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The RWCS - RheumNow Week in Review - 9 February 2018

Dr. Jack Cush reviews highlights, news and recent research published this week on RheumNow.com. This week's report includes news and education from the RWCS meeting in Maui. Also featured are uricase treatments for gout, exercise in RA, CVD in lupus, NFC predicting mortality in systemic sclerosis, Uveitis predicting AS and future manpower shortages in rheumatology.

  1. RWCS 2018 meeting – daily podcasts available here:  https://buff.ly/2BPCMrQ  https://buff.ly/2BPCLEi
  2. Phase 2 trial of SEL-212 (pegsiticase with attached rapamycin nanoparticle) sh ows efficacy and tolerability in tophaceous gout (22% flare rate, 2 infusion reactions). #RWCS https://t.co/AXx5HFjCJb
  3. Pegloticase tolerizing regimen in the Triple study shows improved efficacy with initial 3 weekly infusions inducing high zone tolerance https://t.co/js3aFP6Wy5
  4. DANBIO Study in Denmark shows no increase in healthcare utilization/resources when forced to switch to biosimilar. #RWCS @RheumNow https://t.co/Z0QWmW2uik
  5. Dr Bevra Hahn on factors predisposing SLE Pts to C V events- pred>20mg, high dz activity, high CRP plus usual (HTN, DM, male, age, etc) #rwcs https://t.co/HwY3wBG4WZ
  6. 150 mins of moderate or 75 mins of vigorous exercise weekly may improve HAQ and outcomes in RA. #RWCS @RheumNow https://t.co/A8xy9CJ2uq
  7. What is OCD? a rheumatologist would say OsteoChondritis Dessicans - a condition of adolescents & young adults w/ pain, stiffness, catching or effusion, usually the knee. Caused by focal, alterations in subchondral bone causing instability and risk of OA. https://t.co/7GWlNhf44e
  8. 142 pts with active GN due to ANCA-assoc. vasculitis achieved remission in 2 RCTs; post hoc analysis showed 42% had persistent proteinuria & hematuria. But only persistent hematuria was associated with a significantly higher (4 fold) risk of future relapse https://t.co/AxezacEHYe
  9. Recurrent Uveitis Increases the Risk of Ankylosing Spondylitis  
  10. Nailfold Capillaroscopy Portends Mortality risk in Systemic Sclerosis   
  11. Future Shortage of Rheumatologists in the USA   

 

Disclosures: 
The author has received compensation as an advisor or consultant on this subject

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