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Comorbidity Worsens Axial Spondyloarthritis

Comorbidities are common in patients with axial spondyloarthropathy (axSpA), and a recent study has shown that multimorbidity, the coexistence of 2 or more conditions, is associated with more severe disease than those without comorbidities. 

Analysis of the the Ankylosing Spondylitis Registry of Ireland (ASRI) cohort looked for physician-diagnosed comorbid chronic condition (excluding extraarticular manifestations) and assessed disease activity with validated measures.

The study included 734 patients from 12 centers; most were male (77%) with a mean age 45 years.

Mulimorbidity was seen in 55% (403/734), with obesity as the most common chronic condition (27%).

Multimorbid patients had more severe disease than axSpA patients without comorbidities - having higher BASDAI, BASMI, BASFI, HAQ and ASQoL scores.

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Disclosures
The author has no conflicts of interest to disclose related to this subject