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Registry of 587 #SLE pts. 30% were RNP+ --> more dz activity than RNP- (SLEDAI-2 8.0 vs 4.0) and more Rx use (daily GC 6.8 vs 3 mg). RNP+  more renal, skin & serologic activity & less likely to LLDAS (20% vs 32%) or REM (12% vs 23%). RNP + 18-fold more likely to be Sm+ https://t.co/9i3BBGA0uu
Dr. John Cush @RheumNow ( View Tweet )
4 minutes 18 seconds ago
Vitamin D in Rheumatic Disease - Is It Good Enough? Vitamin D in rheumatic disease — is it sufficient? Vitamin D deficiency/insufficiency is common and linked to inflammatory rheumatic diseases, raising the question of whether low vitamin D drives immune dysregulation, disease https://t.co/Xd8s8LKqKT
Dr. John Cush @RheumNow ( View Tweet )
18 hours 4 minutes ago
Parvovirus B19 Infection - Images from JAMA Dermatology. 40yoM 2-days asymptomatic rash w/ fever to 39°C, w/ arthralgias, Rash on BL cheeks, inguinal, flanks, axilla. WBC =2K, CRP 1.24 mg/dl. Dx by PCR for parvovirus B19 DNA https://t.co/LGGnabvFvA https://t.co/XzPlaWkIfz
Dr. John Cush @RheumNow ( View Tweet )
20 hours 4 minutes ago
Applying updated ACR guidelines in real life isn’t always straightforward. Two experts share insights on managing lupus nephritis beyond the textbook. Sponsored by Aurinia https://t.co/Zfu8ij8DNe https://t.co/nFVJenDkqc
Dr. John Cush @RheumNow ( View Tweet )
22 hours 4 minutes ago
An IL-23i through ~5 years: How did clinical manifestations of PsA and radiographic progression change during long-term treatment? 🔥View the latest long-term data from ACR to find out more. Sponsored by AbbVie Medical Affairs + Health Impact. https://t.co/zXHqLw5mTI https://t.co/uMr6kcTXkz
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Meet the RheumNow #EULAR2026 Reporting Team Delivering real-time insights from the forefront of rheumatology: 🩺 Dr. Antoni Chan (@synovialjoints) 🩺 Dr. Mrinalini Dey (@DrMiniDey) 🩺 Dr. Jiha Lee (@JihaRheum) 🩺 Dr. Aurelie Najm (@AurelieRheumo) 🩺 Dr. Janet Pope https://t.co/zpIeGWpL6P
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Toll-Like Receptor Drugs Effective in Cutaneous Lupus Enpatoran, an investigational oral drug that inhibits Toll-like receptors (TLR) 7 and 8, was superior to placebo in relieving lupus skin manifestations in a dose-finding phase II trial. https://t.co/R1wbJHXwjD https://t.co/65HtG0Te94
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Lupus Mortality Risk in Young Women New research using death certificate data from 52,942 females, reveals that systemic lupus erythematosus (lupus) is a leading cause of years of potential life lost among young women in the United States, underscoring the disease’s significant https://t.co/2FSINr6gZN
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Branebrutinib (Bruton's tyrosine kinase inhibitor) was studied in phase 2 RCT of 85 RA pts for 12 weeks and was safe but failed to achieve an ACR50 response (19% BTK vs 33% PBO; p=0·16). https://t.co/gTjLJm9iIW https://t.co/GN9p1P8ZNJ
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
RA adds to mortality risk in nontuberculous mycobact. infx (NTM). Retro study 1420 NTM pts, 66 (4.6) had RA. RA was independent predictor of resp-death (HR 4.30) - partly explained by ILD & systemic inflammation https://t.co/S9bndHsXCE https://t.co/mC74Qve1LZ
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
NEJM reports a 10 yrs study of Arthroscopic Partial Meniscectomy (APM) for Degenerative Tear — randomized, sham-surgery–controlled RCT of 147 pts w/o Knee https://t.co/WMGRIOunwZ 10 years, found no signif benefit betw APM and Sham surgery (pain, function) & possible worsening https://t.co/979C7IYuyZ
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
UCB has aquired Candid Therapeutics for $2 billion; plan to lead in autoimmune dz by acquiring cizutamig - a T cell engager. Its been studied in >100 pts, including early Global Phase 2 RCTs of myasthenia gravis & ILD. https://t.co/xz4uEhvxu6 https://t.co/6FS1riLecW
Dr. John Cush @RheumNow ( View Tweet )
2 days ago
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