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Substudy of 131 Still’s dz pts from the Autoinflammatory Dz (AIDA) registry. 38% underdosed w/ canakinumab (CAN) vs 62% appropriately dosed (300 mg q4wks or 4 mg/kg). Underdosed CAN had lower odds of long-term remission & D/C CAN (3.9% vs 19%) https://t.co/l94zB9NkKv https://t.co/D8FNUXS0nv
Dr. John Cush @RheumNow ( View Tweet )
31 minutes 51 seconds ago
🚨NEW FROM EULAR: In biologic-naive PsA, how do IL-23i, TNFi, and IL-17i compare on joint outcomes? 🦴Real-world data on TJC/SJC now available. Sponsored by AbbVie Medical Affairs + Health Impact. https://t.co/G5N7MPxnGu https://t.co/9cFpPP0JlW
Dr. John Cush @RheumNow ( View Tweet )
2 hours 2 minutes ago
CDC warns of an association betw severe CNS arboviral disease, w/ neurologic sequelae in pts receiving anti-CD20 mAbs (rituximab, ocrelizumab, ofatumumab, obinutuzumab, etc). West Nile virus was the most common arbovirus, but there are others; mortality up to 40%. Most arbovirus https://t.co/WWg41fsRgr
Dr. John Cush @RheumNow ( View Tweet )
3 hours 31 minutes ago
From 1975 -2025, incidence of Kawasaki dz (KD) increased 16.1-fold in Japan, KD cases 15 032 and& 14 809 in 2023 & 2024, but during COVID #s dropped to 10 333 in 2022. KD #s rebounded after the COVID-19: Infants showed minimal changes, but kids 5-9 had the greatest increase https://t.co/j0BL2ZELXn
Dr. John Cush @RheumNow ( View Tweet )
17 hours 32 minutes ago
Tune in for an expert conversation on the latest data from SELECT-SWITCH, including discussion about the EULAR 2026 post hoc analysis of primary and secondary TNFi nonresponders. Sponsored by AbbVie Medical Affairs + Health Impact. https://t.co/ni7IdVFobf https://t.co/Nb2Zb6WXDs
Dr. John Cush @RheumNow ( View Tweet )
19 hours 2 minutes ago
Simple infographic on the MOA of deucravacitinib (Sotyktu). https://t.co/fXbxMAzvAE https://t.co/6IvA0Xz3m2
Dr. John Cush @RheumNow ( View Tweet )
19 hours 50 minutes ago
MoonLake announced positive phase 3 data from its IZAR-1 RCT using its dual A/F IL-17 inhibitor sonelokimab, showing significant responses at week 16: 66% ACR20, 42% ACR50, 41% minimal disease activity (MDA), & 61% PASI90 at week 16. a 2nd IZAR-2 PsA RCT is in progress https://t.co/eX0cxekRKG
Dr. John Cush @RheumNow ( View Tweet )
20 hours ago
NP Salaries: in 7 specialties, NPs now avg >$150,000/yr, with the avg annual salary surpassing $137,000 in 2026 according toBureau of Labor Statistics. https://t.co/LlGFxkvEj5 https://t.co/h5bKsrnm4k
Dr. John Cush @RheumNow ( View Tweet )
21 hours 17 minutes ago
Multimodal & multidisciplinary Tx (MMT) are underutilized in adults w/ chronic pain. Study of 347 Chr pain pts - 60% used non-opioid meds; 29% used opioids & only 11% MMT. Older age & high intensity pain assoc w/ Opioids. MMT had more complex pain w/ greater pain interference, https://t.co/iF0UQeut9b
Dr. John Cush @RheumNow ( View Tweet )
22 hours 32 minutes ago
JAMA has updated its guidance for the acceptable use of AI in authoring a Medical Publication. Despite growing AI use, very low rates of disclosure of AI use have been reported. This is about what is permitted & not permitted & what needs to be disclosed. https://t.co/zti0OnvBV0 https://t.co/Y1C3MfJ27c
Dr. John Cush @RheumNow ( View Tweet )
1 day 2 hours ago
JAMA Patient Education Page on: Therapeutic Use of Cannabis and Cannabinoids https://t.co/s6F7B9qLfr https://t.co/lpLGozJgvi
Dr. John Cush @RheumNow ( View Tweet )
1 day 17 hours ago
Study of 154 anti-Ku Ab+ pts (51 IMMM, 46 SLE, 30 Sjögrens, 27 Sc) = 60 (39%) had ILD - 75% progressed; more rapidly in males. BUT Ku+ is rare <4%, not specific, without clear clinical implications. Ku is a myositis-assoc Ab (like Ro52/Ro60, U1-RNP, PM/Scl) https://t.co/MHz8mdqDqi
Dr. John Cush @RheumNow ( View Tweet )
1 day 21 hours ago
UK Clinical Practice Research Database study RA pts 3134 on glucocorticoids (vs not 4142 matched controls). were identified. GC use assoc w/ signif risk of SSRI initiation risk - recent GC (adj OR 1.53) & past GC (aOR 1.40). GC effect or confounding dz activity? Think depression! https://t.co/WZLkQWlURC
Dr. John Cush @RheumNow ( View Tweet )
1 day 23 hours ago
NSAIDs reduces age-related macular degeneration. TriNetX study (2015-2024) looked at non-AMD pts & showed NSAID use (n 634794) had signif less AMD at 6 mos (HR 0.31), 1 yr (0.36), 3 yrs (0.42) & 5 yrs (0.48); w/ signif protective effect (HR 0.58), Same for ASA (0.72) & https://t.co/Cgxrz92Omt
Dr. John Cush @RheumNow ( View Tweet )
1 day 23 hours ago
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