome (LAC wins) From ACR 2020 https://t.co/IyeRDzw4BC https://t.co/nSkauHf29T
Dr. John Cush @RheumNow (  View Tweet)
May 07, 2021
New podcast alert! Falling or Falling in Love (5.7.2021) Dr Jack Cush reviews the best journal articles of the week from RheumNow https://t.co/HyAPN2rM3L https://t.co/C5XtqthO8I
Dr. John Cush @RheumNow (  View Tweet)
May 07, 2021
May is also arthritis awareness month! Why we love Rheumatology Fellows https://t.co/rNVjZZr9l4 #ArthritisAwarenessMonth

Dr. John Cush @RheumNow (  View Tweet)

May 07, 2021
News Feature: Drug Monitoring Ineffective with Infliximab Treatment A randomized trial compared TDM to no TDM in patients receiving infliximab for chronic IMIDs and found that TDM did not increase the odds of achieving remission. https://t.co/AVcX4EXY0l https://t.co/RlDij6ln61
Dr. John Cush @RheumNow (  View Tweet)
May 07, 2021
Falls are not uncommon in #RA patients; significant risk factors for falls include being elderly, un-married, higher pain scores, reported dizziness taking psychotropic medications and having lower HRQoL scores https://t.co/a8qA7n68q5

Dr. John Cush @RheumNow (  View Tweet)

May 07, 2021

Unique Oral Microbiome in Early and Pre-Clinical RA

May 06, 2021

An oral microbiome study of rheumatoid arthritis patients suggests that periodontal condition in patients with early rheumatoid arthritis and individuals at risk of RA.

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ARTIC REWIND - Don't Half DMARD Therapy

May 06, 2021

The ARTIC-REWIND study examined rheumatoid arthritis (RA) patients in remission on conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) to see if they could "step-down" their csDMARDs theray; but  the study showed that 25% those who went on half-dose experienced disease flares (less so in the stable-dose group).

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Today begins National Nurses week! God Bless Rheumatology Nurses https://t.co/JC9ExqnXEb #ArthritisAwarenessMonth https://t.co/bhuocIlHWT
Dr. John Cush @RheumNow (  View Tweet)
May 06, 2021
News Feature: Childhood Lupus May Hamper Adult Careers Long-term outcomes of kids with cSLE are uncommon, but this cSLE cohort analysis suggests that SLE significantly impacts their future education, vocation, and employment as they reach adulthood. https://t.co/RQc4JD3BIt https://t.co/l0ZQWHNFng
Dr. John Cush @RheumNow (  View Tweet)
May 06, 2021
#LupusAwarenessMonth Dr. Kathryn Dao - Pregnancy Outcomes in Lupus, SpA From ACR 2020 https://t.co/TvlqwZqgOv https://t.co/UBeVghYh0g
Dr. John Cush @RheumNow (  View Tweet)
May 06, 2021
Join us each Tuesday for Tuesday Night Rheumatology. We'll have new speakers each week and a Q&A session available following the discussion. https://t.co/ugGaPvBsLD https://t.co/CCua5Uvl7f
Dr. John Cush @RheumNow (  View Tweet)
May 06, 2021
Study of healthcare resource utilization and costs psoriasis, psoriatic arthritis (PsA) vs controls; PsA has the highest annual all-cause healthcare costs per patient - Controls =$7,470, Psoriasis= $11,062, and PsA = $29,742 https://t.co/06irRupcLJ

Dr. John Cush @RheumNow (  View Tweet)

May 06, 2021
Systematic review 6 studies of ischemic stroke and Idiopathic inflammatory myopathies (IIM) shows among 5,114 IIM cases there was an increased risk of ischemic stroke (RR = 2.41, 95% CI: 1.31, 4.45), 49% higher in dermatomyositis and Asian IIM. https://t.co/gYdMgmU5Uh

Dr. John Cush @RheumNow (  View Tweet)

May 06, 2021

Drug Monitoring Ineffective with Infliximab Treatment

May 05, 2021

The predictive value of therapeutic drug monitoring (TDM) while on biologics is debateable; gastroenterology routinely relies on TDM, while rheumatologists do not. A randomized trial compared TDM to no TDM in patients receiving infliximab for chronic immune-mediated inflammatory diseases (IMIDs) and found that TDM did not increase the odds of achieving remission. 

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News Feature: Autoimmune Thyroid Disease in Women JAMA has posted an insights article reviewing autoimmune thyroid disease in women. Thyroid autoimmunity has a higher prevalence in women and with increasing age. https://t.co/P55lMMagyO https://t.co/yMWJClvVJO
Dr. John Cush @RheumNow (  View Tweet)
May 05, 2021
Did you miss last night's Tuesday Night Rheumatology? Watch the playback now. https://t.co/8fjseHpSQV https://t.co/x4NSftQuRQ
Dr. John Cush @RheumNow (  View Tweet)
May 05, 2021
News Feature: Results Disappoint for Fecal Transplant in Arthritis Fecal microbiota transplantation (FMT) showed disappointing results among patients with active psoriatic arthritis, a small randomized trial found. https://t.co/US96DAa9XR https://t.co/IzWZJJe1RX
Dr. John Cush @RheumNow (  View Tweet)
May 05, 2021
May is Lupus month! We've compiled some great lupus resources to share throughout the month. #LupusAwarenessMonth Dr. Janet Pope - Modifying risk of Lupus and RA From ACR 2020 https://t.co/f8a6vHB31e https://t.co/8jteX3F5qg
Dr. John Cush @RheumNow (  View Tweet)
May 05, 2021
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