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Bundibugyo virus disease (BVD) outbreak in the Congo in 2026. BV is an orthoebolavirus (not Ebola virus) species. Of the 2351 reported, 505 (22%)confirmed by PCR & 19% died. Sxs: Most 20-39 yrs, F>M, Fever (74%), GI & diarrhea (67%), anorexia, Abd pain (37%). HA (42%), SOB (34%), https://t.co/yYSmPjuiZW
Dr. John Cush @RheumNow ( View Tweet )
2 hours 2 minutes ago
Where are we with Biomarkers in Rheumatoid Arthritis? Biomarker interest has grown considerably in the last 2 decades, owing to advances in genetics, imaging, protein, and multiomics. Despite these advances, biomarkers as the predictive holy grail of RA therapeutics and https://t.co/ggoWx8yumZ
Dr. John Cush @RheumNow ( View Tweet )
4 hours 1 minute ago
B cell Targeting in SLE Prospects are growing that an approved, off-the-shelf drug can rescue patients with certain ultra-refractory autoimmune diseases, a pair of new reports suggest. https://t.co/wGaZPnXfID https://t.co/a0fNvdcrbQ
Dr. John Cush @RheumNow ( View Tweet )
5 hours 32 minutes ago
RHEUM SURVEY> Do you prefer a lupus drug if it has a lupus nephritis indication (when your treating non-renal SLE)? Answer here >> https://t.co/1KridYM9n8 https://t.co/zIqNB5Mc0O
Dr. John Cush @RheumNow ( View Tweet )
6 hours 32 minutes ago
NEJM on anti-CD19 CAR-T cell therapy in B cell lymphoma - 38 pts w/ refractory NHL (24 lg B-cell, 1414 follicular lymphoma) Rx w/ CTL019. 10-yr survival = 32% w/ large B-cell & 47w/ follicular lymphoma; Persistent neutropenia 5%, & 2nd primary cancer seen in 21%. B-cell aplasia https://t.co/CPKvunGZxl
Dr. John Cush @RheumNow ( View Tweet )
7 hours 2 minutes ago
Redefining axial spondyloarthritis An editorial in Lancet Rheumatology calls for "..reframing axSpA as a systemic, autoimmune inflammatory disease with multiorgan involvement and substantial unmet need." https://t.co/C1Kei8AU3h https://t.co/lspQYyEFHa
Dr. John Cush @RheumNow ( View Tweet )
21 hours 2 minutes ago
U Maryland study found that 5-minutes of proximal intercessory prayer (PIP) — in-person prayer offered by a trained volunteer — significantly reduced pain and anxiety in primary care patients compared to a music control group. 180 pain pts (pain >4/10) w/ > 2 pt reductions at 2 & https://t.co/k4JiQvyC31
Dr. John Cush @RheumNow ( View Tweet )
22 hours 32 minutes ago
Up to 80% of Brucellosis has MSK Sxs (half in the spine/SI). CDC reports in the USA 2010–2024 1,796 confirmed and probable cases - 61% reported travel (80% Intl travel). Most exposures consumed unpasteurized dairy products or undercooked meat 73%], 62% had animal contact and 40% https://t.co/Njpf71jwKd
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
4-week, proof-of-concept, PBO-controlled RCT Rx 30 Depression pts w/ either PBO or tocilizumab. No improvement by day 14, but over time TCZ pts improved depressive Sxs & severity, fatigue, anxiety, & QOL. Remission seen in 54% vs 31%, favoring TCZ. https://t.co/FpdZJikf8C https://t.co/IaKP3JXARa
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
Redefining axial spondyloarthritis An editorial in Lancet Rheumatology calls for "..reframing axSpA as a systemic, autoimmune inflammatory disease with multiorgan involvement and substantial unmet need." https://t.co/6uLv16aOcX https://t.co/a3NxMdnI9F
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
RHEUMATOLOGIST POLL> ?How valuable is a Lupus Nephritis Indication when treating NON-RENAL lupus? Answer here>> https://t.co/K4aikzZRmY https://t.co/60wM3XJE8n
Dr. John Cush @RheumNow ( View Tweet )
1 day ago
No Fetal Risks with First Trimester NSAID Use PLoS Medicine has published a population-based retrospective cohort study from the Southern Israeli Pregnancy Registry (siPREG) project showing that 1st trimester exposure to NSAIDs was not associated with major congenital https://t.co/ZVUOizbcdg
Dr. John Cush @RheumNow ( View Tweet )
1 day 6 hours ago
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