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      #0775
      Higher circulating microbial small RNA tDR-1 linked to lower risk of developing RA in CCP3+ individuals (AUC 0.86)

      Mrinalini Dey DrMiniDey

      2 weeks ago
      #0775 Higher circulating microbial small RNA tDR-1 linked to lower risk of developing RA in CCP3+ individuals (AUC 0.86). tDR-1 downregulates interferon-response genes in vitro, suggesting microbiome-mediated anti-inflammatory mechanism in RA pathogenesis. @RheumNow #ACR25
      SLE & arthritis: Is there a difference?
      Abstract #0629:
      - Non-deforming (ND): 73% | Jaccoud’s: 19% | Rhupus: 8%
      -

      Akhil Sood MD, MS AkhilSoodMD

      2 weeks ago
      SLE & arthritis: Is there a difference? Abstract #0629: - Non-deforming (ND): 73% | Jaccoud’s: 19% | Rhupus: 8% - Vs ND, Rhupus had lower odds of type I IFN signature - Time to deformities: Jaccoud's ~2 yrs vs Rhupus ~5 yrs - RNP+ predictive of Jaccoud’s @RheumNow #ACR25
      Why do some clinics excel at RA disease activity tracking while others struggle? In the VA, success came down to structu

      Jiha Lee JihaRheum

      2 weeks ago
      Why do some clinics excel at RA disease activity tracking while others struggle? In the VA, success came down to structure: RA-specific clinics, templates, and staff. Barriers? Time, missing labs, and workflow gaps. @RheumNow #ACR25 Abstract#0222
      Managing lupus is complex. How do we ensure quality care?
      Abstract #0218 convened 8 focus groups:
      ✅ Support for patien

      Akhil Sood MD, MS AkhilSoodMD

      2 weeks ago
      Managing lupus is complex. How do we ensure quality care? Abstract #0218 convened 8 focus groups: ✅ Support for patient navigators ⚠️ Barriers: low resources, staff turnover 💻 Solution: EHR outreach workflow to flag missed visits & labs @RheumNow #ACR25 https://t.co/BWaIMMEPit
      Abstract #0607: The age at diagnosis of SLE is rising in US based cohort📈
      Those diagnosed ≥30 yrs were:
      ⬆️ More

      Akhil Sood MD, MS AkhilSoodMD

      2 weeks ago
      Abstract #0607: The age at diagnosis of SLE is rising in US based cohort📈 Those diagnosed ≥30 yrs were: ⬆️ More likely to have oral ulcers, hematologic features, +ANA ⬇️ Less likely to have malar rash or proteinuria @RheumNow #ACR25 https://t.co/pMPVLg1xTZ
      Damen et al. 10-year follow-up of CRESPA study. Treatment withdrawl trial in early peripheral SpA. 38% in drug free remi

      Richard Conway RichardPAConway

      2 weeks ago
      Damen et al. 10-year follow-up of CRESPA study. Treatment withdrawl trial in early peripheral SpA. 38% in drug free remission. 82% in remission. @RheumNow #ACR25 Abstr#568 https://t.co/KOVW5pSbJg
      Abstract 0196: Too many referrals, too few slots? A hybrid RN + MD referral cut wait times for patients with SLE by 26%

      Akhil Sood MD, MS AkhilSoodMD

      2 weeks ago
      Abstract 0196: Too many referrals, too few slots? A hybrid RN + MD referral cut wait times for patients with SLE by 26% Median time to appointment 69 days --> 51 days Next steps: streamline high-risk triage, reduce manual chart review @RheumNow #ACR25
      DESIR cohort of early axSpA:
      ✳️Factors assoc w/ D2M axSpA - female sex, ⬆️ASDAS-CRP ⬆️BASFI ⬆️ASQOL at

      sheila RHEUMarampa

      2 weeks ago
      DESIR cohort of early axSpA: ✳️Factors assoc w/ D2M axSpA - female sex, ⬆️ASDAS-CRP ⬆️BASFI ⬆️ASQOL at baseline. ✳️ Low prevalence of pts meeting D2M definition (15 pts - 8.4% bDMARD-treated) #ACR25 @RheumNow Abs0544 https://t.co/fBUh3myKcz
      Abstract #0189: Rheumatologists are early adopters and high utilizers of #AI scribes.
      📊 Adoption: 41%
      🧑‍💻 Ret

