Psoriasis Increases Risk of Major Adverse Cardiovascular Events Save

A report in the Journal of the American Academy of Dermatology shows that psoriasis duration and inflammation may result in cardiovascular inflammation and an increased risk of major adverse CV events (MACE). (Citation source https://buff.ly/2xB41nf)

A Danish study of 190 psoriasis patients underwent FDG-18 PET scanning. All of these had mild to moderate psoriasis. They found that vascular inflammation was significantly associated with longer disease duration (β = 0.171, P = .002), even after accounting for traditional risk factors for cardiovascular disease such as smoking and a family history of heart attack or stroke.

In a population-based study, they examined 87,000 Danish psoriasis patients and compared their outcomes to 4.2 million people without the condition. They found each year people lived with psoriasis was associated with a 1 percent increase in the future risk of MACE (1.0% per additional year of psoriasis duration [hazard ratio, 1.010; 95% confidence interval, 1.007-1.013]).

While these imaging tests didn’t connect vascular inflammation to an increased risk of heart attacks and strokes, researchers implied a strong connection based on these observational studies.