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DRESS Trial Shows TNFi Dose Reduction is Possible - Without Major Flares
Can TNF inhibitor therapy be withdrawn in RA patients who are in remission? The DRESS trial reports the results of randomized trial of 180 RA patients taking either etanercept or adalimumab. Patients were randomly assigned to either usual care (no dose reduction) or a stepwise increase
Read ArticleHLA-DRB1 Alleles Augment RA Severity and TNF Inhibitor Responses
The HLA-DRB1 haplotype is a known risk factor for RA.
Read ArticleWait a minute: how much to develop a new drug?
Older estimates suggested it would cost $1 billion to develop a new drug. ThisNY Times article discusses newer estimates claiming it cost 2.6 billion to bring a new drug to market.
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