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Beyond Chondrocalcinosis - What’s New in CPPD Disease
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Jack Cush, MD

Oct 29, 2026

An overview of calcium pyrophosphate deposition (CPPD) disease by Sara Tedeschi presents our evolving understanding of CPPD with advances affecting nomenclature, classification, imaging, genetics, long-term outcomes and potential future targeted therapies. This review builds on other important reports on CPPD.
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Patients with type 2 SLE present with fatigue, pain, brain fog and mood changes. Type 1 & 2 often coexist but type 2 SLE impacts QOL. @RheumNow #lupus #APLAR2026 https://t.co/aMtoIprPWG

https://x.com/RHEUMarampa/status/2115970283438051839/photo/1

Excites to report on #APLAR26 in Seoul, S. Korea for @RheumNow along with Drs. @RHEUMarampa and Peter Nash https://t.co/QImSxM7Izi

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24-Week Interim Findings from a Randomized Phase 2 Study of Iptacopan (LNP023) Indicate High Remission Rates in Participants with Active ANCA-Associated Vasculitis https://t.co/cUNMo2ngeE and liver safety over time is?

24-Week Interim Findings from a Randomized Phase 2 Study of Iptacopan (LNP023) …

CDR209: A Novel TRBV9×CD3 T Cell Engager for Precision Depletion of Disease-Associated T Cells in Axial Spondyloarthritis https://t.co/RPD7FkgEdQ anti-TRVB and anti-TRAV for your B27 AxSpA patients ( and needs looking at B27 positive PsA ) watch this space

CDR209: A Novel TRBV9×CD3 T Cell Engager for Precision Depletion of Disease-Ass…

Schett : in vivo the future if it works, during LD aciclovir, co-trimoxazole, CAR-T expansion amount not associated with toxicity, 3 month no vaccination window, all tissues B cell depletion , naive b cells return APLAR Seoul 2026 #CART #RheumNow

number of naive-like CAR-T infused associates with prolonged survival but highly variable APLAR Seoul 2026 #CAR-T #Rheum Now

Chan Hong Kong prediction CRS 80/20 - 80% CRS 20% hypoxia hypotension etc predictors 4 groups b cell load and IL6 level APLAR Seoul 2026 #CART #RheumNow https://t.co/Q3C9RaYPFz

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Georg Schett : cure prime goal of therapy! remission off all treatment , APLAR Seoul 2026 #CART #RheumNow https://t.co/kygOGdxUSe

https://x.com/drpnash/status/2115698926141726949/photo/1

lymphodepletion depends on individual cytokine profile and fludarabine PK effects efficacy APLAR Seoul 2026 #CAR-T #Rheum Now

Raff - Creative - lipid nanoparticle delivery APLAR Seoul 2026 #CART #RheumNow https://t.co/1O11I5pR8P

https://x.com/drpnash/status/2115707989630058734/photo/1

“Complex to manage” in SLE not for biologics APLAR Seoul 2026 Nikpour #SLE #RheumNow https://t.co/4qeRGEVijs

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ExVivo advantages APLAR Seoul 2026 #CART #RheumNow https://t.co/db2jIVDaik

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why biologics for “refractory”only - a life on steroids HCO MMF etc? APLAR Seoul 2026 Nikpour #SLE #RheumNow https://t.co/Fa58nsF5Mk

https://x.com/drpnash/status/2115997515338379749/photo/1

Prof. Sandra Navarra on GCs in #lupus : “There is NO safe threshold for Prednisone” Pred use follows a linear risk: As the dose of prednisone increases, damage risk doubles - - - > higher cataract, fracture and CV risks! @RheumNow #APLAR2026 https://t.co/8GGrwkcd8Q

Saag GIOP guidelines APLAR Seoul 2026 #GIOP #RheumNow https://t.co/HIEHcaQDeO

https://x.com/drpnash/status/2116001702998642747/photo/1

Oswestry Disability Index in axSpA (n=107, India): a patient-reported, low-cost, quick tool that tracked closely with BASDAI (r=0.77), BASFI (r=0.80) and ASDAS-CRP (r=0.79). Could help where rheumatologists are scarce. P#478 #APLAR26 @RheumNow https://t.co/teoMtnM3Gl

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evidence T2T in SLE is wortwhile APLAR Seoul 2026 Nikpour #SLE #RheumNow

Saag Osteoporosis - what to do when stopping Denosumab ? APLAR Seoul 2026 Nikpour #SLE #RheumNow https://t.co/skeONgWUpH

https://x.com/drpnash/status/2115999992028807378/photo/1

Schett - in remission : 14 normal pregnancies no SLE recurrence , babies normal b cells APLAR Seoul 2026 #CART #RheumNow

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Therapeutic Updates

PsA Beyond the Joints: Rheum, Derm, and Gastro Perspectives

Sponsored by AbbVie Medical Affairs + Health Impact

Oct 01, 2026

Dr. Saakshi Khattri hosts dermatologist Dr. Ahmad Amin and gastroenterologist Dr. Joshua Steinberg to discuss multidisciplinary care in PsA and other immune-mediated inflammatory diseases. Learn how signals in the skin and gut may prompt the need for collaboration across specialties to support better patient outcomes that extend beyond the joints.

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