Drug-induced interstitial lung Dz accounts for 3⁻5% of ILD. Most common causes include Cancer drugs, followed by rheumatology drugs, amiodarone and antibiotics, - there is no typical radiological pattern specific to DIILD. Mortality rates as high as 50%. https://t.co/T7H6Y7qiI7

Federal register publishes new Trump admin plans to require drugmakers include list prices in direct-to-consumer television ads. This is subject to a 60-day comment period. 25 companies run ~300 DTC ads, TV ad spending >$2.8 billion in 1st 9 mos of 2018. https://t.co/QQrAT1BXZt

8 pts from the Toronto Lupus clinic dx w/ antimalarial cardiomyopathy by endomyocardial Bx. They were older 62.5 yrs, Dz duration 35 yrs, HCQ use 22 yrs, half w/ abnl cMRI; look for cardiac troponin I, high CPK. 1 died, other improved w/ HCQ d/c https://t.co/U7ZP0VhdCm

TNFi in Sarcoid? Metanalysis of 65 studies, 5 RCTs, 1525 pts shows no good data for ETN, GOL, CZP. But LIMITED Limited evidence of efficacy for infliximab in PULM, Skin, Ocular, CNS & multisystem Dz & adalimumab for Skin & ocular sarcoidosis https://t.co/aI1poTFrAl

Diabetics known to have a higher risk of hip Fracture; Metanalysis of nearly 5 million people & over 50k Fractures shows diabetics w/ a 30% increased risk of ankle Fx (RR 1.30) & 15% decrease in wrist Fx (RR 0.85). Same pattern of Fx seen w/ obesity. https://t.co/9J2A7Gqlhj