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German investigators studied 100 RA patients with a uric acid > 6 mg/dl and assessed them for MSU crystal deposit with dual energy computed tomography (DECT) of both feet and hands.
These RA patients with hyperuricemia were mostly over 60 years of age with a disease duration of 8.7±10.5 years. Twenty out of 100 patients displayed MSU crystal deposits in DECT and the majority (70%) of these were seronegative RA patients. According to logistic regression model analysis, seronegative status correlated positively with presence of urate deposits (p=0.019).