ASDAS Activity Correlates with Xray Progression in Spondyloarthritis Save
Investigators analyzed a prospective study of patients with early axial spondyloarthritis (axSpA) to assess predictors of outcome.
Poddubnyy and coworkers studied 178 patients with definite axSpA and serially assessed disease activity using the Ankylosing Spondylitis Disease Activity Score (ASDAS) and radiographs to detect spinal progression.
They found a significant positive association between disease activity (by ASDAS) and radiographic spinal progression over 2 years of study. Xray (mSASSS) progression by ≥2 points over 2 years was significantly associated with the time-averaged ASDAS: unadjusted OR=1.64.
Syndesmophyte formation/progression demonstrated an even stronger association with the time-averaged ASDAS: unadjusted OR=2.62.
These data should encourage wider use of the ASDAS in assessing patients with axSpA.
ADD THE FIRST COMMENT
Disclosures
The author has no conflicts of interest to disclose related to this subject
If you are a health practitioner, you may Login/Register to comment.
Due to the nature of these comment forums, only health practitioners are allowed to comment at this time.