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RheumNow Podcast – Can RA Be Prevented (12.7.18)

Dr. Jack Cush reviews the news and new journal articles from the past week on

  1. J. Hopkins study of 27 pts with inflammatory arthritis due to immune checkpoint inhibitors (mostly European ancestry) shows higher rate (61.5%) of at least 1 Shared Epitope allele (similar to RA pts) but were more likely to be seronegative for RF or CCP
  2. Retrospective study of 65,093 obese adults w/ bariatric surgery shows that, although Rouxen-Y gastric bypass had more wt. loss than gastric sleeve > gastric banding; RYGB had more 30-day major adverse events - Gastric Sleeve wins?
  3. Interdisciplinary guidelines for treating Uveitis in JIA - 1) Topical steroids; 2) if not improved, MTX; 3) Then TNF inhibitor; 4) systemic steroids; or 5) other biologics (TCZ, ABA, RTX). 
  4. Cohort study 56866 RA/PsA/AS patients compared 287 w/ multiple myeloma & 2760 matched controls - no difference in MM risk related to biologic, DMARD or NSAIDs. But compared to DMARD only pts, Biologic + DMARD users had a 48% lower risk of MM (OR 0.52)   
  5. Depression worsens back pain; increases healthcare costs. Medicare claims study 73,000 found 6,739 with back pain & 20% of these (1310) had depression. Annual healthcare costs substantially higher in LBP pts w/ depression ($13,153 vs $7,477, P < 0.001).   
  6. The Benefits of a Lupus Clinic    
  7. PRAIRI Study - Can RA Be Prevented?  
  8. New ACR/NPF Guidelines for Management of Psoriatic Arthritis
  9. RheumNow Live: March 2019 in Fort Worth – what determines whether you go to a medical meeting?
    1. Site/Venue
    2. Faculty
    3. Topics
    4. Time away
    5. Cost 



The author has received compensation as an advisor or consultant on this subject

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