Recent News

  • A Dentist’s Three Tips to Stay on Muscarinic Agonists in Sjögren's Disease

    Jiha Lee, MD
    Dental tools
    Resolution of dryness remains a key unmet need for patients with Sjögren disease (SjD), as highlighted by the Sjögren SIG session “How to treat SjD” on the final day of APLAR 2026. A rheumatology talk in the session noted that recent phase III trials of ianalumab, dazodalibep and telitacicept improved ESSDAI scores, with only some evidence of benefit for dryness itself. Symptomatic care therefore still carries the load. Masafumi Moriyama, DDS, PhD, offered practical insight from the oral health side,
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Dr. John Cush Tweet
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Intra-Articular Injections for Knee OA: Options, Evidence, and no Clear Winner At APLAR 2026 in Seoul, the OA special interest group offered a whirlwind overview of IA injectables from Dr. Gun-il Im. The products fall into three tiers: symptom-modifying, biologic/regenerative https://t.co/jWuinfM2W6
article

The Concern about Seronegative RA

Jack Cush, MD

A current review of seronegative RA (SNRA) by D’Onofrio, et al in npj Autoimmunity shows the diverse fate of seronegative RA - which can resolve, persist or become refractory. Clearly dedicated trials of SNRA are needed to better predict.

Dr. John Cush Tweet
@RheumNow
Exagen studies 192 established RA pts (383 controls) for Abs: CCP2, RF IgA, RF IgM, PAD4 (IgA, IgG). RA signif assoc w/ CCP2+ (OR 110), RF (>7), PAD4 (3.5-5.9). In CCP neg - only PAD4 IgG (2.87) & RF (2.2) assoc w/ RA, w/ only small Dx gain (ΔAUC 0.02–0.04). https://t.co/isf7aMf24O
Dr. John Cush Tweet
@RheumNow
Spanish Nationwide registry study of 5120 hospitalised #GCA pts (2016-2024) found that 54 (1.1%) Dx / aortic aneurysm (AA) & 41 (0.8%) developed AA on F/U (AAf group). Median time to AA Dx 2.7 yrs. AA Risk was higher in males (RRR 2.42) & smoking w/ GCA (RRR 3.23) https://t.co/eZVGKbOfQt
sheila Tweet
@RHEUMarampa
Key messages from Dr. Vaidya’s talk: - Assocn’s of hyperuricemia or gout with MetS shows a bidirectional trend - Causality: MetS as an upstream driver for gout devt Going beyond jt dse & ULT. What addt’l assessments do you do for your gout pts? @RheumNow #APLAR2026 https://t.co/M6XVoRQ5rz
Jiha Lee Tweet
@JihaRheum
Perspective from dentists on SjD dry mouth: muscarinic agonists (pilocarpine, cevimeline) help, but side effects limit use. Two ways to improve it: split pilocarpine dosing (2.5 mg four times daily) and a cevimeline mouth rinse in 6 or more divided doses. #APLAR26 @RheumNow https://t.co/phiLD0qaoR
sheila Tweet
@RHEUMarampa
The growing unmet needs of repro health in the @APLAR_org region lead to dev’t of new consensus statements Provides a practical guide for rheums focusing on key areas like preconception, meds safety in pregnancy & men w/AIRDs planning to become fathers etc @RheumNow #APLAR2026 https://t.co/xCKmpcD4ma
Jiha Lee Tweet
@JihaRheum
Same molecule, different route, different persistence: golimumab IV persisted 4.44 yrs vs 2.07 for SC in biologic-naive RA (n=9,464, Korean claims). Is it the route, or differenntial out of pocket cost, or supervised dosing and better adherence? P#240 #APLAR26 @RheumNow

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Therapeutic Updates

Individualized PsA Treatment With an IL-23i or a JAKi

Sponsored by AbbVie Medical Affairs + Health Impact
AbbVie November RX Update
In Part 2 of our PsA management series, Saakshi Khattri, MD, and Lindsay Tom, PA-C, discuss tailoring treatment for patients with multidomain PsA and how IL-23i and JAKi data guide their decisions
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