      Akhil Sood MD, MS AkhilSoodMD

      2 weeks ago
      Abstract #0189: Rheumatologists are early adopters and high utilizers of #AI scribes. 📊 Adoption: 41% 🧑‍💻 Retention: 100% 💬 High utilizers (> 70% visits): 83%. The highest among IM subspecialties 🕒 AI scribes reduced EHR time across all measures. @RheumNow #ACR25 https://t.co/TBurWUKhMl
      Ramiro et al. No significant differences seen between men and women in response to upadacitinib in AxSpA at week 14 or 5

      Richard Conway RichardPAConway

      2 weeks ago
      Ramiro et al. No significant differences seen between men and women in response to upadacitinib in AxSpA at week 14 or 52. Differs from data on TNFi/IL17i in this regard. Looks to me like men respond a bit quicker and better though... @RheumNow #ACR25 Abstr#589 https://t.co/2m7mrgcG0z
      This retrospective cohort analysis by Dr. Lihi Eder et al showed that among patients with PsA, those w/ high dse activit

      sheila RHEUMarampa

      2 weeks ago
      This retrospective cohort analysis by Dr. Lihi Eder et al showed that among patients with PsA, those w/ high dse activity & high 3VAS scores were assoc w/⬆️ risk of atrial tachyarrythmias. Main message: PsA conveys ⬆️CV risk; inflamm control is key! #ACR25 @RheumNow Abs0522 https://t.co/7sRM7K4V1c
      In a nationally representative NHANES sample, inflammatory back pain (IBP) was not associated with HLA-B27 positivity or

      Antoni Chan MD (Prof) synovialjoints

      2 weeks ago
      In a nationally representative NHANES sample, inflammatory back pain (IBP) was not associated with HLA-B27 positivity or elevated CRP, regardless of IBP criteria used (e.g., Berlin 8a: OR 0.88, p=0.876). IBP alone may be insufficient for identifying axSpA-related immunogenetic or https://t.co/82NjVU171z
      What can we learn from longitudinal peripheral blood multi-omic profiling in at-risk individuals?

      50 RA converters vs.

      Aurelie Najm AurelieRheumo

      2 weeks ago
      What can we learn from longitudinal peripheral blood multi-omic profiling in at-risk individuals? 50 RA converters vs. non converters from StopRA study Decision tree showing highest risk for conversion to clinical RA in Individuals w/ -CCP3 ≥108 units -T peripheral helpers https://t.co/jw53EB6tI6
      #0774
      Multi-omic profiling of anti-CCP3+ “at-risk” individuals reveals Tph & cytotoxic CD8+ expansions, altered

      Mrinalini Dey DrMiniDey

      2 weeks ago
      #0774 Multi-omic profiling of anti-CCP3+ “at-risk” individuals reveals Tph & cytotoxic CD8+ expansions, altered gene/chromatin profiles and predictive model (AUC 0.77) for RA conversion PTPN22 locus accessibility & Tph ≥ 2.45% identify highest risk. @RheumNow #ACR25 https://t.co/JDSMkdmoGv
      Not just for salivary glands—lacrimal ultrasound helps too.

      In early Sjögren’s, lacrimal + salivary US clearly dis

      Jiha Lee JihaRheum

      2 weeks ago
      Not just for salivary glands—lacrimal ultrasound helps too. In early Sjögren’s, lacrimal + salivary US clearly distinguished SjD from sicca (AUC up to 0.97). Noninvasive, reproducible, and highly diagnostic. @RheumNow #ACR25 Abstract #0507
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