Wednesday, 17 Oct 2018

You are here

Weight Loss Lessens Knee Pain in Obese

Obese knee osteoarthritis (OA) patients who lose > 20% of their weight were in significantly less pain, had better function and improved quality of life. 

A study in Arthritis Care & Research reports the results of a secondary analysis from the Intensive Diet and Exercise for Arthritis (IDEA) study that included 240 overweight and obese adults with pain and radiographic knee OA. Patients were randomized to one of 4 groups and followed for an 18‐month period. (Citation source: bit.ly/2ymt6UI)

A significant dose responses to weight loss was achieved for pain reduction (p = 0.01), function (p = 0.0006), 6‐minute walk distance (p < 0.0001), quality of life (HRQL), knee joint compressive force (p < 0.0001), and IL‐6 (p = 0.002).

Greater weight loss resulted in superior clinical and mechanstic outcomes with the highest weight loss group (≥20% group) distinguishing itself on all measures compared to the <5% and ≥5% groups; the ≥20% group had 25% less pain and better function than the ≥ 10% group, and significantly (p = 0.006) better physical HRQL.

Overall 10% or more weight loss resulted in a 50% reduction in pain, and patients also reported significant improvements in mobility and daily function. 

It is unclear what the long-term effects of weight loss on knee joint pain or mobility will be from this study. 

Weight loss not only improved knee pain, but also was shown to decrease inflammation with lower IL-6 levels.

 

 

 

Disclosures: 
The author has no conflicts of interest to disclose related to this subject

Add new comment

More Like This

Complex Pain Syndromes in the Emergency Room

Emergency physician Chris Hahn, MD, doesn't have any trouble conjuring a simple definition of fibromyalgia. "Just think about the most annoying chief complaints you can imagine. That's the diagnostic criteria."

Carpal Tunnel Syndrome - a Leading Cause of Work Related Disability

MMWR reports that workers’ compensation claims for carpal tunnel syndrome (CTS) in California during 2007–2014 were 6.3 per 10,000 full-time equivalent workers, with female workers and workers in industries that manufacture apparel, process food, and perform administrative work being at highest risk for CTS.

Anxiety and Depression are Common in Arthritis Patients

The high prevalence of symptoms of anxiety and depression among adults with arthritis warrants awareness, screening, and subsequent treatment of these conditions. Health care providers can refer patients to mental health professionals and self-management education programs, and encourage physical activity to reduce anxiety and depression symptoms and improve quality of life.

FDA's Opioid Analgesic Risk Evaluation and Mitigation Strategy (REMS) Finalized

In response to the growing opioid crisis, the US Food and Drug Administration has approved the final Opioid Analgesic Risk Evaluation and Mitigation Strategy (REMS), designed to reduce the risk of abuse, misuse, addiction, overdose, and deaths due to prescription opioid analgesics.

Lower Income Elderly are More Likely to Use Opioids

The Journal of Gerontology reports that the poorest of the elderly are the most likely to receive prescription opioids.