Wednesday, 12 Dec 2018

You are here

Calcium and Vitamin D Do Not Increase Cardiac Events/Death

An analysis of the UK Biobank study found no link between calcium/vitamin D supplementation and incident cardiovascular events/deaths in a large prospective study of 475,255 men and women aged 40 to 69 years.

Results published in Journal of Bone and Mineral Research used registry data to identify coded incident hospital admissions for ischemic heart disease (IHD), myocardial infarction (MI), and subsequent death.

Amond 475,255 participants 33,437 were taking calcium supplements; 19,089 vitamin D; and 10,007 both.

In crude and adjusted analyses, there were no associations between use of calcium supplements and risk of incident hospital admission with either IHD, or subsequent death.

The hazard ratio (HR) for myocardial infarction was 0.97 (95% confidence interval [CI] 0.79–1.20, p = 0.79) in  women taking calcium supplementation, and in men was 1.16 (95% CI 0.92–1.46, p = 0.22).

Results were similar for vitamin D and combination supplementation.

In this very large prospective cohort, there was no evidence that use of calcium/vitamin D supplementation was associated with increased risk of CV events.

Disclosures: 
The author has no conflicts of interest to disclose related to this subject

Add new comment

More Like This

No End in Sight for the Shingrix Vaccine Shortage

There is a national shortage of a new shingles vaccine, Shingrix, which is a problem for those who want to start the vaccine and those seeking to receive their second and final injection. 

Since its FDA approval nearly a year ago, sales of the new vaccine have outperformed projections and are expected to approach $1 billion in revenue for 2018. 

Patients Don't Always Tell the Truth

Sometimes patients withhold information from their doctors, and a new study suggests that as much as 60 - 80% of patients consciously omit information to their doctors, despite knowing this may bear on their health and well-being.

Deprescribing to Battle Polypharmacy

The Gerontological Society of America has published a report calling for deprescribing as a means of managing polypharmacy in the elderly.

Limited Impact of Vitamin D Supplementation

A systematic review of 81 studies on vitamin D concludes that vitamin D supplementation does not prevent fractures or falls, or have clinically meaningful effects on bone mineral density.

Metanalyses specifically looked at studies addressing total or hip fractures, falls, or bone mineral density measured at the lumbar spine, total hip, femoral neck, total body, or forearm.

Steroid Injection Superior to Splinting in Carpal Tunnel Syndrome

Lancet has published a comparative effectiveness study examining the the value of night splints (conservative treatment) vs local injection for patients with carpal tunnel syndrome.