Wednesday, 15 Aug 2018

You are here

The RheumNow Week in Review – Life Savers for Rheumatologists (6.29.18)

Dr. Jack Cush reviews selected news and journal reports from the past week on RheumNow.com.

  1. European Commission has approved XELJANZ® (tofacitinib citrate) 5 mg twice daily (BID) in combination with methotrexate (MTX) for the treatment of adults with active psoriatic arthritis (PsA) with an inadequate response to DMARDs https://t.co/G6YYXSuUyQ
  2. Study of 14 EGPA pts shows mean age 12.3 yrs, All w/ Lung, upper airway (85%), skin (71%), GI tract (64%), heart (57%). CNS & renal Dz were rare. Only 31% ANCA+. Compared to adult, kids have more ENT, CV, & GI. https://t.co/v1wwrTUgsT 
  3. MPO (myeloperoxidase) Abs(MPO-ANCA, pANCA) may be associated with a wider variety - GPA, EGPA, microscopic polyangiitis, Goodpastures, PAN, glomerulonephritis, lupus, interstitial lung dz, bronchiectasis, alveolar hemorrhage, RA, IBD, autoimmune liver dz https://t.co/cWb0UeOu0h 
  4. TMP/SMX prophylaxis following rituximab in ANCA+ associated vasculitis reduces infections by 70% (HR 0.30) - 192 AAV pts with 92 infx in 49 pts (only 1 due to PJP). https://t.co/VmVDXQqlSZ 
  5. Taiwan claims analysis of #RA patients shows that despite low rates (10-20%) of influenza vaccination, those vaccinated had a significant ~35% lower rate of death and hospitalization (sepsis, bacteremia, viremia) https://t.co/Y17d66AZnC
  6. HCQ use in Lupus associated with 32% lower risk of all cause mortality at 1 yr. (a Taiwan claims data study of 2287 #SLE patients either on or off plaquenil) https://t.co/qt4nFcYCQw
  7. The risk of psoriatic arthritis in psoriasis is 23.8% according to a systematic review and metanalysis in JAAD (using CASPAR criteria). The incidence of PsA in psoriasis ranged from 0.27-2.7/100PY https://t.co/tnw41vFQe3   
  8. Study of 20,000+ patients receiving knee or hip replacements finds that, compared to OA, #RA patients have a high risk of post-op MI (HZ 3.54) and more revision surgeries (HZ 1.61)over 10 yrs https://t.co/YXH5FqHnr0 
  9. Public Citizen Pressures FDA to Pull Febuxostat   
  10. Ixekizumab Effective in Ankylosing Spondylitis 
Disclosures: 
The author has received compensation as an advisor or consultant on this subject

Add new comment

More Like This

U.S. News 2018-19 Rheumatology Rankings

The Annual U.S. News and World Report Rankings of Hospitals has listed the top contenders in the field of rheumatology. The U.S. News Review rates hospitals nationwide in 16 specialties – including rheumatology. Of the 4,500 hospitals covered by U.S. News that were analyzed, 158 were classified nationally in at least one specialty area.

The RheumNow Week in Review – No Good Gout (8.10.18)

Dr. Jack Cush reviews the news and latest journal articles from the past week on RheumNow.com. Info on Surgery and Hip Fractures, Gout drugs abandoned, Allopurinol escalation, hydroxychloroquine drug levels, how to treat scleroderma in India and exactly who gets back pain.

The RheumNow Week in Review – Handshakes or Hugs (8.3.18)

Dr. Jack Cush reviews the news and highlights from the past week on RheumNow.com, including new treatments for LTBI, gout consequences, RA and offspring risk, PsA risk, and the opioid epidemic effects.

The RheumNow Week in Review – Lupus in the News (7.27.18)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

The RheumNow Week in Review – Cocoon Therapy? (7.20.18)

Dr. Jack Cush reviews highlights from the news and social media on RheumNow.com in the past week.