
Robert B Chao, MD doctorRBC
2 years 5 months ago
Plenary session III:
Intensive diet and exercise program in overweight/obese pts with knee OA showed significant reduction in weight, pain and function, greater walk distance and quality of life.
Abs#1675 @RheumNow #ACR22 https://t.co/vstfJahLQV


Richard Conway RichardPAConway
2 years 5 months ago
Bruce et al. Rheumatic disease onset/flare with ICI assoc good tumour response in melanoma. OR = 14.151 @RheumNow #ACR22 Abstr#1668 https://t.co/870ODwva5n https://t.co/bcneKZbeC4


Richard Conway RichardPAConway
2 years 5 months ago
Bass et al. Treatment ICI-arthritis. Tricky one. MTX alone assoc longer time to cancer progression and to arthritis control compared to combination with bDMARD. Thoughts @drdavidliew ? @RheumNow #ACR22 Abstr#1669 https://t.co/8KH8RZzcaZ https://t.co/DtpA8s4PLy


Robert B Chao, MD doctorRBC
2 years 5 months ago
Are your SpA pts planning on conceiving? Be careful with NSAID use
French study found age and NSAID use associated with longer time-to-conception.
Factors not associated: smoking, BASDAI score, DMARD use
#ACRBest Abs#1673 @RheumNow #ACR22 https://t.co/D63XTY7IB8


Eric Dein ericdeinmd
2 years 5 months ago
Ab1673 #ACR22: Time-to-Conception (T2C) in SpA
Prosp, observ
88F, 56 pregnancy
Subfertility in 45% F, T2C 16 mos
Risks: age, NSAID
Rx: NSAIDs (26%), steroids (9%), csDMARD (14%), biol (69%)
No control grp - Is it cause or correlate?
2020 Repro G/L rec d/c NSAID
@RheumNow #ACRBest https://t.co/e51XjhyH9u


sheila RHEUMarampa
2 years 5 months ago
☝️Treatment is the 3rd reason why we need to order a BL HRCT in pts with ILD; "We can't treat SSc-ILD if we are not able to detect SSc-ILD" - Dr. Elana Bernstein
#ACR @RheumNow #rheumatology https://t.co/ooZVSbt3Xf


Dr. Antoni Chan synovialjoints
2 years 5 months ago
Peresolimab humanized IgG1 mab
➢ stimulates PD-1 & physiological immune inhibitory pathways
➢ In RA phase 2 study, superior to placebo at Week 12 DAS28/CDAI
➢ safety events were similar between treatment groups
Emery P #L03 https://t.co/4Jd79CW5RA #ACR22 #ACRBest @RheumNow https://t.co/PSuLQgjYuz


Robert B Chao, MD doctorRBC
2 years 5 months ago
BE OPTIMAL Study - Bimekizumab (IL-17A and IL-17F inhibitor) for treatment of PsA.
Similar ACR 50 (~50%) response rates of Bimekizumab, adalimumab, and placebo (switched to BKZ at wk 16).
~60% PASI100 in BKZ
#ACRBest Abs#L02 @RheumNow #ACR22 https://t.co/W2B2kyju9F


Richard Conway RichardPAConway
2 years 5 months ago
Hamroun et al. Preconceptual NSAID use assoc impaired fertility in SpA, HR 3.01 for time-to-conception @RheumNow #ACR22 Abstr#1673 https://t.co/jresR9MfXF https://t.co/flyfJob9un


Catherine Sims, MD DrCassySims
2 years 5 months ago
Congratulations @RheumNow @rheum_cat @CreakyJoints 🎉 #ACR22 https://t.co/P7iLUPnt0p

Eric Dein ericdeinmd
2 years 5 months ago
Ab1674 #ACR22 HCQ in pregnancy is SAFE and Standard of Care!
In Utero Exposure to HCQ does NOT ass w/ ocular toxicity: OCTs 5 yrs after birth 👀
PATCH study of HCQ to reduce CHB in pregnancy
18% CHB (historical) -> 7% treated risk
OCT: retinal thickness nml at 5 yrs
@RheumNow

TheDaoIndex KDAO2011
2 years 5 months ago
#CurbsideConsult. What would you do? 45 yo female with dSSc and ILD, had been on stable MMF 1500 mg bid. she had increased SOB, new dry cough, hand pain, stiffness.Exam noted synovitis, Labs: ESR 76, Echo RSVP 25 mmHg, HRCT increased ILD compared to a year ago. #ACR22 @rheumnow

David Liew drdavidliew
2 years 5 months ago
Are TNFi or IL-6Ri safe in rheumatic irAEs from ICI Rx?
Multiple big US centers retrospective:
TNFi, IL-6Ri vs MTX
p>0.05, but may be approx 2x risk of cancer progression
Has made me more cautious about TNFi, IL-6Ri - use MTX when you can
Lovely work! ABST1669 #ACR22 @RheumNow https://t.co/cfAT1pQZ7I


TheDaoIndex KDAO2011
2 years 5 months ago
This is how Dr. Berstein manages SSc-ILD #ACR22 @rheumnow #CurbsideConsult https://t.co/vP7m0WpdK6


Richard Conway RichardPAConway
2 years 5 months ago
Abdel-Wahab et al. TCZ in combo with ipilimumab/nivolumab. Very preliminary results of what will be important trial. Appears safe and well-tolerated with no increased risk cancer progression. @RheumNow #ACR22 Abstr#1670 https://t.co/uPBnHJ9BRH