Psoriatic arthritis
 
  Robert B Chao, MD doctorRBC
            2 years 11 months ago 
          
         
          BE COMPLETE study:
Bimekizumab (IL-17A and IL-17F inhibitor) efficacious in phase 3 trial for treatment of PsA. No new safety signals. 
Abs#1599 @RheumNow #ACR22 https://t.co/iXj7wSRNeK
        
         
 
  Dr. Rachel Tate uptoTate
            2 years 11 months ago 
          
         
          Abs 1507 at #ACR22 demonstrated that even a 6-month delay in PsA dx  from symptom onset contributes to worse patient-reported outcomes measures on overall quality of life. @RheumNow https://t.co/qLOwE9rImz https://t.co/nacdjz5pCy
        
        
       
 
  Dr. Rachel Tate uptoTate
            2 years 11 months ago 
          
         
          The likelihood of a patient self-reporting LDA/REM and specificity of MDA score were unaffected by which MDA criteria were met. @DrLauraCoates et al, Abs 1496 #ACR22 @RheumNow https://t.co/xH70swdZZ0 https://t.co/Wct0emTaDt
        
        
       
 
  Olga Petryna DrPetryna
            2 years 11 months ago 
          
         
          #Abs1260 #acr22 @rheumnow #acrbest Clincial&US eval 54 RA &18 PsA pts: Tenderness aasoctd w/radiographic progress in non-swollen jnts in PsA but not in RA. In tender non-swollen jnts in RA pts, baseline erosions& sonographic synovitis  had significant impact on radio progression https://t.co/iqWvHiDeq8
        
         
 
  Dr. Rachel Tate uptoTate
            2 years 11 months ago 
          
         
          RZB is efficacious in reducing signs and symptoms of PsA in patients, regardless of patterns of joint involvement Abs 1504 #ACR @AlexisOgdie @RheumNow https://t.co/AIEJbqrqBf https://t.co/kyiocs8TmL
        
        
       
 
  Dr. Rachel Tate uptoTate
            2 years 11 months ago 
          
         
          Sonographic enthesitis is assoc'd w/ sonographic synovitis and tenosynovitis in PsA. Abs 1498 #ACR22 @RheumNow https://t.co/tssYZ55iMq https://t.co/C7Dk66rwVA
        
        
       
 
  Dr. Rachel Tate uptoTate
            2 years 11 months ago 
          
         
          Delay in AS dx appeared to be BMI-dependent in female pts and both genders n PsA dx. In contrast to AS, SEC treatment response of early- and late-diagnosed PsA pts did not differ. Abs 1497 #ACR22 @RheumNow https://t.co/LBo3XapAT4 https://t.co/uAcfeiED4F
        
        
       
 
  Olga Petryna DrPetryna
            2 years 11 months ago 
          
         
          #abs1235 #acr22 @rheumnow
articular fibroblast activation in PSO assessed by 68Ga-FAPI-04 PET-CT assoctd w/⬆️ risk of developing PsA. 10 pts assessed: 6/7 pts (85.7%)w/ 68Ga-FAPI-04 uptake at synovio-entheseal sites progressed to PsA. median PsA-free time 207 (160-240)days https://t.co/Y6EHPaDwfh
        
         
 
  Dr. Rachel Tate uptoTate
            2 years 11 months ago 
          
         
          PsA pts starting 1st DMARD tx, both early & late initiators experienced dz activity and PRO improvements up to 6 months post-initiation. Better response, including MDA, achieved in pts initiating DMARD tx w/in 1 yr of dx. Abs 1493 #ACRbest #ACR22 @RheumNow https://t.co/a94sZRQ3VF https://t.co/OSUEoChtFf
        
        
       
 
  Patricia Harkins DrTrishHarkins
            2 years 11 months ago 
          
         
          🌟PSA vs RA 🌟
-UK cohort 
PSA associated with:
👉⬆️ duration symptoms prior 2 referral
👉⬆️ interval between GP presentation and DX
👉⬇️DMARD commencement 
👉⬇️ improvement in Dx activity @ 3/12 
# We need to do better 
#ACR22 Abst#1613  @RheumNow
        
         
  Dr. Rachel Tate uptoTate
            2 years 11 months ago 
          
         
          There is an association between the severity of skin and joint or axial disease, both at baseline and longitudinally, in pts presenting w/in 12 months of diagnosis of PsA. Abs 1511 #ACR22 @RheumNow https://t.co/PcVn6dITqU https://t.co/qxn3LBOW8d
        
        
       
 
  Robert B Chao, MD doctorRBC
            2 years 11 months ago 
          
         
          Even a 6 month delay in PsA diagnosis can lead to worse PROs on quality of life!
Likelihood of depression increased
Pts with PsA dx in <6 months reported better outcomes
Abs#1507 @RheumNow #ACR22 https://t.co/igCiH22CWi
        
         
 
  Dr. Rachel Tate uptoTate
            2 years 11 months ago 
          
         
          GUS (compared to RIS) uniquely binds both CD64+ myeloid cells and IL-23. CD64+ mononuclear phagocytes are enriched in the psoriatic skin and serve as the dominant IL-23 source. Does this lead to a change in clinical response?  Abs 1487 #ACR22 @RheumNow https://t.co/P512bxSxRn
        
        
       
  Patricia Harkins DrTrishHarkins
            2 years 11 months ago 
          
         
          ‼️FAP (fibroblast activation protein) 
PET-CT in PsA‼️
⚡️synovial and entheseal accum in PsA v HC 
⚡️correlation of uptake with pain scores 
⚡️IL-17A ⬇️ FAP, with arrest joint damage 
⚡️persistent FAP - ⬆️ prog joint damage 
❓new T2T in PsA❓
#ACR22 @RheumNow Abst#1602
        
         
  

 
 
 
 
 
 
          
           
    
 
 
 
 
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