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WSJ: Nurse Practitioner Is Now the Hottest Job in Healthcare

The Wall St. Journal has published a perspective on nurse practitioners (NP) and their very promising careers.

RepurpSS-II: Hydroxychloroquine plus Leflunomide in Sjögren's

A small, pilot, phase 2b trial has shown that the combination of leflunomide and hydroxychloroquine (LEF+HCQ) was effective and safe in treating patients with active Sjögren's disease.

Trends and Innovations in Lupus Nephritis Clinical Trials

Xu et al. from Shanghai University have written an analysis of global lupus nephritis (LN) clinical trials and call for innovation.

Quiz Talk (5.22.2026)

Dr. Jack Cush talks of birthdays, Quizzes and journal articles this week on the podcast.

BE BOLD Week 16 data - Bimekizumab vs. Risankizumab in PsA

UCB has released the Week 16 results from BE BOLD trial that will be presented at EULAR 2026 in London on Saturday, June 6.

A Role for Plasmacytoid Dendritic Cells in Lupus

Plasmacytoid dendritic cells (pDCs) have been strongly implicated in the pathogenesis of lupus, as their primary product, type I interferon, drive systemic lupus erythematosus and cutaneous lupus erythematosus. A recent comprehensive review synthesizes the available data on pDCs, and, importantly, what we still don't know.

Early GI Involvement Predictive of Scleroderma Outcomes

Rheumatology has published a cohort study showing that earlyGI symptoms and overall symptom burden predict both GI progression and mortality in Systemic Sclerosis (SSc).

Hydroxychloroquine: 5 mg/kg/day Is Only the Starting Point

Hydroxychloroquine (HCQ) is one of the most important drugs in rheumatology, especially for systemic lupus erythematosus (SLE). It reduces flares, organ damage, cardiovascular events, and pregnancy complications, and it improves survival.

Immune-Mediated Inflammatory Diseases Following Uveitis

A Korean insurance claims data study showed children and adolescents diagnosed with uveitis have a 7-fold increased risk of developing an immune-mediated inflammatory disorder (IMID).

Does Exercise and Lifestyle Modification Improve RA?

Does exercise or lifestyle modifications reduce the risk of getting rheumatoid arthritis (RA) or change those with early RA?

ABA versus HCQ in Palindromic Rheumatism

Palindromic rheumatism may develop rheumatoid arthritis (RA) and could be an at-risk population. A pilot trial compared abatacept (ABA) versus hydroxychloroquine and demonstrated ABA reduces RA development in a 2 year study. 

Update on Multicentric Reticulohistiocytosis

Have you ever seen multicentric reticulohistiocytosis? Don't worry, it's a rare non-Langerhans cell histiocytosis condition, characterized by papulonodular skin lesions and symmetric erosive polyarthritis, and has only been described in fewer than 500 cases reported worldwide.
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