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From BiTE to TriTE: Progress of T-cell Engagers in RMDs At EULAR 2026 in London, T-cell engagers drew attention as a strategy to achieve deep B-cell depletion and drug-free remission in refractory RMDs. BiTEs offer off-the-shelf availability, reversible toxicity from short https://t.co/jjXrf9tcaA
Dr. John Cush @RheumNow ( View Tweet )
2 hours 35 minutes ago
How many CAR-T’s do we need to test drive? There were 93 abstracts with CAR-T in title at #EULAR2026! Additionally, there was an excellent review (WIN) by Dr. Hector Chinoy. We know lots but have more questions. https://t.co/dGpfffaubX https://t.co/3MS1ZjQExj
Dr. John Cush @RheumNow ( View Tweet )
4 hours 35 minutes ago
Single center study of 102 pts starting JAK inhibitor (72% >50yrs; 77% RA) shows only 27.5% received at least one RZV vaccination dose (Shingrix) & only 3 recv RZV within 30 daysof a JAK inhibitor. ????? (I vaccinate everyone going on a JAKi w/ Shingrix - don't you?) https://t.co/7HUqGGBeJ8
Dr. John Cush @RheumNow ( View Tweet )
6 hours 35 minutes ago
MTX: SC vs Oral? Metanalysis of 9 RCTs, 974 RA pts. Compared w/ oral, SC MTX signif. incr odds of ACR20 (RR=1.15), ACR50 (RR=1.14) & reduced GI adverse events (RR=0.58), diarrhea (RR=0.42): BUT no difference in ACR70, DAS28-ESR, bioavailability AUC, or other AE https://t.co/54xVnerRuS
Dr. John Cush @RheumNow ( View Tweet )
8 hours 31 minutes ago
Missed a session at EULAR 2026? No problem. The RheumNow Faculty Reporter team was on the ground covering the studies, debates, and breakthroughs that are shaping the future of rheumatology. From JAK safety and CAR-T therapies to advances in lupus, psoriatic arthritis, and ILD, https://t.co/cKmhq8mAIf
Dr. John Cush @RheumNow ( View Tweet )
22 hours 35 minutes ago
Late-breaking abstracts presented at EULAR addressed a wide range of clinical concerns and suggested that patients and clinicians have much to look forward to in coming months and years. https://t.co/m04h8eI3ZM https://t.co/HOQNA5gc6k
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
EULAR 2026 Recommendations on PMR, GCA, and Takayasu Arteritis On the final day of EULAR, Mukhtyar et al (on behalf of a large international task force) presented the updated EULAR recommendations for management of PMR, GCA, and TAK. There were 5 overarching principles and 12 https://t.co/kpykylEbsr
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
The North American Expert Consensus on ASCVD Screening in Lupus Nephritis Drs. Sheila Reyes and Shivani Garg discuss abstract OP094, presented in London at the EULAR 2026 Congress https://t.co/Vm2QFlO3fL https://t.co/4Xp9tkubLh
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Usual testing for SSA (Ro) pos. in Sjogrens identifies both Ro52 + Ro60 Abs, found in 70% of SjD. Pts who are double pos (Ro52+Ro60) have more severe dz, more Bcell activity. Ro60+ have milder dz; Recent report shows SjD pts have Ro60-specific CD4 T cells, activating Bcells https://t.co/SqoLICHOkS
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Prevalence of GI involvement in dermatomyositis (DM) was assessed in 2 cohorts (n = 167). Severe GI involvement seen in 18% NXP2+ & 6% MDA5+; more common w/ NXP2 than other DM (HR 8.85). NXP2 w/ severe GI dz were younger, facial edema @dx w/ both skin & muscle dz activity. https://t.co/5kNvAkTLc0
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Genicular artery embolization (GAE) in knee OA? Multiple open label studies & metanalyses suggest a clear pain benefit; BUT 3 sham-controlled RCTs have not demonstrated a statistically significant benefit over placebo. GAE is not addressed by ACR or EULAR guidelines. https://t.co/4JPm7gzCue
Dr. John Cush @RheumNow ( View Tweet )
2 days ago
From Cytokine Endotypes to Clinical Reality in Still’s Disease Recent EULAR 2026 data highlight a paradigm shift in Still’s disease from syndromic management to biologically informed precision therapy. https://t.co/FrghBJdlXj https://t.co/CbHYDKbnK9
Dr. John Cush @RheumNow ( View Tweet )
2 days 3 hours ago
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