AS/Spondyloarthritis

Eric Dein ericdeinmd
2 years 9 months ago
@RheumNow video from #ACR22
Opioid use in PsA and SpA patients
Discussing abstract 1012 by @AlexisOgdie
https://t.co/fKRog1aIkH

Richard Conway RichardPAConway
2 years 9 months ago
Jones et al. Non-smokers, normal BMI, and current drinkers! with AxSpA more likely to respond to TNFi. @RheumNow #ACR22 Abstr#1510 https://t.co/inCz2sAyj5 https://t.co/K27ptuLV7Y


Janet Pope Janetbirdope
2 years 9 months ago
#ClinicalPearl woman with non-radiographic axSpA have LESS inactive disease vs MEN but NOT true if radiographic axSpA. 5 yr global study N=2633, independent of TNFi use - not sure why there are differences. Misclassification dx- unlikely. abst#1614 #ACR22 #ACRBest @RheumNowNews https://t.co/coNjwHOkLP


Richard Conway RichardPAConway
2 years 9 months ago
Kiltz et al. Greater efficacy of secukinumab in normal BMI than high BMI AS patients. Decremental effect with increasing BMI. @RheumNow #ACR22 Abstr#1495 https://t.co/zwEmQsJmPT https://t.co/nOW2IbTc5t


Richard Conway RichardPAConway
2 years 9 months ago
Benesova et al. Higher treatment response to secukinumab in both male and female AS patients when diagnosed earlier. No such effect seen in PsA patients. Emphasises need to reduce diagnostic delay in AS. @RheumNow #ACR22 Abstr#1497 https://t.co/9g2zN85a33 https://t.co/LfvQFTKr69


Richard Conway RichardPAConway
2 years 9 months ago
Torgutalp et al. Higher NSAID intake associated reduced spinal progression in AxSpA esp. r-AxSpA. Cox-2 may have greater effect than other NSAIDs. @RheumNow #ACR22 Abstr#1492 https://t.co/bGH6bBo7AD https://t.co/XBFV410Y2p


Dr. Rachel Tate uptoTate
2 years 9 months ago
CorEVITAS Abs 1499 #ACRbest #ACR22 cycling to a second line TNFi provides limited benefits to pts with AxSpA who discontinued a first line TNFi. @RheumNow
https://t.co/fKDa5kPfXN https://t.co/CtMCj2Ihgc


Richard Conway RichardPAConway
2 years 9 months ago
Papagoras et al. Serum GM-CSF increased in AxSpA and persists despite TNFi. Are we going to have a trial of mavrilimumab in AxSpA then? @RheumNow #ACR22 Abstr#1156 https://t.co/wCFsY9nC1p https://t.co/lrQQ7tIX4x


Dr. Rachel Tate uptoTate
2 years 9 months ago
Delay in AS dx appeared to be BMI-dependent in female pts and both genders n PsA dx. In contrast to AS, SEC treatment response of early- and late-diagnosed PsA pts did not differ. Abs 1497 #ACR22 @RheumNow https://t.co/LBo3XapAT4 https://t.co/uAcfeiED4F


Dr. Antoni Chan synovialjoints
2 years 9 months ago
Lower socioeconomic status (cluster 1) patients:
● older age at the diagnosis (37.9 vs. 32.6)
● longer diagnosis delay (7.8 vs. 6.8 years)
● higher BMI (27.6 vs. 25.9)
● greater structural damage
vs cluster 2
Lopez-Medina C Abs0376 https://t.co/wXOksFGDKl #ACR22 @RheumNow https://t.co/1YVRA6r1sw


Dr. Antoni Chan synovialjoints
2 years 9 months ago
Patients with PsA and AS who used opioids had higher healthcare utilization and higher costs. Also
➣ more comorbidities
➣ higher prevalence of smoking
➣ worse disease activity
➣ higher use of anti-rheumatic drugs
Ogdie A Abs0402 https://t.co/3E4qAuqgpI #ACR22 @RheumNow https://t.co/AaKxiQXMwx


sheila RHEUMarampa
2 years 9 months ago
Lifestyle modifications can affect tx response with TNFi in axSpA!
Accdg to this study fr Prof GJones, ✳️Smokers, overwt & obese pts are ⬇️ likely to achieve treatment response to TNFi vs. nonsmokers & normal wt pts
Smoking cessation, wt mgt is key!
#ACR22 @RheumNow ABST#1510 https://t.co/PBFcj6zKVD
