Tuesday, 15 Oct 2019

You are here

Improving Cardiovascular Trends in Rheumatoid Arthritis

 Myasoedova and colleagues from the Mayo Clinic have reported their new data that demonstrates improving cardiovascular (CV) mortality rates in current RA patients treated with modern drugs.

They studied 813 RA patients (mean age 55.9 years; 68% female). In patients with incident RA during the 2000–2007 period, the 10-year CV mortality was 2.8% (95% CI: 0.4%, 5.2%) and coronary heart disease (CHD) mortality was 1.2% (1.0, 1.4%). These numbers demonstrate significant improvement when compared to patients diagnosed in 1990–1999. Lower rates of CV outcomes included the overall CV death rate (HR=0.43; 95% CI: 0.19, 0.94; p=0.035); and CHD death (HR 0.21; 95% CI: 0.05, 0.95).

Importantly, the lowering of RA death rates now show them to not be different than the non-RA cohort (general population). 

Disclosures: 
The author has no conflicts of interest to disclose related to this subject

Add new comment

More Like This

Stress and the Risk of Incident Inflammatory Arthritis

A prospective analysis of newly diagnosed, inflammatory arthritis (IA) patients suggests that perceived distress (stress) increases the odds of incident IA.

Juvenile Arthritis at Risk for Coronary Artery Disease

Arthritis Care & Research reports that juvenile arthritis (JA) patients may have a higher risk if coronary artery disease (CAD) in adulthood. 

Data was drawn from the National Health and Nutrition Examination (2007‐2014).  The diagnoses of JA and CAD were self declared by respondents.

Long Delays for Inflammatory Arthritis Patients

The National Rheumatoid Arthritis Society's (NRAS) annual audit has identified significant treatment delays for patients with suspected early inflammatory arthritis could result in unnecessary harm. 

Antibiotics Increase Rheumatoid Risk - Again

Another UK study has suggested that prior use of antibiotics increases the risk of developing rheumatoid arthritis (RA).

Rheumatology has published a 15 year case–control study that compared 8482 newly diagnosed RA patients and 22,661 controls from the UK’s Royal College of General Practitioners Research and Surveillance Centre database (between 2006 and 2018).

Two vs. Four Weeks of Antibiotic Therapy in Septic Arthritis

A prospective trial has shown that 2 weeks of antibiotic therapy is as effective as 4 weeks of antibiotic therapy, with similar outcomes but shorter hospital stays.

This Swiss study was a prospective, unblinded, randomised, non-inferiority study comparing either 2 or 4 weeks of antibiotic therapy after surgical drainage of native joint bacterial arthritis in adults.