Monday, 16 Sep 2019

You are here

RheumNow Podcast – Antibiotics Increase RA Risk (8.16.19)

Dr. Jack Cush reports the news and important journal articles from the past week on RheumNow.com.

  1. Nurses' Health Study II shows high gluten intake is not assoc with a greater risk of Psoriasis (HR 1.15;0.98-1.36), Psoriatic arthritis (HR 1.12;0.78-1.62) or Atopic dermatitis (HR 0.91; 0.66-1.25); data frin 85,185 Pso, 85,324 PsA and 63,443 atopic dermatitis patients. https://t.co/P1eWGZZqKl   
  2. Cross sectional analysis of ~3000 and meta-analysis (14 studies) finds #gout has a higher risk of hypothyroidism, esp in female gout pts (OR=2.44;1.15-5.17); Metaanalysis shows an increased risk hypothyroidism in gout (OR=1.51) and hyperuricemic pts (OR=1.34) https://t.co/1w3xfHqryJ 
  3. Lilly announces the results of its phase 4 trial comparing Taltz (IL-17) to Tremfya (IL-23) in mod-severe plaque psoriasis. Taltz had superior skin clearance (PASI 100) at week 12, better PASI 75 at week 2 and PASI 90 at weeks 4 and 8. https://t.co/GzfZoepUrK  
  4. In GCA/Temporal arteritis, when do you start a DMARD/Biologic as a steroid sparing Rx?  
  5. Do we care about opioids?  Nearly 30% of presurgical OA (Spine> Hip & Knee) used prescription opioids. Opioid use was greater with spine OA (vs. knee OA), obesity, smokers, depression, greater pain, higher TJC, and concurrent use of other pain meds https://t.co/ns6JBB7BXU 
  6. Case-control study using the UK Clinical Practice Research database examined 22,677 RA patients 1995–2017) exposed to antibiotics vs. ~90K controls shows the risk of RA is 60% higher if Abx exposed (OR 1.60; 95% CI 1.51–1.68) – is this from microbiome changes? https://t.co/ysfEXnRU3c
  7. RA Disease Activity Drives Lung Complications  
  8. Enbrel Patent Battle Won by Amgen  
  9. "WAR on RA - Part 4: Desperado" is featured on RheumNow. Why the Eagles and Glenn Fry's death should inspire us to better, greater, more and other superlatives in RA. https://t.co/dgShcQpWHP 
  10. Trends in Inflammatory Arthritis Care in Germany  

 

Disclosures: 
The author has received compensation as an advisor or consultant on this subject

Add new comment

More Like This

RheumNow Podcast – The End of Arthritis (9.13.19)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

RheumNow Podcast – Do’s and Don’ts in Spondylitis (9.5.19)

Dr. Jack Cush reviews the news and important research published in the last two weeks on RheumNow.com.

Influenza Vaccination Update

FDA's Vaccines and Related Biological Products Advisory Committee met in Silver Spring, Maryland, on March 6 and 22, 2019, to select the influenza viruses for the composition of the influenza vaccine for the 2019-2020 U.S. influenza season.

RheumNow Podcast - I Wanna New Drug (8-30-19)

Dr. Jack Cush vents on choosing new therapies in rheumatoid arthritis.

RheumNow Podcast – Upadacitinib FDA Approved for RA (8.23.19)

Dr. Jack Cush reports on the news and journal reports from the past week on RheumNow.com, including: how your genetics may shape your microbiome; GERD as a risk factor for TMJ?; how can MDA-5+ dermatomyositis be any worse; new drug happenings; StillsNow.com; and more.