Monday, 24 Feb 2020

You are here

RheumNow Podcast- A Good First Impression (1.24.20)

Dr Jack Cush comments on this week's journal articles, reviews and studies.

  1. Health Care Utilization prior to the Dx of Psoriatic Arthritis #PsA is significantly 2 fold higher. Study of 462 PsA & 2310 comparators shows more visits to PCP for MSK issues in 1-5 yrs prior, as well as use of other MSK specialists in 5 yrs preceding Dx. https://t.co/5729ya9Ahr
  2. Data from the Swedish Rheumatology Quality register (2716 RA pts) shows that biologic naive patients had longer drug survival. Men (HR 0.86) and MTX users (HR 0.85) were less likely to discontinue abatacept, https://t.co/Vhy3XtEg8R
  3. 60% The percentage of patients at @NIH's autoinflammatory disease cohort that are undifferentiated and do not have a specific disease diagnosis -Dr. Amanda Ombrello. #ACR19 @rheumnow https://t.co/d85OtnEA8o
  4. In 80 RA pts, SJC & TJC flares seen in 36% of pts. Pt-reported flares usually reflected incr Dz activity (MD exam & US). Pts & clinicians agreed in 79–93% of joints, moreso SJ than TJ   http://bit.ly/2NS2Fvk
  5. Population based study of ~72K chinese people shows that the DASH diet was assoc with significantly (30%) lower risk of hyperuricemia - more pronounced among older people (≥50 y), women and physically inactive (<0.01 for all). #Gout https://t.co/Ns1KzD5PfM
  6. IL-37 may be a target for psoriasis. IL-37 is downregulated in lesional skin & IL-37 serum levels correlate with psoriasis severity. IL-37 is an anti-inflammatory & immunosuppressive cytokine from IL-1 family. Tofacitinib may increase IL-37 in psoriasis https://t.co/jPaGlcDFV2
  7. Hydroxychloroquine in RA metanalysis shows clinical efficacy of HCQ was similar to or lower than MTX or SSZ monotherapy. When HCQ combined with other DMARDs it increased the clinical efficacy. There is a paucity of data on HCQ structural (Xray) benefits https://t.co/Q5ukHrjybJ
  8. A of TB risk with TNF inhib - Risks by country: - Worldwide - 9.62 cases/1000 pts exposed - Asia, 13.47 /1000 - S America 11.75 /1000 - Europe, 6.28 /1000 patients - North America 4.34 /1000 (low risk (USA, EU) and high risk countries (Asia, S.Amer). https://t.co/MNtnjbEuMS
  9. Anti-transcription intermediary factor 1 (TIF1)-γ autoantibodies are linked with cancer-associated Dermatomyositis in adults https://t.co/DeBoDdEbV1
  10. CDC: 15% of US Adults are Physically Inactive  
  11. Low Risk of Inflammatory Arthritis in Hidradenitis Suppurativa Patients  

 

Disclosures: 
The author has received compensation as an advisor or consultant on this subject

Add new comment

More Like This

RheumNow Podcast- Half-Empty Flu (2.21.20)

Dr Jack Cush reviews the news and journal articles from the past week on RheumNow.com

Primary Care Visits Decline 2008-2016

A national claims-based analysis has shown a consistent decline, by commercially insured adults (18-64 yrs), in primary care physician visits from 2008 to 2016; with nearly one half having no PCP visits in a given year by 2016. 

Efforts to contain costs and improve clinical outcomes often center around coordinated medical care through PCPs.

RheumNow Podcast - RWCS Quick Hits (2.14.20)

Dr. Jack Cush reviews the highlights from the 2020 RWCS meeting in Maui, Hawaii.

RheumNow Podcast- Best Biologics (2.7.20)

Dr Jack Cush reviews the news and journal articles from the past week on RheumNow.com

QD Clinic - "I Don't Know Why I'm Here" Consult

QD Clinic - Lessons from the clinic The Consult that shows up without a cause - and what to do?