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Rheumatoid Arthritis

      Beyond the Scale: Do GLP-1RAs Offer More Than Weight Loss in PsA?

      Over 70% of patients with psoriatic arthritis (PsA) s

      Dr. John Cush RheumNow

      2 months ago
      Beyond the Scale: Do GLP-1RAs Offer More Than Weight Loss in PsA? Over 70% of patients with psoriatic arthritis (PsA) struggle with excess weight, amplifying synovio-entheseal inflammation and blunting biologic response. https://t.co/pAIXkdazci https://t.co/vQTn3BWv2r
      CT imaging in RA
      Body composition changes beyond BMI

      489 RA vs 397 ctrl

      RA asso w/
      -increased subcutaneous fat
      -incre

      Aurelie Najm AurelieRheumo

      2 months ago
      CT imaging in RA Body composition changes beyond BMI 489 RA vs 397 ctrl RA asso w/ -increased subcutaneous fat -increased intermuscular adipose tissue -poorer muscle quality Looks like it represent “hidden obesity” with more by fat redistribution and myosteatosis #OP0348
      And now does MRI do better than US at predicting RA progression in at risk pts?

      Short answer: No likely too sensitive!

      Aurelie Najm AurelieRheumo

      2 months ago
      And now does MRI do better than US at predicting RA progression in at risk pts? Short answer: No likely too sensitive! 130 anti-CCP+ symptomatic pts 36.9% progressed BL US positivity predicted progression HR 2.8 MRI showed prevalence of subclinical disease synovitis >80%
      Detecting subclinica tenosynovitis in pts at risk for RA: who does it better US or DixonMRI?

      65 pts RA CSA, US detected

      Aurelie Najm AurelieRheumo

      2 months ago
      Detecting subclinica tenosynovitis in pts at risk for RA: who does it better US or DixonMRI? 65 pts RA CSA, US detected only ~23% of cases identified by Dixon US misses most! But are they “real” tenosynovitis? MRI (5-min, no contrast) higher sens US higher spe Shall we do https://t.co/stsMRdj9eY
      #EULAR2026 POS0172 #Lupus arthritis is the most common domain in RCTs but SLEDAI-MSK or BILAG-MSK isn’t satisfactory.

      Md Yuzaiful Md Yusof Yuz6Yusof

      2 months ago
      #EULAR2026 POS0172 #Lupus arthritis is the most common domain in RCTs but SLEDAI-MSK or BILAG-MSK isn’t satisfactory. Look out for the role out of LAMDA once externally validated using independent trial datasets. 4 candidates: SJC28, ESR, VAS Phy MSK, & VAS Pa Pain @RheumNow https://t.co/QJ51ETLSSN
      Lung US for RA-ILD screening
      Comparison with diagnostic scores

      147 RA pts (68 ILD on HRCT)
      Asymptomatic cohort
      Sens 9

      Aurelie Najm AurelieRheumo

      2 months ago
      Lung US for RA-ILD screening Comparison with diagnostic scores 147 RA pts (68 ILD on HRCT) Asymptomatic cohort Sens 95.4% Spe 77.7% Risk scores alone performed poorly. Combining US + risk scores boosted sensitivity to 100% → promising low-cost screening tool alongside HRCT. https://t.co/7C4zClaxry
      Can AI read 20 years of RA X-rays?

      And how much faster/better than us?

      20 years ESPOIR cohort 7500+ joints
      RADAR alg

      Aurelie Najm AurelieRheumo

      2 months ago
      Can AI read 20 years of RA X-rays? And how much faster/better than us? 20 years ESPOIR cohort 7500+ joints RADAR algorithm 94–95% accuracy compared with expert readers 99% spe 93% sens #OP0344 #EULAR2026 @RheumNow https://t.co/8hFHCY4SaY
      Can AI spot RA inflammation from a thermal hand scan?

      Cohort 100 RA pts

      AI model analysing thermal images detected US

      Aurelie Najm AurelieRheumo

      2 months ago
      Can AI spot RA inflammation from a thermal hand scan? Cohort 100 RA pts AI model analysing thermal images detected US PD+ wrist inflammation AUC 0.87 Main features wrist temperature & heat-pattern With all due validation could this be the next mass screening tool for RA? https://t.co/2AzXj5yQJI
      A biomarker for CV disease in RA?

      Anti-CXCR3 antibodies asso w/ atherosclerosis

      Confirmed in a validation cohort

      Ad

      Aurelie Najm AurelieRheumo

      2 months ago
      A biomarker for CV disease in RA? Anti-CXCR3 antibodies asso w/ atherosclerosis Confirmed in a validation cohort Adding Ab profile to the mSCORE increases AUC from 0.6 to 0.9 Sens from 30 to 69% How does it compare with other ways of detecting atherosclerosis? #POS0899 https://t.co/O7bsLrVyzo
      How to treat #RA-#ILD

      Similar to #IPF
      Occurs older men esp
      Smoking risk
      Vaccines
      Etc

      Philippe Dieude
      #HOT #EULAR2026

      Janet Pope Janetbirdope

      2 months ago
      How to treat #RA-#ILD Similar to #IPF Occurs older men esp Smoking risk Vaccines Etc Philippe Dieude #HOT #EULAR2026 @RheumNow https://t.co/F4h9daSLhF
      Which b/tsDMARDs are effective in #axSpA? Stratified by extramusculoskeletal manifestations

      Check out the latest update

      Nelly ZIADE 🍀 Nellziade

      2 months ago
      Which b/tsDMARDs are effective in #axSpA? Stratified by extramusculoskeletal manifestations Check out the latest update of the treatment heatmap 🔥 By Astrid van Tubergen At axial and peripheral SpA at a crossroads session #EULAR2026 @RheumNow https://t.co/uTxEJqbDBm
      Controversial

      #Rheumatoid #arthritis disease activity
      May not affect #ILD
      BUT affects #mortality
      level evidence +/-

      Janet Pope Janetbirdope

      2 months ago
      Controversial #Rheumatoid #arthritis disease activity May not affect #ILD BUT affects #mortality level evidence +/- PHillippe Dieude said #Rx from RCTs #IS Ex #rituximab #antifibrotics #nintedanib #nerandomilast HOw to Treat RA-ILD June 5 #EULAR2026 @RheumNow @eular_ARD https://t.co/R60nX6XzL8
      What b/ts DMARDs are effective and not effective in axSpA?
      Prof. Astrid van Tubergen presents this very informative sum

      sheila RHEUMarampa

      2 months ago
      What b/ts DMARDs are effective and not effective in axSpA? Prof. Astrid van Tubergen presents this very informative summary slide summarizing treatment in axSpA. @RheumNow #EULAR2026 https://t.co/5udGPB1Hrr
      Not all #RA pts respond equally to advanced therapy. 10-variable risk model >18k US pts: low baseline disease activit

      Jiha Lee JihaRheum

      2 months ago
      Not all #RA pts respond equally to advanced therapy. 10-variable risk model >18k US pts: low baseline disease activity, fewer comorbidities, and no prior biologics 5x more likely to achieve remission at 1yr (34% vs 7%). RWD for precision care @RheumNow #EULAR2026 POS0257
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