Monday, 23 Jul 2018

You are here

The RheumNow Week in Review –Fateful Outcomes in Rheumatology (7.13.18)

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.  Fateful outcomes in Rheumatology, what happens to Seronegatives, IL-23 fails, MRI progression, Not all inflammatory back pain becomes SpA:

  1. Canadian population studies shows that hyperlipidemia monitoring (mostly by PCPs) was poor for 5587 RA and 5613 controls; Lipids were measured in 56.6 and 59.5%, respectively https://t.co/gPRf8fIqHf     
  2. Metanalysis shows autoimmune disease significantly co-associated with psychosis (OR 1.26) - positive assoc w/ pernicious anemia (1.91), pemphigoid (1.90), psoriasis (1.70), celiac (1.53) & Graves Dz (1.33); but neg assoc for AS (0.72) & RA (0.65) https://t.co/YiX6tkfEUz
  3. Early Arthritis Clinic in Australia (2008-15) shows significant delays: from symptom onset to rheumatology review = 26.4 wks. Patient delay (8.7 wks) was the longest delay-predicted overall delay. GP  delays associated with lower disease severity & those at a socioeconomic disadvantage https://t.co/giLD90q76K   
  4. 76/156 early RA pts in remission at 1 year were studied (including MRI) at baseline and at 12 months. Despite clinical remission a majority had MRI inflammation (43% synovitis, 39% BM edema, 9% tenosynovitis), and 33% showed MRI progression of bone erosions. https://t.co/VTVxTXXtcU
  5. Claims data study of GPA pts (214 children & 5,352 adults) showed hospitalizations 30% higher in children w/ GPA; who also had 2-3 fold higher rates of leukopenia (RR = 2.6), neutropenia (RR = 2.2) & hypogammaglobulinemia (RR = 3.7) https://t.co/gA1E0yK24n
  6. NIH Rochester Epidemiology Project enrolled adults w/ LBP from 99-03 From 5304 pts with back pain, only 124 patients had new‐onset Inflam LBP (IBP). After 13.2 yrs, only 31% of IBP progressed to SpA; That IBP often resolves may explain difference betw prevalence of IBP (3–6%) & the prev of SpA (0.4–1.3%) https://t.co/e1OeflZuaU   
  7. Testosterone use in USA tripled from 2001 - 2011, mostly men without clear indication. In late 2013 2 studies reported increased MI & CVA risk associated with testosterone use and since decreased 50%. https://t.co/qpKT5WuLru
  8. The Diverse Fate of Seronegative Rheumatoid Arthritis  
  9. Defining Refractory RA by Biologic Use     
  10. IL-23 Inhibitor Fails in Ankylosing Spondylitis    
  11. Hydroxychloroquine Being Over-Dosed with New Guidelines?   
  12. Prescription Drugs and the Effect on Access to Biosimilars in the US   
  13. Upcoming ARTHROS Regional Meetings in Chicago, Nashville, Boston and Washington, DC  

 

Disclosures: 
The author has received compensation as an advisor or consultant on this subject

Add new comment

More Like This

The RheumNow Week in Review – Cocoon Therapy? (7.20.18)

Dr. Jack Cush reviews highlights from the news and social media on RheumNow.com in the past week. 

Proposed Changes for 2019 Medicare Fee Schedule

On July 12th the Centers for Medicare & Medicaid Services (CMS) released its proposed rule changes for the 2019 Medicare physician fee schedule.  This year, CMS has combined the Medicare physician fee schedule proposed rule with recommendations for the Quality Payment Program (QPP), which will be officially published in the Federal Register on July 27.

Trend Towards Fewer Self-Employed Physicians

 

A nationwide survey study analyzed healthcare provider (HCP) employment type (self-employed, employed by private sector, or employed by government) and annual labor earnings (2001 to 2015) and found that the health care landscape is changing with few self-employed practitioners and more being larger organizations. 

The RheumNow Week in Review – Life Savers for Rheumatologists (6.29.18)

Dr. Jack Cush reviews selected news and journal reports from the past week on RheumNow.com.

The RheumNow Week in Review – EULAR18 Epilogue (6.22.18)

Dr. Jack Cush reviews EULAR 2018 and the past week's news and reports from RheumNow.com, including DMARDs in OA, the price of Penicillamine, Infections when ANCA+, CV outcomes in gout, NSAIDs in Pregnancy and Seropostive vs. Seronegative Outcomes.