Wednesday, 18 Oct 2017

You are here

Lupus Hospitalizations are Common

Patients with systemic lupus erythematosus (SLE) incur substantial morbidity and complications that may lead to hospitalizations and increased cost of lupus care. Researchers from the University Health Network in Toronto have published a review of SLE hospitalizations showing thta while commone (for either infection or lupus activity), only 2.8% of hospitalizations resulted in death.

They identified all SLE hospitalizations at University Health Network between 2011–2012 and 2013–2015 to assess cause, extent of hospitalizations, and outcomes. 

They identified 247 SLE patients with a total of 491 hospitalizations. Most (87.4%) were women, with an average age of 43.9 years, and a mean disease duration of 13.7 years.  Thus SLE patients was averaged 1.6 hospitalizations lasting 8.5 days.

Incidental causes, such as adverse drug reactions or pain, were the most common reason for admission (36.0%). Next most common were admissions were because of active SLE and infection (21.4% and 22.4%, respectively). ICU admission was required in 13% and 2.8% of hospitalizations resulted in death.

Fewer hospitalizations were seen in those who were employed, those on antimalarials or with higher educational level.

Damage related to lupus correlated with increased hospitalizations. and antimalarial use correlated with shorter length of stay. 

Re-hospitalization was seen in nearly 40% of patients. 

Disclosures: 
The author has no conflicts of interest to disclose related to this subject

Add new comment

More Like This

BSR Guidelines on Lupus Management

In the UK, NICE has accredited the British Society of Rheumatology (BSR) to develop a guidance document on the management of systemic lupus erythematosus in adults.  The last published guidelines for lupus were published in 2008 by EULAR and in 2012 by the ACR.

IBD Associated with Increased risk of Autoimmune and Inflammatory Diseases

A registry based study has shown higher rates of immune mediated diseases (IMD) in patients with inflammatory bowel disease (IBD).

Researchers examined 47325 IBD patients from the Danish National Patient Registry and compared them to controls from a civilian registry and used ICD 10 codes to identify the diagnoses observed.

Primary Sjögren's Syndrome Guideline from the British Society for Rheumatology

The British Society of Rheumatology (BSR) has been accredited by NICE to develop a guidance document for the management of primary Sjögren's Syndrome intended for rheumatologists, general physicians, general practitioners, specialist nurses and other specialists (e.g. ophthalmologists, dental practitioners and ENT specialists),

Isolated SS-B Not Associated with Connective Tissue Disease

A one-year prospective study of 624 patients undergoing autoantibody testing for anti-SS-A and/or anti-SS-B autoantibodies finds that isolated anti-SS-B autoantibodies was not associated with features or the diagnosis of any specific connective tissue diseases (CTD).

Half of Takayasu's Arteritis Relapse

A French retrospective study of 318 Takayasu's arteritis (TA) patients shows that 50% of patients will relapse and experience a vascular complication ≤10 years from diagnosis.