Friday, 16 Feb 2018

You are here

Lupus Hospitalizations are Common

Patients with systemic lupus erythematosus (SLE) incur substantial morbidity and complications that may lead to hospitalizations and increased cost of lupus care. Researchers from the University Health Network in Toronto have published a review of SLE hospitalizations showing thta while commone (for either infection or lupus activity), only 2.8% of hospitalizations resulted in death.

They identified all SLE hospitalizations at University Health Network between 2011–2012 and 2013–2015 to assess cause, extent of hospitalizations, and outcomes. 

They identified 247 SLE patients with a total of 491 hospitalizations. Most (87.4%) were women, with an average age of 43.9 years, and a mean disease duration of 13.7 years.  Thus SLE patients was averaged 1.6 hospitalizations lasting 8.5 days.

Incidental causes, such as adverse drug reactions or pain, were the most common reason for admission (36.0%). Next most common were admissions were because of active SLE and infection (21.4% and 22.4%, respectively). ICU admission was required in 13% and 2.8% of hospitalizations resulted in death.

Fewer hospitalizations were seen in those who were employed, those on antimalarials or with higher educational level.

Damage related to lupus correlated with increased hospitalizations. and antimalarial use correlated with shorter length of stay. 

Re-hospitalization was seen in nearly 40% of patients. 

The author has no conflicts of interest to disclose related to this subject

Add new comment

More Like This

Nailfold Capillaroscopy Portends Prognosis in Systemic Sclerosis

Two reports underscore the importance of nailfold capillaroscopy (NFC) in scleroderma and have shown that nailfold capillary drop out was significantly associated with mortality in systemic sclerosis.

Poor Prognosis of the MDA-5 Antibody in Dermatomyositis

Researchers from Hong Kong assessed the clinical associations seen with the anti-melanoma differentiation-associated gene 5 antibody (anti-MDA5 Ab) assay in consecutive patients with dermatomyositis (DM) and polymyositis (PM).

Twenty patients with either DM or PM who were followed in the Rheumatology Clinic of Kwong Wah Hospital, Hong Kong were recruited and underwent testing for the anti-MDA-5 antibody.

Inefficacy of Immunosuppressive Treatments in Systemic Sclerosis with ILD

EUSTAR study results published in Arthritis Research & Therapy show the current state of immunosuppressive use in systemic sclerosis patients with interstitial lung disease (SSc-ILD) to be ill-defined, but that liberal use of glucocorticoids (GC) in SSc-ILD should be discouraged.

ESRD Death Declines in Vasculitis Patients


In the past 2 decades, mortality from end-stage renal disease (ESRD) among U.S. patients with granulomatosis with polyangiitis (GPA) has declined significantly, a nationwide study found.

Stroke Risk Confirmed in SLE

The most common cerebrovascular events (CVEs) seen among a large cohort of patients with systemic lupus erythematosus (SLE) were stroke and transient ischemia, and the majority of these events were attributable to the disease itself, a multinational study determined.