Wednesday, 14 Nov 2018

You are here

Patients May Not Fill Your Prescription

A new study linking administrative claims and electronic health records (EHRs) shows that nearly 40% of patients fill and take newly prescribed methotrexate (MTX), tofacitinib or biologics. 

Kan et al set out to estimate the extent and predictors of primary nonadherence in rheumatoid arthritis (RA) patients who received new prescriptions for methotrexate, biologics or tofacitinib. They found:

  • 36.8% of patients prescribed methotrexate failed to initiate methotrexate within 2 months;
  • 40.6% of patients newly prescribed biologics/tofacitinib failed to initiate within 3 months.

Predictors for methotrexate primary nonadherence included age, race, region, body mass index, number of active drugs and chronic cormbidities.

Factors associated with biologics/tofacitinib primary nonadherence included age, insurance, and certain comorbidities at baseline. 

Primary nonadherence to methotrexate and biologics/tofacitinib was common in RA patients. It may be possible to predict patients at high risk of primary nonadherence and intervene with measures to promote adherence.

Disclosures: 
The author has no conflicts of interest to disclose related to this subject

Add new comment

More Like This

CIRT Trial - Methotrexate Fails at Cardiovascular Prevention

Methotrexate has been shown to reduce cardiovascular (CV) deaths in rheumatoid arthritis (RA) patients. Given that inflammation underlies the pathogenesis of atherothrombosis, Dr. Paul Ridker and colleagues studied the value of low dose methotrexate (MTX) in preventing cardiovascular events.

ACR 2018 Podcast - Day 3

Audio Highlights and Interviews from Day 3 at the ACR 2018 meeting  LISTEN HERE

ACR 2018 - Day 3 Report

Highlights from Tuesday, day 3 of the ACR Annual meeting in Chicago, included:

The PEXIVAS Study –  2x2 Trial of Plasma Exchange and Reduced Steroids in ANCA-Associated Vasculitis (AAV) - Abstract #2788

ACR 2018 Podcast - Day 2B

Audio Highlights and Interviews from Day 2 at the ACR 2018 meeting - LISTEN HERE

ACR 2018 Podcast - Day 1B

Audio Highlights and Interviews from Day 1 at the ACR 2018 meeting - LISTEN HERE