Recent News
Read ArticleA current large Rheumatoid arthritis (RA) cohort study from Cairo assessed methotrexate (MTX) use and found over half were MTX intolerant and a third of patients were noncompliant with MTX.A total of 355 RA pati
Canadas 2025 Top 10 Funded Research Projects
Arthritis Society
Arthritis Society Canada (ASC) is Canada’s largest charitable funder of cutting-edge arthritis research, investing more than $240 million in research projects since our founding, and over $7 million invested in 2024-2025.
ASC announced the grants they supported in 2025. Below are the investigators and projects that were funded in 2025.
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GC dose and tapering may influence serious infection risk in patients with GCA. Discover the key safety outcomes observed during a year of JAKi therapy in a Phase 3 trial. Sponsored by AbbVie Medical Affairs +Health Impact.
https://t.co/33NuP5or2V https://t.co/bDIuFuKmxZ
Dr. John Cush @RheumNow ( View Tweet)
TOPKAT Trial: Partial vs Total Knee Replacement
Patients with osteoarthritis (OA) primarily affecting only one knee joint compartment did just as well with partial knee replacement (PKR) as with total arthroplasty after 10 years in a randomized trial -- and maybe a little bit https://t.co/MNpVeHQbJ2
Dr. John Cush @RheumNow ( View Tweet)
DMARD Responses in Localized Scleroderma
JAMA Dermatology has published the results of a juvenile localized scleroderma (JLS) trial showing that mycophenolate mofetil (MMF) and methotrexate (MTX) are equally effective in treating JLS, noting low flare rates and possibly better https://t.co/BbIS5rdRYU
Dr. John Cush @RheumNow ( View Tweet)
“Play the game for more than you can afford to lose... only then will you learn the game.”
- Winston Churchill
Dr. John Cush @RheumNow ( View Tweet)
Full read review of the Mechanistic Effects of Methotrexate in the Treatment of Rheumatoid Arthritis. https://t.co/PrMyZ7q3wX download here: https://t.co/aRnmRm770Z https://t.co/5B0mBjzOXQ
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Dr. John Cush @RheumNow ( View Tweet)
B Cells at the Brink in Sjögren Disease
The current issue of Arthritis & Rheumatology reviews the current understanding of the immunopathogenesis of Sjögren disease (SjD) and how this understanding has informed drug development for this systemic autoimmune disorder. https://t.co/p3dn1Ca2ag
Dr. John Cush @RheumNow ( View Tweet)
Treat-to-Target in Gout and Cardiovascular Outcomes
A 5 year JAMA study shows that a treat-to-target (serum urate < 6 mg/dL) study finds that effective urate-lowering treatment (ULT) results in a significantly reduced cardiovascular risk in patients with gout. https://t.co/4j9c7DPHIu
Dr. John Cush @RheumNow ( View Tweet)
Clinical contributors to pathogenesis and treatment outcomes for rheumatoid arthritis. Full read review of pathogenesis and unmet needs in #RA https://t.co/IEC0tsp1Rk https://t.co/jIsqhy9rQh
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Dr. John Cush @RheumNow ( View Tweet)
Roche Canada announced that Health Canada has approved obinutuzumab (Gazyva) for the treatment of adult patients with active lupus nephritis who are receiving standard therapy. Following four initial doses in the first year, Gazyva can be administered twice yearly https://t.co/P4dCVkoPCH
Dr. John Cush @RheumNow ( View Tweet)
Testing for RF, CCP, ESR and CRP
Check out the accompanying Advanced Practice Rheum: Rheumatoid and Inflammation Testing video.
https://t.co/4hkDO1M2UD https://t.co/APRKYLAS3k
Dr. John Cush @RheumNow ( View Tweet)
APPIPRA Study - Benefits of Early Treatment
Treating people who are at high risk of rheumatoid arthritis (RA) can delay the onset of the disease for several years, with benefits also continuing well after treatment has stopped.
https://t.co/GYguq7VlqT https://t.co/5Z0BXIm3cM
Dr. John Cush @RheumNow ( View Tweet)
RheumNow Live Preview (1.30.2026)
Dr. Jack Cush reviews the news and journal reports from RheumNow.com - and the top 5 reasons to attend RheumNow Live 2026, which is one week away.
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NEJM - Baker’s Cyst
A 63-year-old woman with psoriatic arthritis presented with a 9-month history of pain in the left knee. A nontender, palpable mass was present in the left popliteal fossa, which had a “speech bubble” shape on ultrasonography. https://t.co/7wBnkDoUaX https://t.co/m0AhRnDc4c
Links:
Dr. John Cush @RheumNow ( View Tweet)
Expertise is valued by all, YET, (many consider) change might be risky. (happened w/ Hand-washing, antibiotics, smoking dangers, etc). "Just because the establishment doesn’t like it doesn’t mean it’s not a good idea. " - Seth Godin https://t.co/3vQ4eHa4jr https://t.co/9mIJwD1f7z
Dr. John Cush @RheumNow ( View Tweet)
Remission? Single center study of 100 RA, 100 SLE pts assessed by SLEDAI-2K, SDAI, VAS. Remission/LDA found in 88% of 392 SLE visits & 91% of 389 RA visits(p=NS). Remission was more common in SLE vs RA (79% vs 69%; p= 0.0018). https://t.co/ZPRrYQMsCT
Dr. John Cush @RheumNow ( View Tweet)
UK NHS has cut use of physician associates over ‘substitute doctor’ fear. The reduction in roles is being blamed by union leaders for an increasing in waiting times and consultants’ workload. Plus 76% of PAs said their scope of practice had been restricted in recent months. GMC https://t.co/i0l4x9UVhZ
Dr. John Cush @RheumNow ( View Tweet)
Physical activity (PA) is assoc w/ reduced all-cause mortality in RA pts. Study of 1493 NHANES & 1724 UK Biobank RA cohorts showing robust inverse association between PA and all-cause mortality (HR: active = 0.48, highly active = 0.61) https://t.co/K6ALzqP3QQ https://t.co/2XJ0zD7FA3
Dr. John Cush @RheumNow ( View Tweet)
PA Assn President position on DES/gov Proposed Rule on Federal Student Loans "... loan rule is deeply flawed, outside the Dept’s authority...inconsistent w/.. Trumps rural healthcare workforce priorities.. excluding PAs will decimate US healthcare workforce pipeline" https://t.co/p5owv3Ui2B
Dr. John Cush @RheumNow ( View Tweet)
From the Blog
Podcasts
DERM on RheumNow PODCAST (January 2026)
RheumNow Live Preview (1.30.2026)
Emergencies, Independence & Hemorrhage (1.23.2026)-
2025 Rheumatology Year in Review (1.16.26)
Therapeutic Updates
The Impact of Obesity on Psoriatic Arthritis
Sponsored by Lilly Medical Affairs
Obesity is common in PsA and may worsen disease activity and reduce treatment effectiveness through shared inflammatory pathways. Weight intervention may improve outcomes and support achievement of targets of disease control.
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Poster Hall
Sponsored by AbbVie Medical Affairs + Health Impact
