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11 RCTs (4,329 pts) & 19 registries (9,739 pts) studied Rx efficacy in CTD pts w/ pulmonary HTN. Overall, Rx (Sildenafil, Treprostinil, Bosentan, etc) reduced mortality 36% vs controls. CTD‐PAH survival was lower (52% v 72%) vs PAH; higher after 2010 https://t.co/IFb3nLiJbL

Dr. John Cush @RheumNow (  View Tweet)

Apr 10, 2021
New podcast available--Mistakes with Steroids Dr Jack Cush gives his spin on this week's news featured on RheumNow. Download wherever podcasts are available. https://t.co/cUI65I9759 https://t.co/fOWJXW50nI
Dr. John Cush @RheumNow (  View Tweet)
Apr 10, 2021

Anti-inflammatory Diet Control of Rheumatoid Arthritis

Apr 09, 2021

The TOMORROW study assessed the relationship between diet and disease activity in rheumatoid arthritis (RA) patients and has shown that RA patients are more likely to have higher inflammatory diets, but that a change to an anti-inflammatory diet resulted in lower disease activity scores.

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HLA-B27 status does not change the risk of COVID-19 in spondyloarthritis patients. Survey of 3435 SpA pts; shows 76% as HLA-B27 positive. COVID infx was thesame between B27 Pos & Neg pts (1.5% vs 1.4%) and severity was also the same https://t.co/qavodFynr0

Dr. John Cush @RheumNow (  View Tweet)

Apr 09, 2021
Axial Involvement in SpA: A Patient-Centered Exploration Sponsored by Novartis Medical Affairs Listen to Ethan Craig, MD, MPH present insights from patient cases to distinguish axial involvement within the spectrum of SpA. https://t.co/o2q5pTP3WD https://t.co/IXHs0LHSOe
Dr. John Cush @RheumNow (  View Tweet)
Apr 09, 2021
#RNL2021 coverage from @DrPetryna Refractory RA by Dr. Buch: -active DZ after >2 b/ts DMARDs -why rfRA exists: ?Immunologic heterogeneity of RA ?contributing co-morbidities ?unidentified Rx target -effective Rx in early disease decreases risk of future rfRA" https://t.co/ecrbqlvemf
Dr. John Cush @RheumNow (  View Tweet)
Apr 09, 2021
News Feature: Rheumatology Care Derailed by COVID-19 A survey study from the ArthritisPower PPRN or CreakyJoints database shows that during the COVID-19 pandemic patient care was substantially affected in unforeseen ways. https://t.co/BqY0vJpdm8 https://t.co/nZcuL4FbEw
Dr. John Cush @RheumNow (  View Tweet)
Apr 09, 2021
Don’t underestimate the utility of Vitamin D for VTE ppx in APS patients. Everyone should get some sun #RNL2021 Coverage from @doctorRBC #RheumNow

Dr. John Cush @RheumNow (  View Tweet)

Apr 09, 2021
Top March Tweet: The FDA approved tocilizumab for use in Systemic Sclerosis-Associated Interstitial Lung Disease for "Slowing the rate of decline in pulmonary function in adult patients with SSc-ILD" Rec dose is 162 mg SC q week (IV dose not approved) https://t.co/HXTRPiYEfZ

Dr. John Cush @RheumNow (  View Tweet)

Apr 09, 2021

Overview of New VEXAS Syndrome

Apr 08, 2021

Medscape offers up an informative overview of the newly described syndrome called VEXAS discovered by researchers at the National Institutes of Health. These patients were previously misdiagnosed with Sweets syndrome, relapsing polychondritis, myelodysplastic syndrome, MGUS, or polyarteritis nodosa – but were now unified by a somatic (UBA1) mutation.

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GLP-1 Therapy in Knee Osteoarthritis

Apr 08, 2021

Knee osteoarthritis is best managed by weight loss, as the effects of most analgesic therapies have been marginal and debatable. The use of anti-diabetic glucagon-like peptide-1 therapies have demonstrated significant weight loss benefits; hence this trial evaluated the potential weight loss and pain relieving effects of liraglutide in obese patients with KOA.

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#RNL2021 Coverage from @KDAO2011 "Psoriatic Arthritis Pearls by Dr. E Ruderman -MTX monoRx is effective -which TNFi does not matter -Secukinumab 300 mg is better than 150 mg dose -OK to use IL-17i in pts with FHx of IBD" #RheumNow

Dr. John Cush @RheumNow (  View Tweet)

Apr 08, 2021
News Feature: Reactogenicity Following mRNA COVID-19 Vaccines https://t.co/z1yGEG5TMs https://t.co/o6eYArgkqu
Dr. John Cush @RheumNow (  View Tweet)
Apr 08, 2021
Great #RNL2021 coverage from @uptoTate #RheumNow Not all that is pink and scaly is Psoriasis! DDx can include Sezary, Granuloma Annulare, Pemphigus, Erythroderma, paraneoplasm, eczema, lichen, basal cell CA, AKs, allergens, etc. Melodie Young, NP

Dr. John Cush @RheumNow (  View Tweet)

Apr 08, 2021
Survey study of 1221 RA patients and 414 rheumatologists shows both believe tha low-dose steroids (GCs) are very rapid and effective in RA control. Half patients reported having serious adverse events & 83% had safety concerns. https://t.co/h2GIYChYUL

Dr. John Cush @RheumNow (  View Tweet)

Apr 08, 2021
News Feature: Cost Efficacy of Knee Replacement in Obese Osteoarthritis Total knee replacement (TKR) in obese patients with end-stage knee osteoarthritis appears to be a beneficial and cost-effective strategy for treating. https://t.co/tnzqufjhBb https://t.co/6lNf27lrTL
Dr. John Cush @RheumNow (  View Tweet)
Apr 08, 2021
A Patient-Centered Exploration of Axial Involvement in SpA Sponsored by Novartis Medical Affairs Listen to a medical expert differentiate axial involvement within the spectrum of spondyloarthritis. https://t.co/o2q5pTP3WD https://t.co/fi0CQqxVmr
Dr. John Cush @RheumNow (  View Tweet)
Apr 08, 2021

Can Targeting RANKL in RA Heal Erosions?

MedPage Today
Apr 07, 2021

Treatment with denosumab (Prolia) helped heal bone erosions over 2 years among patients with rheumatoid arthritis whose disease activity was well controlled, researchers reported.

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Have you listened to last week's podcast? It's available wherever podcasts are available. Upadacitinib Wins in PsA https://t.co/Pd7QG6SsmJ https://t.co/3onAtZyoTt
Dr. John Cush @RheumNow (  View Tweet)
Apr 07, 2021
From @DrPetryna for #RNL2021 ------ Dr. Buttgereit on steroids in RA: 2.5 mg/d of prednisone increase total steroid amount in the body by 100% - great therapeutic effect but comes w/plethora of side effects. Q: how do you feel out long term low dose steroids for RA?"

Dr. John Cush @RheumNow (  View Tweet)

Apr 07, 2021
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