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Comorbidities are common in patients with axial spondyloarthropathy (axSpA), and a recent study has shown that multimorbidity, the coexistence of 2 or more conditions, is associated with more severe disease than those without comorbidities.
Analysis of the the Ankylosing Spondylitis Registry of Ireland (ASRI) cohort looked for physician-diagnosed comorbid chronic condition (excluding extraarticular manifestations) and assessed disease activity with validated measures.
The study included 734 patients from 12 centers; most were male (77%) with a mean age 45 years.
Mulimorbidity was seen in 55% (403/734), with obesity as the most common chronic condition (27%).
Multimorbid patients had more severe disease than axSpA patients without comorbidities - having higher BASDAI, BASMI, BASFI, HAQ and ASQoL scores.