Friday, 28 Apr 2017

Today's Headlines

Elimination of Senescent Chondrocytes Reduces Post-Traumatic Osteoarthritis

A study in the April 24 issue of Nature Medicine suggests that senescent cells in the joint contribute to age-related degenerative disease and that their removal can abrogate disease. 

Best to Rehab at Home Following Joint Replacement

New York Times article sheds light on recent evidence suggesting that those undergoing hip or knee replacement will do just as well with home therapy compared to inpatient rehabilitation following surgery.

Pregnancy Flares in RA and Spondylitis

Despite the folklore, not all women with arthritis who become pregnant will improve or go into remission.  Recent studies have suggested that up to one-third of RA patients will flare during pregnancy.

This issue has been further examined in a cohort of 136 pregnant patients with RA and axial spondyloarthritis (axSpA) who were prospectively followed before, during, and after pregnancy.

EULAR/EFORT Taskforce on the Management of Fragility Fractures

The morbidity associated with osteoporosis-related fragility fractures imposes tremendous socioeconomic and medical impact on patients and society.

Consensus on OP Drug Holidays

Extending bisphosphonate treatment beyond 3–5 years does not confer additional benefit in low-risk populations. Treatment re-initiation (usually 1–3 years after bisphosphonate withdrawal) depends on risk factors, new fractures and bone mineral density. The evidence regarding denosumab discontinuation is limited but caution is advised, as there may be a “rebound effect” with regard to fractures.

BLOG

Historically, syphilis and tuberculosis were the “great masqueraders” in medicine.

My original agreement with Jack was to review a serious scientific book.  However, half way through one, I was bored, so I went to the library. I'm so glad I did, because I came upon two books, written by Ireland-born physician Patrick Taylor, that continued the tale I'd started years ago about Fingal Flahertie O'Reilly.

 

I had dinner about a month ago in Phoenix with Peter Lipsky, an icon in rheumatology and who requires no introduction to my readers, where we discussed a rambling number of topics both rheumatologic (hence, the experience does qualify for a blog!) and non-rheumatologic.
“It’s unbelievable how much you don’t know about the game you’ve been playing all your life.” - Mickey Mantle

This is going to be my third visit with this patient and I’m not looking forward to it.

RWCS 2017: Unsuspected Cause of Cardiomyopathy
/vef/load/05d21dbe97763a65eacd2391b82c922e?width=640&height=365

Social

Daily Download

High Risk for Serious Infection

RheumNow Live Vote

As biosimilar biologic agents become available, when will you use them?

This month’s Live Vote is being guided by Dr. Artie Kavanaugh and will focus on the rheumatologists' views on biosimilars.

View the Result