Rheumatoid Arthritis
Dr. John Cush RheumNow
2 months ago
Beyond the Scale: Do GLP-1RAs Offer More Than Weight Loss in PsA?
Over 70% of patients with psoriatic arthritis (PsA) struggle with excess weight, amplifying synovio-entheseal inflammation and blunting biologic response.
https://t.co/pAIXkdazci https://t.co/vQTn3BWv2r
Aurelie Najm AurelieRheumo
2 months ago
CT imaging in RA
Body composition changes beyond BMI
489 RA vs 397 ctrl
RA asso w/
-increased subcutaneous fat
-increased intermuscular adipose tissue -poorer muscle quality
Looks like it represent “hidden obesity” with more by fat redistribution and myosteatosis
#OP0348
Aurelie Najm AurelieRheumo
2 months ago
And now does MRI do better than US at predicting RA progression in at risk pts?
Short answer: No likely too sensitive!
130 anti-CCP+ symptomatic pts
36.9% progressed
BL US positivity predicted progression HR 2.8
MRI showed prevalence of subclinical disease synovitis >80%
Aurelie Najm AurelieRheumo
2 months ago
Detecting subclinica tenosynovitis in pts at risk for RA: who does it better US or DixonMRI?
65 pts RA CSA, US detected only ~23% of cases identified by Dixon
US misses most! But are they “real” tenosynovitis?
MRI (5-min, no contrast) higher sens
US higher spe
Shall we do https://t.co/stsMRdj9eY
Md Yuzaiful Md Yusof Yuz6Yusof
2 months ago
#EULAR2026 POS0172 #Lupus arthritis is the most common domain in RCTs but SLEDAI-MSK or BILAG-MSK isn’t satisfactory. Look out for the role out of LAMDA once externally validated using independent trial datasets. 4 candidates: SJC28, ESR, VAS Phy MSK, & VAS Pa Pain @RheumNow https://t.co/QJ51ETLSSN
Aurelie Najm AurelieRheumo
2 months ago
Lung US for RA-ILD screening
Comparison with diagnostic scores
147 RA pts (68 ILD on HRCT)
Asymptomatic cohort
Sens 95.4% Spe 77.7%
Risk scores alone performed poorly.
Combining US + risk scores boosted sensitivity to 100% → promising low-cost screening tool alongside HRCT. https://t.co/7C4zClaxry
Aurelie Najm AurelieRheumo
2 months ago
Can AI read 20 years of RA X-rays?
And how much faster/better than us?
20 years ESPOIR cohort 7500+ joints
RADAR algorithm
94–95% accuracy compared with expert readers
99% spe 93% sens
#OP0344 #EULAR2026 @RheumNow https://t.co/8hFHCY4SaY
Aurelie Najm AurelieRheumo
2 months ago
Can AI spot RA inflammation from a thermal hand scan?
Cohort 100 RA pts
AI model analysing thermal images detected US PD+ wrist inflammation AUC 0.87
Main features wrist temperature & heat-pattern
With all due validation could this be the next mass screening tool for RA? https://t.co/2AzXj5yQJI
Aurelie Najm AurelieRheumo
2 months ago
A biomarker for CV disease in RA?
Anti-CXCR3 antibodies asso w/ atherosclerosis
Confirmed in a validation cohort
Adding Ab profile to the mSCORE increases
AUC from 0.6 to 0.9
Sens from 30 to 69%
How does it compare with other ways of detecting atherosclerosis?
#POS0899 https://t.co/O7bsLrVyzo
Janet Pope Janetbirdope
2 months ago
How to treat #RA-#ILD
Similar to #IPF
Occurs older men esp
Smoking risk
Vaccines
Etc
Philippe Dieude
#HOT #EULAR2026 @RheumNow https://t.co/F4h9daSLhF
Nelly ZIADE 🍀 Nellziade
2 months ago
Which b/tsDMARDs are effective in #axSpA? Stratified by extramusculoskeletal manifestations
Check out the latest update of the treatment heatmap 🔥
By Astrid van Tubergen
At axial and peripheral SpA at a crossroads session
#EULAR2026
@RheumNow https://t.co/uTxEJqbDBm
Janet Pope Janetbirdope
2 months ago
Controversial
#Rheumatoid #arthritis disease activity
May not affect #ILD
BUT affects #mortality
level evidence +/-
PHillippe Dieude said
#Rx from RCTs
#IS
Ex #rituximab
#antifibrotics
#nintedanib
#nerandomilast
HOw to Treat RA-ILD June 5
#EULAR2026 @RheumNow @eular_ARD https://t.co/R60nX6XzL8
sheila RHEUMarampa
2 months ago
What b/ts DMARDs are effective and not effective in axSpA?
Prof. Astrid van Tubergen presents this very informative summary slide summarizing treatment in axSpA.
@RheumNow #EULAR2026 https://t.co/5udGPB1Hrr
Jiha Lee JihaRheum
2 months ago
Not all #RA pts respond equally to advanced therapy. 10-variable risk model >18k US pts: low baseline disease activity, fewer comorbidities, and no prior biologics 5x more likely to achieve remission at 1yr (34% vs 7%). RWD for precision care @RheumNow #EULAR2026 POS0257