Psoriatic arthritis
Day two at ACR 2022 was full of great sessions on imaging, vasculitis, lupus, vasculitis, spondyloarthritis, COVID, pregnancy, microbiome, economics and more.
Here are the RheumNow faculty…
2 years ago
@RheumNow video from #ACR22
Opioid use in PsA and SpA patients
Discussing abstract 1012 by @AlexisOgdie
https://t.co/fKRog1aIkH
A clinician faces several vexing diagnostic dilemmas, multiple times during a busy time in the clinic. Is this Seropositive RA with psoriasis or psoriatic arthritis (PsA) with a marginal…
2 years ago
Ab1012 #ACR22
@AlexisOgdie Opioid Use & Healthcare Utilization in PsA and AS
21% PsA pts on opioids, 27% AS on opioids
Opioid users - more co-morbidities, 🚬, worse disease
Tended to higher use of anti-rheumatic drugs
Higher health care utilizations, medical $$
@RheumNow
2 years ago
CASIPSA results: CT SIJ characteristics from PsA pts similar to age- and sex-matched controls, but w/ higher prevalence of erosions, found in 18% of PsA patients. Abs 1012 #ACR22 https://t.co/jdUSUoUUbf https://t.co/2NQOhncYFc
2 years ago
To propose early intervention in pre-clinical PsA we need to first identify pts!
Eder et al. PRESTO Prediction of Psoriatic Arthritis Tool
Dvlped 600+ Pso
M stiff, PASI, nails, fatigue pain severity
Sens 61% Spe 77% for 5% proba PsA onset w/in 5yrs
Abs#1612 #ACR22 @Rheumnow https://t.co/QYOIKe3nui
2 years ago
Tapryal et al. Diagnostic delay of >6 months contributes to poor PROs in PsA. @RheumNow #ACR22 Abstr#1507 https://t.co/dkaNhXUAeD https://t.co/6G7X7V1aRI
2 years ago
Karmacharya et al. Multimorbidity in PsO strongly influences incident PsA, >=2 comorbidities HR 2.53, >=5 comorbidities HR 3.19. Also higher for non-white, HR 4.02, and decreased with age. @RheumNow #ACR22 Abstr#1506 https://t.co/OFobRzhQVL https://t.co/IP08XlD66H
2 years ago
Benesova et al. Higher treatment response to secukinumab in both male and female AS patients when diagnosed earlier. No such effect seen in PsA patients. Emphasises need to reduce diagnostic delay in AS. @RheumNow #ACR22 Abstr#1497 https://t.co/9g2zN85a33 https://t.co/LfvQFTKr69
2 years ago
Promising results for Izokibep in PsA
Ph2 RCT meets primary endpoint at Wk 16
ACR50: 13% PBO 48% 40mg IZO 52% 80mg IZO
MDA: 5% PBO 42% 40mg 39% 80mg
Results observed as soon as wk2
No new safety signal compared to IL17Ai
https://t.co/Gilhg5k36b
Abs#1597 #ACR22 @RheumNow https://t.co/VvxSRLtkFk