Tuesday, 31 Mar 2020

You are here

Microscopic Polyangiitis Associated with Pulmonary Fibrosis

Microscopic polyangiitis (MPA) is one of several vasculitides that affects the lung.  Its most common pulmonary complication is diffuse alveolar haemorrhage, which carries a significant morbid risk. MPA association with pulmonary fibrosis (PF) has been increasingly reported. Do MPA patients with PF have different characteristics and evolution to those of MPA patients without PF?
 
In the retrospective review of 28 patients, high prevalence of pulmonary fibrosis in MPA patients (32%) was observed and most of MPA-PF patients had a poor outcome as compared to non-PF group. PF was often the first manifestation of the disease.
Disclosures: 
The author has no conflicts of interest to disclose related to this subject

Add new comment

More Like This

In Lupus, Keep BP Below 130/80

Blood pressure should be maintained at a level below 130/80 mm Hg in all patients with lupus to lessen their likelihood of atherosclerotic vascular events, Canadian researchers asserted.

In Vasculitis, Beware of Infection

Risks of infection were strikingly high among patients with antineutrophil cytoplasmic antibody-associated (ANCA) vasculitis, which may relate to both the disease and its treatment, Scottish researchers found.

Malignancies with Giant Cell Arteritis

The Journal of Rheumatology reports the findings of a Swedish population-based cohort study of biopsy-proven giant cell arteritis (GCA) patients showing that the overall risk for cancer was not increased; yet there appears to be an increased risk for leukemia and a decreased risk for breast and upper gastrointestinal tract cancers.   

Hospitalized GPA - Higher morbidity, Mortality and Cost

Rheumatology reports on a study of patients with granulomatosis with polyangiitis (GPA) showing worse outcomes and higher costs when hospitalized with GPA.

GPA patients were identified from the Nationwide Inpatient Sample (NIS) and were compared to those without GPA with regard to demographics, procedures, length of stay, mortality, morbidity and total hospitalization charges (between 2005–2014).

Don't Blame the Weather in Sjogren's

Seasonal variations in symptoms -- commonly reported by patients with rheumatic diseases -- were not observed in a large cohort of patients with primary Sjogren's syndrome, French investigators found.