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Enthesitis Ultrasound as an Outcome Measure in Spondyloarthritis

Musculoskeletal ultrasound (US) was recently used in a longitudinal study Achilles enthesis of 146 patients with early spondyloarthritis (SpA). Usual measures of SpA activity included BASFI, BASRI-spine, BASDAI and Ankylosing Spondylitis Disease Activity Score (ASDAS).

Baseline abnormal Achilles Dopplers were significantly associated with higher CRP and ESR levels. Patients who had very high disease activity at baseline, as assessed by the ASDAS (>3.5), had a significantly higher Achilles total US score at baseline (P = 0.04), and ASDAS 1.3 predicted no Doppler signal at 6 and 12 months. The Doppler signal at the baseline visit predicted a higher total US score at 6 and 12 months.

Doppler US of the enthuses was significantly associated with traditional SpA activity measures (ESR, CRP, ASDAS) and may be useful in clinical trials.

 

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Disclosures
The author has no conflicts of interest to disclose related to this subject