Monday, 18 Mar 2019

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RheumNow Podcast - Death and Surgery (2-22-19)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com:

  1. Swedish Population study shows a 2 fold higher mortality in patients with RA and MSK (SMR 2.2 & 1.5) patients with < 9 years of education compared with those with > 12 years of education. https://t.co/bjil9FAe4I
  2. A prospective clinical registry examined 1,520 deaths among 12,679 RA participants (80,502 PYs). Mortality was strongly associated with Obesity BMI >30 kg/m2; at age 30 HR: 2.00 (1.65,2.42) p<0.001]. https://t.co/T2VIJgdO0F
  3. Review of 541,744 total knee replacement (TKR) in Australia (1999-2017) finds lower revision rates in RA vs. OA, but increased risk of infection in RA (esp. males) https://t.co/rIpSFWSNfY 
  4. Finnish population study of 4180 JIA patients shows JIA mortality not increased (0.6%) vs Nl population. Mean age at death 20.3 yrs; Most common JIA cause was accidents, vs. suicide in controls. JIA pts had less substance abuse and depression https://t.co/9WiJJPxChR     
  5. More than half (53%) of hospital deaths are from sepsis and sepsis is the most common immediate cause of death (35%) according to a medical record review from 6 academic centers https://t.co/Sp5rFTbg3m 
  6. Lupus Microbiome May Drive Disease Activity   http://rheumnow.com/content/lupus-microbiome-may-drive-disease-activity
  7. Safety Warnings for Higher Dose Tofacitinib 
  8. Hip Replacements Lasting 25 Years   
  9. Impressive Survival of Interleukin-1 Inhibitors in Systemic Juvenile Idiopathic Arthritis  

 

Disclosures: 
The author has received compensation as an advisor or consultant on this subject

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